| Full name: WD repeat domain 35 | Alias Symbol: MGC33196|KIAA1336|IFT121|IFTA1 | ||
| Type: protein-coding gene | Cytoband: 2p24.1 | ||
| Entrez ID: 57539 | HGNC ID: HGNC:29250 | Ensembl Gene: ENSG00000118965 | OMIM ID: 613602 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR35 | 57539 | 226889_at | -0.1502 | 0.8599 | |
| GSE26886 | WDR35 | 57539 | 226889_at | 0.5311 | 0.0951 | |
| GSE45670 | WDR35 | 57539 | 226889_at | -0.5071 | 0.0186 | |
| GSE53622 | WDR35 | 57539 | 76241 | -0.4210 | 0.0049 | |
| GSE53624 | WDR35 | 57539 | 76241 | -0.1862 | 0.0963 | |
| GSE63941 | WDR35 | 57539 | 226889_at | -0.9533 | 0.1813 | |
| GSE77861 | WDR35 | 57539 | 226889_at | 0.2620 | 0.1650 | |
| GSE97050 | WDR35 | 57539 | A_33_P3335865 | -0.6715 | 0.1748 | |
| SRP007169 | WDR35 | 57539 | RNAseq | 0.9769 | 0.0443 | |
| SRP008496 | WDR35 | 57539 | RNAseq | 1.5926 | 0.0001 | |
| SRP064894 | WDR35 | 57539 | RNAseq | 0.1710 | 0.4310 | |
| SRP133303 | WDR35 | 57539 | RNAseq | 0.2216 | 0.1178 | |
| SRP159526 | WDR35 | 57539 | RNAseq | 0.6456 | 0.1384 | |
| SRP193095 | WDR35 | 57539 | RNAseq | 0.5801 | 0.0001 | |
| SRP219564 | WDR35 | 57539 | RNAseq | 0.1451 | 0.6762 | |
| TCGA | WDR35 | 57539 | RNAseq | -0.1593 | 0.0581 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by WDR35 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR35 | 57539 | 9 | 2 | 19 | |
| GSE20123 | WDR35 | 57539 | 9 | 2 | 19 | |
| GSE43470 | WDR35 | 57539 | 2 | 0 | 41 | |
| GSE46452 | WDR35 | 57539 | 3 | 4 | 52 | |
| GSE47630 | WDR35 | 57539 | 7 | 0 | 33 | |
| GSE54993 | WDR35 | 57539 | 0 | 7 | 63 | |
| GSE54994 | WDR35 | 57539 | 11 | 0 | 42 | |
| GSE60625 | WDR35 | 57539 | 0 | 3 | 8 | |
| GSE74703 | WDR35 | 57539 | 2 | 0 | 34 | |
| GSE74704 | WDR35 | 57539 | 8 | 2 | 10 | |
| TCGA | WDR35 | 57539 | 36 | 3 | 57 |
Total number of gains: 87; Total number of losses: 23; Total Number of normals: 378.
Somatic mutations of WDR35:
Generating mutation plots.
Highly correlated genes for WDR35:
Showing top 20/738 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR35 | HDAC9 | 0.815224 | 3 | 0 | 3 |
| WDR35 | SORL1 | 0.778481 | 3 | 0 | 3 |
| WDR35 | CSRNP2 | 0.776171 | 4 | 0 | 4 |
| WDR35 | BOD1 | 0.763595 | 3 | 0 | 3 |
| WDR35 | GCLC | 0.762843 | 3 | 0 | 3 |
| WDR35 | BAG2 | 0.759147 | 3 | 0 | 3 |
| WDR35 | NHLRC2 | 0.753495 | 5 | 0 | 5 |
| WDR35 | GATAD2B | 0.746877 | 3 | 0 | 3 |
| WDR35 | BCAS3 | 0.745214 | 3 | 0 | 3 |
| WDR35 | KIAA0040 | 0.737565 | 3 | 0 | 3 |
| WDR35 | DNM1L | 0.737432 | 3 | 0 | 3 |
| WDR35 | KIAA0753 | 0.736013 | 4 | 0 | 4 |
| WDR35 | ESYT1 | 0.73461 | 3 | 0 | 3 |
| WDR35 | ZSCAN21 | 0.731841 | 3 | 0 | 3 |
| WDR35 | SRSF11 | 0.728588 | 3 | 0 | 3 |
| WDR35 | OTUD3 | 0.72448 | 3 | 0 | 3 |
| WDR35 | PRTFDC1 | 0.724384 | 3 | 0 | 3 |
| WDR35 | DNAH14 | 0.720134 | 3 | 0 | 3 |
| WDR35 | IGSF11 | 0.718544 | 3 | 0 | 3 |
| WDR35 | NOM1 | 0.718298 | 3 | 0 | 3 |
For details and further investigation, click here
