| Full name: ribosomal RNA processing 1B | Alias Symbol: Nnp1|RRP1|PPP1R136 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 23076 | HGNC ID: HGNC:23818 | Ensembl Gene: ENSG00000160208 | OMIM ID: 610654 |
| Drug and gene relationship at DGIdb | |||
Expression of RRP1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RRP1B | 23076 | 212846_at | 0.9544 | 0.0725 | |
| GSE20347 | RRP1B | 23076 | 212846_at | 0.4505 | 0.0008 | |
| GSE23400 | RRP1B | 23076 | 212846_at | 0.6133 | 0.0000 | |
| GSE26886 | RRP1B | 23076 | 212846_at | 0.1388 | 0.6181 | |
| GSE29001 | RRP1B | 23076 | 212846_at | 0.4135 | 0.1609 | |
| GSE38129 | RRP1B | 23076 | 212846_at | 0.4470 | 0.0005 | |
| GSE45670 | RRP1B | 23076 | 212846_at | 0.4856 | 0.0043 | |
| GSE53622 | RRP1B | 23076 | 41755 | 0.3461 | 0.0000 | |
| GSE53624 | RRP1B | 23076 | 41755 | 0.3999 | 0.0000 | |
| GSE63941 | RRP1B | 23076 | 212846_at | -0.2019 | 0.6440 | |
| GSE77861 | RRP1B | 23076 | 212846_at | 0.2389 | 0.2886 | |
| GSE97050 | RRP1B | 23076 | A_24_P944040 | 0.5186 | 0.1505 | |
| SRP007169 | RRP1B | 23076 | RNAseq | 0.5690 | 0.1788 | |
| SRP008496 | RRP1B | 23076 | RNAseq | 0.3347 | 0.3211 | |
| SRP064894 | RRP1B | 23076 | RNAseq | 0.3092 | 0.1169 | |
| SRP133303 | RRP1B | 23076 | RNAseq | 0.1526 | 0.2025 | |
| SRP159526 | RRP1B | 23076 | RNAseq | 0.4306 | 0.0030 | |
| SRP193095 | RRP1B | 23076 | RNAseq | 0.4213 | 0.0000 | |
| SRP219564 | RRP1B | 23076 | RNAseq | 0.9620 | 0.0921 | |
| TCGA | RRP1B | 23076 | RNAseq | 0.0636 | 0.2044 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RRP1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RRP1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RRP1B | 23076 | 2 | 8 | 20 | |
| GSE20123 | RRP1B | 23076 | 2 | 8 | 20 | |
| GSE43470 | RRP1B | 23076 | 0 | 13 | 30 | |
| GSE46452 | RRP1B | 23076 | 1 | 21 | 37 | |
| GSE47630 | RRP1B | 23076 | 6 | 17 | 17 | |
| GSE54993 | RRP1B | 23076 | 8 | 1 | 61 | |
| GSE54994 | RRP1B | 23076 | 4 | 8 | 41 | |
| GSE60625 | RRP1B | 23076 | 0 | 0 | 11 | |
| GSE74703 | RRP1B | 23076 | 0 | 10 | 26 | |
| GSE74704 | RRP1B | 23076 | 1 | 4 | 15 | |
| TCGA | RRP1B | 23076 | 7 | 40 | 49 |
Total number of gains: 31; Total number of losses: 130; Total Number of normals: 327.
Somatic mutations of RRP1B:
Generating mutation plots.
Highly correlated genes for RRP1B:
Showing top 20/1366 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RRP1B | STAG1 | 0.815626 | 3 | 0 | 3 |
| RRP1B | PIGM | 0.783712 | 3 | 0 | 3 |
| RRP1B | SGSH | 0.783356 | 3 | 0 | 3 |
| RRP1B | FAM53B | 0.78096 | 3 | 0 | 3 |
| RRP1B | PUS10 | 0.772045 | 3 | 0 | 3 |
| RRP1B | SAP130 | 0.747086 | 3 | 0 | 3 |
| RRP1B | MRPL11 | 0.741012 | 3 | 0 | 3 |
| RRP1B | CWF19L1 | 0.729311 | 4 | 0 | 4 |
| RRP1B | SLC39A3 | 0.726801 | 3 | 0 | 3 |
| RRP1B | PET117 | 0.723986 | 3 | 0 | 3 |
| RRP1B | NCOA6 | 0.721088 | 4 | 0 | 3 |
| RRP1B | RHBDD2 | 0.720546 | 4 | 0 | 3 |
| RRP1B | NTPCR | 0.719759 | 3 | 0 | 3 |
| RRP1B | B3GALT6 | 0.716302 | 4 | 0 | 3 |
| RRP1B | ZBTB9 | 0.713114 | 6 | 0 | 5 |
| RRP1B | NOM1 | 0.712953 | 4 | 0 | 4 |
| RRP1B | ARHGAP18 | 0.712916 | 3 | 0 | 3 |
| RRP1B | OSGEPL1 | 0.711522 | 4 | 0 | 4 |
| RRP1B | CDK2AP1 | 0.709424 | 4 | 0 | 4 |
| RRP1B | PA2G4 | 0.707997 | 4 | 0 | 4 |
For details and further investigation, click here
