| Full name: dipeptidyl peptidase 7 | Alias Symbol: DPPII|DPP2 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 29952 | HGNC ID: HGNC:14892 | Ensembl Gene: ENSG00000176978 | OMIM ID: 610537 |
| Drug and gene relationship at DGIdb | |||
Expression of DPP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPP7 | 29952 | 224814_at | -0.0427 | 0.9637 | |
| GSE26886 | DPP7 | 29952 | 224814_at | 0.6830 | 0.0006 | |
| GSE45670 | DPP7 | 29952 | 224814_at | 0.1050 | 0.3231 | |
| GSE53622 | DPP7 | 29952 | 92854 | 0.1678 | 0.0228 | |
| GSE53624 | DPP7 | 29952 | 92854 | 0.3528 | 0.0000 | |
| GSE63941 | DPP7 | 29952 | 224814_at | -0.6253 | 0.1069 | |
| GSE77861 | DPP7 | 29952 | 224814_at | 0.1835 | 0.5617 | |
| GSE97050 | DPP7 | 29952 | A_33_P3387956 | 0.3029 | 0.1943 | |
| SRP007169 | DPP7 | 29952 | RNAseq | -0.5629 | 0.1212 | |
| SRP008496 | DPP7 | 29952 | RNAseq | -0.4170 | 0.0441 | |
| SRP064894 | DPP7 | 29952 | RNAseq | 0.6962 | 0.0827 | |
| SRP133303 | DPP7 | 29952 | RNAseq | -0.2119 | 0.1968 | |
| SRP159526 | DPP7 | 29952 | RNAseq | 0.4332 | 0.0500 | |
| SRP193095 | DPP7 | 29952 | RNAseq | 0.1516 | 0.2595 | |
| SRP219564 | DPP7 | 29952 | RNAseq | 0.5243 | 0.1935 | |
| TCGA | DPP7 | 29952 | RNAseq | -0.1114 | 0.0860 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DPP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPP7 | 29952 | 5 | 7 | 18 | |
| GSE20123 | DPP7 | 29952 | 5 | 7 | 18 | |
| GSE43470 | DPP7 | 29952 | 3 | 7 | 33 | |
| GSE46452 | DPP7 | 29952 | 6 | 13 | 40 | |
| GSE47630 | DPP7 | 29952 | 6 | 15 | 19 | |
| GSE54993 | DPP7 | 29952 | 3 | 3 | 64 | |
| GSE54994 | DPP7 | 29952 | 12 | 8 | 33 | |
| GSE60625 | DPP7 | 29952 | 0 | 0 | 11 | |
| GSE74703 | DPP7 | 29952 | 3 | 5 | 28 | |
| GSE74704 | DPP7 | 29952 | 3 | 5 | 12 | |
| TCGA | DPP7 | 29952 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of DPP7:
Generating mutation plots.
Highly correlated genes for DPP7:
Showing top 20/329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPP7 | MRPL41 | 0.771423 | 3 | 0 | 3 |
| DPP7 | GAS6 | 0.760611 | 3 | 0 | 3 |
| DPP7 | CLSTN1 | 0.756339 | 3 | 0 | 3 |
| DPP7 | NPHP4 | 0.749357 | 3 | 0 | 3 |
| DPP7 | ZBED1 | 0.735973 | 4 | 0 | 4 |
| DPP7 | PPP1R35 | 0.732272 | 3 | 0 | 3 |
| DPP7 | RNF213 | 0.727827 | 3 | 0 | 3 |
| DPP7 | FAM193B | 0.723024 | 3 | 0 | 3 |
| DPP7 | FIP1L1 | 0.7211 | 3 | 0 | 3 |
| DPP7 | NAP1L1 | 0.711323 | 3 | 0 | 3 |
| DPP7 | RARRES1 | 0.710075 | 3 | 0 | 3 |
| DPP7 | CHCHD6 | 0.706091 | 3 | 0 | 3 |
| DPP7 | CLK2 | 0.70393 | 3 | 0 | 3 |
| DPP7 | PLOD1 | 0.700485 | 4 | 0 | 3 |
| DPP7 | SLC25A32 | 0.698946 | 3 | 0 | 3 |
| DPP7 | POLR2J | 0.698906 | 4 | 0 | 3 |
| DPP7 | C3orf33 | 0.696062 | 3 | 0 | 3 |
| DPP7 | IFT140 | 0.692216 | 3 | 0 | 3 |
| DPP7 | FBXW5 | 0.691327 | 3 | 0 | 3 |
| DPP7 | SLC39A3 | 0.690516 | 4 | 0 | 4 |
For details and further investigation, click here
