| Full name: solute carrier family 16 member 4 | Alias Symbol: MCT4|MCT5 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 9122 | HGNC ID: HGNC:10925 | Ensembl Gene: ENSG00000168679 | OMIM ID: 603878 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC16A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC16A4 | 9122 | 205234_at | -1.1146 | 0.0387 | |
| GSE20347 | SLC16A4 | 9122 | 205234_at | 0.0332 | 0.8347 | |
| GSE23400 | SLC16A4 | 9122 | 205234_at | -0.0170 | 0.5781 | |
| GSE26886 | SLC16A4 | 9122 | 205234_at | 0.5443 | 0.0035 | |
| GSE29001 | SLC16A4 | 9122 | 205234_at | 0.1382 | 0.4428 | |
| GSE38129 | SLC16A4 | 9122 | 205234_at | -0.3548 | 0.1827 | |
| GSE45670 | SLC16A4 | 9122 | 205234_at | -2.1343 | 0.0000 | |
| GSE53622 | SLC16A4 | 9122 | 22950 | -0.8143 | 0.0000 | |
| GSE53624 | SLC16A4 | 9122 | 22950 | -0.7833 | 0.0000 | |
| GSE63941 | SLC16A4 | 9122 | 205234_at | -5.7567 | 0.0002 | |
| GSE77861 | SLC16A4 | 9122 | 205234_at | 0.0686 | 0.5039 | |
| GSE97050 | SLC16A4 | 9122 | A_33_P3227920 | -0.0308 | 0.9163 | |
| SRP007169 | SLC16A4 | 9122 | RNAseq | 2.1972 | 0.0036 | |
| SRP064894 | SLC16A4 | 9122 | RNAseq | -0.0972 | 0.7447 | |
| SRP133303 | SLC16A4 | 9122 | RNAseq | -0.1085 | 0.5075 | |
| SRP159526 | SLC16A4 | 9122 | RNAseq | -0.3611 | 0.3995 | |
| SRP193095 | SLC16A4 | 9122 | RNAseq | 0.2835 | 0.1246 | |
| SRP219564 | SLC16A4 | 9122 | RNAseq | 0.6202 | 0.3367 | |
| TCGA | SLC16A4 | 9122 | RNAseq | -0.6162 | 0.0026 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by SLC16A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC16A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC16A4 | 9122 | 0 | 11 | 19 | |
| GSE20123 | SLC16A4 | 9122 | 0 | 11 | 19 | |
| GSE43470 | SLC16A4 | 9122 | 0 | 8 | 35 | |
| GSE46452 | SLC16A4 | 9122 | 2 | 1 | 56 | |
| GSE47630 | SLC16A4 | 9122 | 9 | 5 | 26 | |
| GSE54993 | SLC16A4 | 9122 | 0 | 1 | 69 | |
| GSE54994 | SLC16A4 | 9122 | 7 | 4 | 42 | |
| GSE60625 | SLC16A4 | 9122 | 0 | 0 | 11 | |
| GSE74703 | SLC16A4 | 9122 | 0 | 7 | 29 | |
| GSE74704 | SLC16A4 | 9122 | 0 | 7 | 13 | |
| TCGA | SLC16A4 | 9122 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 81; Total Number of normals: 380.
Somatic mutations of SLC16A4:
Generating mutation plots.
Highly correlated genes for SLC16A4:
Showing top 20/1357 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC16A4 | GPIHBP1 | 0.8557 | 3 | 0 | 3 |
| SLC16A4 | HGF | 0.841137 | 4 | 0 | 4 |
| SLC16A4 | LRRN4CL | 0.819132 | 7 | 0 | 7 |
| SLC16A4 | TNFSF12 | 0.808263 | 3 | 0 | 3 |
| SLC16A4 | PEG3 | 0.800914 | 6 | 0 | 6 |
| SLC16A4 | GIMAP5 | 0.799225 | 3 | 0 | 3 |
| SLC16A4 | RCN2 | 0.798663 | 3 | 0 | 3 |
| SLC16A4 | CYYR1 | 0.793769 | 5 | 0 | 5 |
| SLC16A4 | FGF7 | 0.791675 | 9 | 0 | 9 |
| SLC16A4 | GNG2 | 0.789218 | 5 | 0 | 5 |
| SLC16A4 | SGCD | 0.783906 | 7 | 0 | 7 |
| SLC16A4 | SMIM10 | 0.783434 | 5 | 0 | 5 |
| SLC16A4 | MEOX2 | 0.781873 | 8 | 0 | 7 |
| SLC16A4 | CNRIP1 | 0.780611 | 7 | 0 | 6 |
| SLC16A4 | ABCA8 | 0.779497 | 8 | 0 | 8 |
| SLC16A4 | OGN | 0.779193 | 8 | 0 | 8 |
| SLC16A4 | EBF1 | 0.776799 | 7 | 0 | 7 |
| SLC16A4 | CD34 | 0.774761 | 6 | 0 | 6 |
| SLC16A4 | MGARP | 0.769096 | 3 | 0 | 3 |
| SLC16A4 | SLC39A13 | 0.766953 | 3 | 0 | 3 |
For details and further investigation, click here
