| Full name: transmembrane protein 52 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 339456 | HGNC ID: HGNC:27916 | Ensembl Gene: ENSG00000178821 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM52 | 339456 | 230467_at | 0.6278 | 0.1698 | |
| GSE26886 | TMEM52 | 339456 | 230467_at | 0.3820 | 0.0028 | |
| GSE45670 | TMEM52 | 339456 | 230467_at | 0.0498 | 0.7968 | |
| GSE53622 | TMEM52 | 339456 | 42649 | 0.1329 | 0.1639 | |
| GSE53624 | TMEM52 | 339456 | 42649 | -0.2304 | 0.0144 | |
| GSE63941 | TMEM52 | 339456 | 230467_at | 1.1536 | 0.0621 | |
| GSE77861 | TMEM52 | 339456 | 230467_at | -0.1866 | 0.0493 | |
| GSE97050 | TMEM52 | 339456 | A_33_P3274319 | 0.2811 | 0.3405 | |
| SRP159526 | TMEM52 | 339456 | RNAseq | 0.4618 | 0.2818 | |
| TCGA | TMEM52 | 339456 | RNAseq | -0.1059 | 0.6544 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM52 | 339456 | 4 | 7 | 19 | |
| GSE20123 | TMEM52 | 339456 | 4 | 6 | 20 | |
| GSE43470 | TMEM52 | 339456 | 3 | 5 | 35 | |
| GSE46452 | TMEM52 | 339456 | 7 | 1 | 51 | |
| GSE47630 | TMEM52 | 339456 | 8 | 4 | 28 | |
| GSE54993 | TMEM52 | 339456 | 2 | 2 | 66 | |
| GSE54994 | TMEM52 | 339456 | 15 | 2 | 36 | |
| GSE60625 | TMEM52 | 339456 | 0 | 0 | 11 | |
| GSE74703 | TMEM52 | 339456 | 3 | 3 | 30 | |
| GSE74704 | TMEM52 | 339456 | 4 | 0 | 16 | |
| TCGA | TMEM52 | 339456 | 14 | 20 | 62 |
Total number of gains: 64; Total number of losses: 50; Total Number of normals: 374.
Somatic mutations of TMEM52:
Generating mutation plots.
Highly correlated genes for TMEM52:
Showing top 20/171 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM52 | KCNT1 | 0.779171 | 3 | 0 | 3 |
| TMEM52 | SFTPD | 0.774526 | 3 | 0 | 3 |
| TMEM52 | SCARF2 | 0.757909 | 3 | 0 | 3 |
| TMEM52 | ARHGAP22 | 0.756867 | 3 | 0 | 3 |
| TMEM52 | IGFN1 | 0.751005 | 3 | 0 | 3 |
| TMEM52 | FAM71A | 0.750563 | 3 | 0 | 3 |
| TMEM52 | RHBDL1 | 0.73835 | 3 | 0 | 3 |
| TMEM52 | ZSCAN2 | 0.731032 | 3 | 0 | 3 |
| TMEM52 | DHRS2 | 0.729859 | 3 | 0 | 3 |
| TMEM52 | KRT74 | 0.716769 | 4 | 0 | 3 |
| TMEM52 | PMEPA1 | 0.716379 | 3 | 0 | 3 |
| TMEM52 | NTRK1 | 0.715809 | 4 | 0 | 3 |
| TMEM52 | TMEM59L | 0.710269 | 3 | 0 | 3 |
| TMEM52 | WDR83 | 0.708664 | 3 | 0 | 3 |
| TMEM52 | CCDC142 | 0.707958 | 3 | 0 | 3 |
| TMEM52 | SALL3 | 0.707745 | 3 | 0 | 3 |
| TMEM52 | MFSD6L | 0.707533 | 3 | 0 | 3 |
| TMEM52 | GPBAR1 | 0.701557 | 3 | 0 | 3 |
| TMEM52 | NOBOX | 0.701475 | 3 | 0 | 3 |
| TMEM52 | TRIM31 | 0.699091 | 4 | 0 | 4 |
For details and further investigation, click here
