| Full name: intraflagellar transport 88 | Alias Symbol: hTg737|Tg737|D13S1056E|MGC26259 | ||
| Type: protein-coding gene | Cytoband: 13q12.11 | ||
| Entrez ID: 8100 | HGNC ID: HGNC:20606 | Ensembl Gene: ENSG00000032742 | OMIM ID: 600595 |
| Drug and gene relationship at DGIdb | |||
Expression of IFT88:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFT88 | 8100 | 204703_at | -0.2684 | 0.4575 | |
| GSE20347 | IFT88 | 8100 | 204703_at | -0.0665 | 0.6187 | |
| GSE23400 | IFT88 | 8100 | 204703_at | -0.1551 | 0.0019 | |
| GSE26886 | IFT88 | 8100 | 204703_at | 0.3998 | 0.1711 | |
| GSE29001 | IFT88 | 8100 | 204703_at | -0.1197 | 0.6257 | |
| GSE38129 | IFT88 | 8100 | 204703_at | -0.1260 | 0.3670 | |
| GSE45670 | IFT88 | 8100 | 204703_at | -0.3105 | 0.0904 | |
| GSE53622 | IFT88 | 8100 | 54813 | 0.1312 | 0.1730 | |
| GSE53624 | IFT88 | 8100 | 54813 | 0.0607 | 0.4281 | |
| GSE63941 | IFT88 | 8100 | 204703_at | -0.9487 | 0.0313 | |
| GSE77861 | IFT88 | 8100 | 204703_at | -0.0763 | 0.6521 | |
| GSE97050 | IFT88 | 8100 | A_23_P48339 | -0.3311 | 0.2662 | |
| SRP007169 | IFT88 | 8100 | RNAseq | 0.5879 | 0.2609 | |
| SRP064894 | IFT88 | 8100 | RNAseq | 0.1928 | 0.2055 | |
| SRP133303 | IFT88 | 8100 | RNAseq | -0.1701 | 0.3000 | |
| SRP159526 | IFT88 | 8100 | RNAseq | 0.1063 | 0.6614 | |
| SRP193095 | IFT88 | 8100 | RNAseq | 0.0143 | 0.9282 | |
| SRP219564 | IFT88 | 8100 | RNAseq | -0.3951 | 0.3177 | |
| TCGA | IFT88 | 8100 | RNAseq | -0.0465 | 0.5562 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFT88 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFT88:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFT88 | 8100 | 1 | 15 | 14 | |
| GSE20123 | IFT88 | 8100 | 1 | 14 | 15 | |
| GSE43470 | IFT88 | 8100 | 2 | 13 | 28 | |
| GSE46452 | IFT88 | 8100 | 0 | 33 | 26 | |
| GSE47630 | IFT88 | 8100 | 3 | 26 | 11 | |
| GSE54993 | IFT88 | 8100 | 11 | 2 | 57 | |
| GSE54994 | IFT88 | 8100 | 1 | 13 | 39 | |
| GSE60625 | IFT88 | 8100 | 0 | 3 | 8 | |
| GSE74703 | IFT88 | 8100 | 2 | 10 | 24 | |
| GSE74704 | IFT88 | 8100 | 0 | 12 | 8 | |
| TCGA | IFT88 | 8100 | 6 | 43 | 47 |
Total number of gains: 27; Total number of losses: 184; Total Number of normals: 277.
Somatic mutations of IFT88:
Generating mutation plots.
Highly correlated genes for IFT88:
Showing top 20/475 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFT88 | PDK2 | 0.78205 | 3 | 0 | 3 |
| IFT88 | ZXDA | 0.753859 | 3 | 0 | 3 |
| IFT88 | ECD | 0.72952 | 3 | 0 | 3 |
| IFT88 | TSHZ1 | 0.721046 | 3 | 0 | 3 |
| IFT88 | SORCS1 | 0.716857 | 3 | 0 | 3 |
| IFT88 | TMEM167B | 0.716182 | 3 | 0 | 3 |
| IFT88 | PBX2 | 0.705871 | 3 | 0 | 3 |
| IFT88 | GDPD1 | 0.696911 | 4 | 0 | 3 |
| IFT88 | MYSM1 | 0.695254 | 3 | 0 | 3 |
| IFT88 | SYTL2 | 0.695033 | 3 | 0 | 3 |
| IFT88 | MTMR10 | 0.693769 | 3 | 0 | 3 |
| IFT88 | WIPF3 | 0.693199 | 3 | 0 | 3 |
| IFT88 | WDR35 | 0.685149 | 6 | 0 | 5 |
| IFT88 | NFATC1 | 0.68472 | 3 | 0 | 3 |
| IFT88 | SLC2A13 | 0.684601 | 3 | 0 | 3 |
| IFT88 | EIF2D | 0.683587 | 5 | 0 | 3 |
| IFT88 | IFT81 | 0.683365 | 8 | 0 | 8 |
| IFT88 | KCND3 | 0.678081 | 3 | 0 | 3 |
| IFT88 | NPHP1 | 0.677135 | 4 | 0 | 4 |
| IFT88 | FAM13C | 0.674227 | 3 | 0 | 3 |
For details and further investigation, click here
