| Full name: junctophilin 3 | Alias Symbol: JP-3|CAGL237|HDL2|JP3 | ||
| Type: protein-coding gene | Cytoband: 16q24.2 | ||
| Entrez ID: 57338 | HGNC ID: HGNC:14203 | Ensembl Gene: ENSG00000154118 | OMIM ID: 605268 |
| Drug and gene relationship at DGIdb | |||
Expression of JPH3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | JPH3 | 57338 | 243679_at | 0.1043 | 0.7122 | |
| GSE20347 | JPH3 | 57338 | 220188_at | -0.0448 | 0.4079 | |
| GSE23400 | JPH3 | 57338 | 220188_at | -0.0436 | 0.0740 | |
| GSE26886 | JPH3 | 57338 | 243679_at | 0.1654 | 0.1439 | |
| GSE29001 | JPH3 | 57338 | 220188_at | -0.0150 | 0.9018 | |
| GSE38129 | JPH3 | 57338 | 220188_at | -0.0604 | 0.1819 | |
| GSE45670 | JPH3 | 57338 | 243679_at | -0.0658 | 0.5985 | |
| GSE53622 | JPH3 | 57338 | 63136 | 0.3244 | 0.0042 | |
| GSE53624 | JPH3 | 57338 | 63136 | 0.5254 | 0.0000 | |
| GSE63941 | JPH3 | 57338 | 229294_at | 1.3025 | 0.2617 | |
| GSE77861 | JPH3 | 57338 | 243679_at | -0.0435 | 0.6730 | |
| GSE97050 | JPH3 | 57338 | A_33_P3423721 | -0.2743 | 0.2247 | |
| SRP133303 | JPH3 | 57338 | RNAseq | -0.2169 | 0.5071 | |
| SRP159526 | JPH3 | 57338 | RNAseq | -0.4404 | 0.4858 | |
| TCGA | JPH3 | 57338 | RNAseq | -0.6172 | 0.1250 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by JPH3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of JPH3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | JPH3 | 57338 | 4 | 3 | 23 | |
| GSE20123 | JPH3 | 57338 | 4 | 3 | 23 | |
| GSE43470 | JPH3 | 57338 | 1 | 13 | 29 | |
| GSE46452 | JPH3 | 57338 | 38 | 1 | 20 | |
| GSE47630 | JPH3 | 57338 | 11 | 9 | 20 | |
| GSE54993 | JPH3 | 57338 | 3 | 4 | 63 | |
| GSE54994 | JPH3 | 57338 | 9 | 11 | 33 | |
| GSE60625 | JPH3 | 57338 | 4 | 0 | 7 | |
| GSE74703 | JPH3 | 57338 | 1 | 9 | 26 | |
| GSE74704 | JPH3 | 57338 | 3 | 2 | 15 | |
| TCGA | JPH3 | 57338 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of JPH3:
Generating mutation plots.
Highly correlated genes for JPH3:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| JPH3 | DENND5B | 0.719666 | 3 | 0 | 3 |
| JPH3 | TP53I11 | 0.718042 | 4 | 0 | 3 |
| JPH3 | FAM131B | 0.711837 | 3 | 0 | 3 |
| JPH3 | ZNF343 | 0.70815 | 3 | 0 | 3 |
| JPH3 | HNRNPUL1 | 0.70725 | 3 | 0 | 3 |
| JPH3 | GNAT2 | 0.692077 | 3 | 0 | 3 |
| JPH3 | DIRC1 | 0.689285 | 3 | 0 | 3 |
| JPH3 | UNC119 | 0.687586 | 3 | 0 | 3 |
| JPH3 | ZNF467 | 0.685933 | 5 | 0 | 4 |
| JPH3 | TRIM47 | 0.684116 | 3 | 0 | 3 |
| JPH3 | CNTF | 0.684041 | 3 | 0 | 3 |
| JPH3 | ING1 | 0.68285 | 3 | 0 | 3 |
| JPH3 | ZNF460 | 0.677424 | 3 | 0 | 3 |
| JPH3 | ADAM15 | 0.676925 | 3 | 0 | 3 |
| JPH3 | RAB40AL | 0.672232 | 3 | 0 | 3 |
| JPH3 | RBP4 | 0.665722 | 3 | 0 | 3 |
| JPH3 | HDAC11 | 0.662593 | 5 | 0 | 5 |
| JPH3 | CLCF1 | 0.662446 | 3 | 0 | 3 |
| JPH3 | GTDC1 | 0.66067 | 3 | 0 | 3 |
| JPH3 | PCBP3 | 0.660287 | 5 | 0 | 4 |
For details and further investigation, click here
