| Full name: intraflagellar transport 81 | Alias Symbol: CDV-1R|MGC4027 | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 28981 | HGNC ID: HGNC:14313 | Ensembl Gene: ENSG00000122970 | OMIM ID: 605489 |
| Drug and gene relationship at DGIdb | |||
Expression of IFT81:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFT81 | 28981 | 219372_at | -0.2109 | 0.7746 | |
| GSE20347 | IFT81 | 28981 | 219372_at | 0.6345 | 0.0003 | |
| GSE23400 | IFT81 | 28981 | 219372_at | 0.2884 | 0.0000 | |
| GSE26886 | IFT81 | 28981 | 219372_at | 1.1227 | 0.0001 | |
| GSE29001 | IFT81 | 28981 | 219372_at | 0.7682 | 0.0425 | |
| GSE38129 | IFT81 | 28981 | 219372_at | 0.5208 | 0.0090 | |
| GSE45670 | IFT81 | 28981 | 219372_at | -0.4081 | 0.0339 | |
| GSE53622 | IFT81 | 28981 | 26256 | 0.2743 | 0.0132 | |
| GSE53624 | IFT81 | 28981 | 26256 | 0.5011 | 0.0000 | |
| GSE63941 | IFT81 | 28981 | 219372_at | -1.2864 | 0.0080 | |
| GSE77861 | IFT81 | 28981 | 223736_at | -0.2915 | 0.0329 | |
| GSE97050 | IFT81 | 28981 | A_33_P3234989 | -0.1982 | 0.5014 | |
| SRP007169 | IFT81 | 28981 | RNAseq | 1.5323 | 0.0003 | |
| SRP008496 | IFT81 | 28981 | RNAseq | 1.4687 | 0.0000 | |
| SRP064894 | IFT81 | 28981 | RNAseq | 0.2286 | 0.3106 | |
| SRP133303 | IFT81 | 28981 | RNAseq | 0.3021 | 0.0074 | |
| SRP159526 | IFT81 | 28981 | RNAseq | 0.7203 | 0.0193 | |
| SRP193095 | IFT81 | 28981 | RNAseq | 0.5522 | 0.0000 | |
| SRP219564 | IFT81 | 28981 | RNAseq | -0.0225 | 0.9569 | |
| TCGA | IFT81 | 28981 | RNAseq | 0.1513 | 0.0973 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by IFT81 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFT81:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFT81 | 28981 | 5 | 3 | 22 | |
| GSE20123 | IFT81 | 28981 | 5 | 3 | 22 | |
| GSE43470 | IFT81 | 28981 | 2 | 1 | 40 | |
| GSE46452 | IFT81 | 28981 | 9 | 1 | 49 | |
| GSE47630 | IFT81 | 28981 | 9 | 1 | 30 | |
| GSE54993 | IFT81 | 28981 | 0 | 5 | 65 | |
| GSE54994 | IFT81 | 28981 | 4 | 3 | 46 | |
| GSE60625 | IFT81 | 28981 | 0 | 0 | 11 | |
| GSE74703 | IFT81 | 28981 | 2 | 0 | 34 | |
| GSE74704 | IFT81 | 28981 | 2 | 2 | 16 | |
| TCGA | IFT81 | 28981 | 22 | 10 | 64 |
Total number of gains: 60; Total number of losses: 29; Total Number of normals: 399.
Somatic mutations of IFT81:
Generating mutation plots.
Highly correlated genes for IFT81:
Showing top 20/415 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFT81 | PPM1L | 0.774662 | 3 | 0 | 3 |
| IFT81 | TMEM218 | 0.738741 | 3 | 0 | 3 |
| IFT81 | VPS36 | 0.73689 | 3 | 0 | 3 |
| IFT81 | ZYG11B | 0.729564 | 3 | 0 | 3 |
| IFT81 | NTN4 | 0.729067 | 3 | 0 | 3 |
| IFT81 | SLC30A5 | 0.72009 | 3 | 0 | 3 |
| IFT81 | RDH14 | 0.708542 | 3 | 0 | 3 |
| IFT81 | MSRB3 | 0.697787 | 4 | 0 | 4 |
| IFT81 | RNASEH2C | 0.697665 | 3 | 0 | 3 |
| IFT81 | BOD1 | 0.697652 | 5 | 0 | 5 |
| IFT81 | AKAP11 | 0.695553 | 3 | 0 | 3 |
| IFT81 | TMEM129 | 0.695366 | 3 | 0 | 3 |
| IFT81 | MTIF3 | 0.689884 | 3 | 0 | 3 |
| IFT81 | SUFU | 0.689682 | 4 | 0 | 4 |
| IFT81 | IFT88 | 0.683365 | 8 | 0 | 8 |
| IFT81 | MRPL20 | 0.682498 | 3 | 0 | 3 |
| IFT81 | NKAP | 0.680014 | 3 | 0 | 3 |
| IFT81 | FAM8A1 | 0.676015 | 4 | 0 | 3 |
| IFT81 | KCTD7 | 0.671217 | 3 | 0 | 3 |
| IFT81 | TTI2 | 0.671066 | 3 | 0 | 3 |
For details and further investigation, click here
