| Full name: synaptotagmin like 2 | Alias Symbol: FLJ20163|FLJ21219|KIAA1597|exophilin-4|CHR11SYT|SLP2|SGA72M|MGC102768|PPP1R151 | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 54843 | HGNC ID: HGNC:15585 | Ensembl Gene: ENSG00000137501 | OMIM ID: 612880 |
| Drug and gene relationship at DGIdb | |||
Expression of SYTL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYTL2 | 54843 | 232914_s_at | 0.0363 | 0.9799 | |
| GSE20347 | SYTL2 | 54843 | 220613_s_at | -0.0153 | 0.8197 | |
| GSE23400 | SYTL2 | 54843 | 220613_s_at | -0.0903 | 0.0030 | |
| GSE26886 | SYTL2 | 54843 | 225496_s_at | 0.3775 | 0.1781 | |
| GSE29001 | SYTL2 | 54843 | 220613_s_at | -0.0459 | 0.6830 | |
| GSE38129 | SYTL2 | 54843 | 220613_s_at | -0.0697 | 0.2886 | |
| GSE45670 | SYTL2 | 54843 | 232914_s_at | -1.2975 | 0.0002 | |
| GSE53622 | SYTL2 | 54843 | 156094 | -0.2515 | 0.0861 | |
| GSE53624 | SYTL2 | 54843 | 156094 | -0.3073 | 0.0254 | |
| GSE63941 | SYTL2 | 54843 | 232914_s_at | -1.3744 | 0.4111 | |
| GSE77861 | SYTL2 | 54843 | 232914_s_at | 0.5038 | 0.0078 | |
| GSE97050 | SYTL2 | 54843 | A_23_P53193 | 0.5643 | 0.1316 | |
| SRP007169 | SYTL2 | 54843 | RNAseq | 2.9291 | 0.0002 | |
| SRP008496 | SYTL2 | 54843 | RNAseq | 3.0897 | 0.0000 | |
| SRP064894 | SYTL2 | 54843 | RNAseq | -0.1427 | 0.6404 | |
| SRP133303 | SYTL2 | 54843 | RNAseq | 0.5056 | 0.1084 | |
| SRP159526 | SYTL2 | 54843 | RNAseq | -1.0797 | 0.0017 | |
| SRP193095 | SYTL2 | 54843 | RNAseq | -1.6935 | 0.0016 | |
| SRP219564 | SYTL2 | 54843 | RNAseq | -0.1056 | 0.8059 | |
| TCGA | SYTL2 | 54843 | RNAseq | -1.0005 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 4.
Survival by SYTL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYTL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYTL2 | 54843 | 4 | 9 | 17 | |
| GSE20123 | SYTL2 | 54843 | 4 | 9 | 17 | |
| GSE43470 | SYTL2 | 54843 | 3 | 4 | 36 | |
| GSE46452 | SYTL2 | 54843 | 6 | 24 | 29 | |
| GSE47630 | SYTL2 | 54843 | 2 | 19 | 19 | |
| GSE54993 | SYTL2 | 54843 | 8 | 2 | 60 | |
| GSE54994 | SYTL2 | 54843 | 5 | 19 | 29 | |
| GSE60625 | SYTL2 | 54843 | 0 | 3 | 8 | |
| GSE74703 | SYTL2 | 54843 | 2 | 3 | 31 | |
| GSE74704 | SYTL2 | 54843 | 3 | 6 | 11 | |
| TCGA | SYTL2 | 54843 | 16 | 38 | 42 |
Total number of gains: 53; Total number of losses: 136; Total Number of normals: 299.
Somatic mutations of SYTL2:
Generating mutation plots.
Highly correlated genes for SYTL2:
Showing top 20/440 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYTL2 | KIAA1324L | 0.779431 | 3 | 0 | 3 |
| SYTL2 | SGTB | 0.777373 | 3 | 0 | 3 |
| SYTL2 | SMCR8 | 0.758032 | 3 | 0 | 3 |
| SYTL2 | TAF6 | 0.757787 | 3 | 0 | 3 |
| SYTL2 | ANKIB1 | 0.739118 | 3 | 0 | 3 |
| SYTL2 | MCAM | 0.734276 | 4 | 0 | 4 |
| SYTL2 | INO80D | 0.734027 | 3 | 0 | 3 |
| SYTL2 | RHBDD2 | 0.733113 | 3 | 0 | 3 |
| SYTL2 | FYN | 0.732048 | 5 | 0 | 5 |
| SYTL2 | RPS9 | 0.730582 | 3 | 0 | 3 |
| SYTL2 | L3MBTL3 | 0.729128 | 5 | 0 | 4 |
| SYTL2 | THAP5 | 0.726278 | 3 | 0 | 3 |
| SYTL2 | COL6A2 | 0.722743 | 4 | 0 | 4 |
| SYTL2 | ZNF322 | 0.719705 | 3 | 0 | 3 |
| SYTL2 | C11orf96 | 0.714906 | 3 | 0 | 3 |
| SYTL2 | SLC25A14 | 0.711019 | 4 | 0 | 3 |
| SYTL2 | DDB1 | 0.705541 | 3 | 0 | 3 |
| SYTL2 | PHLDB2 | 0.701455 | 3 | 0 | 3 |
| SYTL2 | CHMP4B | 0.70073 | 3 | 0 | 3 |
| SYTL2 | CCDC102B | 0.699112 | 4 | 0 | 4 |
For details and further investigation, click here
