| Full name: forkhead box B1 | Alias Symbol: HFKH-5|FKH5 | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 27023 | HGNC ID: HGNC:3799 | Ensembl Gene: ENSG00000171956 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FOXB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXB1 | 27023 | 208513_at | -0.1473 | 0.5196 | |
| GSE20347 | FOXB1 | 27023 | 208513_at | -0.1688 | 0.0215 | |
| GSE23400 | FOXB1 | 27023 | 208513_at | -0.1321 | 0.0001 | |
| GSE26886 | FOXB1 | 27023 | 208513_at | 0.5783 | 0.0011 | |
| GSE29001 | FOXB1 | 27023 | 208513_at | -0.1874 | 0.0622 | |
| GSE38129 | FOXB1 | 27023 | 208513_at | -0.1203 | 0.0669 | |
| GSE45670 | FOXB1 | 27023 | 208513_at | -0.1552 | 0.1392 | |
| GSE53622 | FOXB1 | 27023 | 140541 | -0.3269 | 0.0071 | |
| GSE53624 | FOXB1 | 27023 | 109211 | 0.3262 | 0.0000 | |
| GSE63941 | FOXB1 | 27023 | 208513_at | 0.3839 | 0.1217 | |
| GSE77861 | FOXB1 | 27023 | 208513_at | -0.1321 | 0.3227 | |
| GSE97050 | FOXB1 | 27023 | A_23_P140527 | 0.1944 | 0.4974 | |
| TCGA | FOXB1 | 27023 | RNAseq | 3.4889 | 0.0004 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FOXB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXB1 | 27023 | 6 | 4 | 20 | |
| GSE20123 | FOXB1 | 27023 | 6 | 3 | 21 | |
| GSE43470 | FOXB1 | 27023 | 4 | 4 | 35 | |
| GSE46452 | FOXB1 | 27023 | 3 | 7 | 49 | |
| GSE47630 | FOXB1 | 27023 | 8 | 10 | 22 | |
| GSE54993 | FOXB1 | 27023 | 5 | 6 | 59 | |
| GSE54994 | FOXB1 | 27023 | 6 | 8 | 39 | |
| GSE60625 | FOXB1 | 27023 | 4 | 0 | 7 | |
| GSE74703 | FOXB1 | 27023 | 4 | 3 | 29 | |
| GSE74704 | FOXB1 | 27023 | 2 | 3 | 15 | |
| TCGA | FOXB1 | 27023 | 10 | 17 | 69 |
Total number of gains: 58; Total number of losses: 65; Total Number of normals: 365.
Somatic mutations of FOXB1:
Generating mutation plots.
Highly correlated genes for FOXB1:
Showing top 20/839 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXB1 | LHX9 | 0.814342 | 3 | 0 | 3 |
| FOXB1 | IGFN1 | 0.804934 | 3 | 0 | 3 |
| FOXB1 | SPACA3 | 0.804462 | 3 | 0 | 3 |
| FOXB1 | NPM2 | 0.793463 | 3 | 0 | 3 |
| FOXB1 | MAPK15 | 0.783441 | 3 | 0 | 3 |
| FOXB1 | POM121L12 | 0.779132 | 3 | 0 | 3 |
| FOXB1 | TMEM179 | 0.776215 | 4 | 0 | 4 |
| FOXB1 | HMGB4 | 0.773658 | 3 | 0 | 3 |
| FOXB1 | FAM131A | 0.767747 | 3 | 0 | 3 |
| FOXB1 | GPC2 | 0.757865 | 3 | 0 | 3 |
| FOXB1 | GYPE | 0.757743 | 3 | 0 | 3 |
| FOXB1 | SUN5 | 0.75354 | 3 | 0 | 3 |
| FOXB1 | TMEM105 | 0.750263 | 3 | 0 | 3 |
| FOXB1 | LRRC46 | 0.743916 | 3 | 0 | 3 |
| FOXB1 | NOBOX | 0.738822 | 3 | 0 | 3 |
| FOXB1 | RASL10B | 0.738741 | 5 | 0 | 5 |
| FOXB1 | FAM222A-AS1 | 0.735695 | 3 | 0 | 3 |
| FOXB1 | ATXN7L2 | 0.732091 | 3 | 0 | 3 |
| FOXB1 | IL21 | 0.731414 | 3 | 0 | 3 |
| FOXB1 | CFC1 | 0.72888 | 3 | 0 | 3 |
For details and further investigation, click here
