| Full name: ecdysoneless cell cycle regulator | Alias Symbol: hSGT1|GCR2 | ||
| Type: protein-coding gene | Cytoband: 10q22.2 | ||
| Entrez ID: 11319 | HGNC ID: HGNC:17029 | Ensembl Gene: ENSG00000122882 | OMIM ID: 616464 |
| Drug and gene relationship at DGIdb | |||
Expression of ECD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECD | 11319 | 203013_at | -0.1706 | 0.5898 | |
| GSE20347 | ECD | 11319 | 203013_at | -0.0013 | 0.9932 | |
| GSE23400 | ECD | 11319 | 203013_at | -0.0357 | 0.4613 | |
| GSE26886 | ECD | 11319 | 203013_at | 0.0584 | 0.7990 | |
| GSE29001 | ECD | 11319 | 203013_at | -0.2254 | 0.5310 | |
| GSE38129 | ECD | 11319 | 203013_at | 0.0624 | 0.4823 | |
| GSE45670 | ECD | 11319 | 203013_at | -0.0990 | 0.4364 | |
| GSE53622 | ECD | 11319 | 42882 | -0.3066 | 0.0000 | |
| GSE53624 | ECD | 11319 | 42882 | 0.0044 | 0.9390 | |
| GSE63941 | ECD | 11319 | 203013_at | 0.1781 | 0.6940 | |
| GSE77861 | ECD | 11319 | 203013_at | -0.3099 | 0.0944 | |
| GSE97050 | ECD | 11319 | A_23_P115762 | -0.0579 | 0.7767 | |
| SRP007169 | ECD | 11319 | RNAseq | -0.6357 | 0.0604 | |
| SRP008496 | ECD | 11319 | RNAseq | -0.4485 | 0.0587 | |
| SRP064894 | ECD | 11319 | RNAseq | -0.2317 | 0.0583 | |
| SRP133303 | ECD | 11319 | RNAseq | 0.0739 | 0.4886 | |
| SRP159526 | ECD | 11319 | RNAseq | 0.0092 | 0.9815 | |
| SRP193095 | ECD | 11319 | RNAseq | -0.2250 | 0.0012 | |
| SRP219564 | ECD | 11319 | RNAseq | -0.3349 | 0.1753 | |
| TCGA | ECD | 11319 | RNAseq | 0.0231 | 0.6525 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ECD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ECD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECD | 11319 | 3 | 4 | 23 | |
| GSE20123 | ECD | 11319 | 3 | 3 | 24 | |
| GSE43470 | ECD | 11319 | 1 | 8 | 34 | |
| GSE46452 | ECD | 11319 | 0 | 11 | 48 | |
| GSE47630 | ECD | 11319 | 2 | 14 | 24 | |
| GSE54993 | ECD | 11319 | 7 | 0 | 63 | |
| GSE54994 | ECD | 11319 | 2 | 10 | 41 | |
| GSE60625 | ECD | 11319 | 0 | 0 | 11 | |
| GSE74703 | ECD | 11319 | 1 | 5 | 30 | |
| GSE74704 | ECD | 11319 | 1 | 1 | 18 | |
| TCGA | ECD | 11319 | 11 | 23 | 62 |
Total number of gains: 31; Total number of losses: 79; Total Number of normals: 378.
Somatic mutations of ECD:
Generating mutation plots.
Highly correlated genes for ECD:
Showing top 20/427 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECD | PRKAB1 | 0.827827 | 3 | 0 | 3 |
| ECD | RAB2A | 0.761895 | 3 | 0 | 3 |
| ECD | ZNF214 | 0.758016 | 3 | 0 | 3 |
| ECD | DAAM1 | 0.757355 | 3 | 0 | 3 |
| ECD | THAP4 | 0.755592 | 3 | 0 | 3 |
| ECD | PANK1 | 0.75444 | 3 | 0 | 3 |
| ECD | CAPZA1 | 0.749619 | 3 | 0 | 3 |
| ECD | ZNF518A | 0.747783 | 3 | 0 | 3 |
| ECD | GIN1 | 0.747758 | 3 | 0 | 3 |
| ECD | RBM33 | 0.746117 | 3 | 0 | 3 |
| ECD | SLC35A3 | 0.743551 | 4 | 0 | 4 |
| ECD | NCOR1 | 0.7427 | 3 | 0 | 3 |
| ECD | BARD1 | 0.742214 | 3 | 0 | 3 |
| ECD | RAP1GDS1 | 0.7409 | 3 | 0 | 3 |
| ECD | MIF4GD | 0.739902 | 3 | 0 | 3 |
| ECD | BLOC1S2 | 0.72961 | 3 | 0 | 3 |
| ECD | IFT88 | 0.72952 | 3 | 0 | 3 |
| ECD | PMPCB | 0.729022 | 3 | 0 | 3 |
| ECD | DTWD1 | 0.723612 | 4 | 0 | 3 |
| ECD | FNDC3A | 0.723321 | 3 | 0 | 3 |
For details and further investigation, click here
