| Full name: cardiotrophin like cytokine factor 1 | Alias Symbol: NNT1|BSF3|CLC|NR6|CISS2|BSF-3|NNT-1 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 23529 | HGNC ID: HGNC:17412 | Ensembl Gene: ENSG00000175505 | OMIM ID: 607672 |
| Drug and gene relationship at DGIdb | |||
Expression of CLCF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLCF1 | 23529 | 219500_at | 0.1030 | 0.8046 | |
| GSE20347 | CLCF1 | 23529 | 219500_at | 0.2558 | 0.0048 | |
| GSE23400 | CLCF1 | 23529 | 219500_at | 0.0557 | 0.1898 | |
| GSE26886 | CLCF1 | 23529 | 219500_at | 0.5085 | 0.0007 | |
| GSE29001 | CLCF1 | 23529 | 219500_at | -0.1246 | 0.4464 | |
| GSE38129 | CLCF1 | 23529 | 219500_at | 0.0989 | 0.4513 | |
| GSE45670 | CLCF1 | 23529 | 219500_at | 0.0861 | 0.5742 | |
| GSE53622 | CLCF1 | 23529 | 48985 | 0.7040 | 0.0000 | |
| GSE53624 | CLCF1 | 23529 | 48985 | 0.8529 | 0.0000 | |
| GSE63941 | CLCF1 | 23529 | 219500_at | -0.4228 | 0.0693 | |
| GSE77861 | CLCF1 | 23529 | 219500_at | 0.0177 | 0.8926 | |
| GSE97050 | CLCF1 | 23529 | A_23_P138760 | 0.2260 | 0.4509 | |
| SRP007169 | CLCF1 | 23529 | RNAseq | 0.5701 | 0.4548 | |
| SRP064894 | CLCF1 | 23529 | RNAseq | 0.0094 | 0.9763 | |
| SRP133303 | CLCF1 | 23529 | RNAseq | 0.3245 | 0.1689 | |
| SRP159526 | CLCF1 | 23529 | RNAseq | 0.4453 | 0.4621 | |
| SRP193095 | CLCF1 | 23529 | RNAseq | 1.2626 | 0.0000 | |
| SRP219564 | CLCF1 | 23529 | RNAseq | 0.3131 | 0.5102 | |
| TCGA | CLCF1 | 23529 | RNAseq | -0.0745 | 0.5926 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CLCF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLCF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLCF1 | 23529 | 8 | 4 | 18 | |
| GSE20123 | CLCF1 | 23529 | 8 | 4 | 18 | |
| GSE43470 | CLCF1 | 23529 | 6 | 1 | 36 | |
| GSE46452 | CLCF1 | 23529 | 13 | 3 | 43 | |
| GSE47630 | CLCF1 | 23529 | 8 | 5 | 27 | |
| GSE54993 | CLCF1 | 23529 | 3 | 1 | 66 | |
| GSE54994 | CLCF1 | 23529 | 13 | 4 | 36 | |
| GSE60625 | CLCF1 | 23529 | 0 | 3 | 8 | |
| GSE74703 | CLCF1 | 23529 | 4 | 0 | 32 | |
| GSE74704 | CLCF1 | 23529 | 7 | 2 | 11 | |
| TCGA | CLCF1 | 23529 | 28 | 8 | 60 |
Total number of gains: 98; Total number of losses: 35; Total Number of normals: 355.
Somatic mutations of CLCF1:
Generating mutation plots.
Highly correlated genes for CLCF1:
Showing top 20/427 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLCF1 | CDH7 | 0.743359 | 3 | 0 | 3 |
| CLCF1 | IL17F | 0.742634 | 3 | 0 | 3 |
| CLCF1 | MAP3K19 | 0.725403 | 3 | 0 | 3 |
| CLCF1 | FAM153A | 0.71166 | 4 | 0 | 4 |
| CLCF1 | ASCL1 | 0.688981 | 3 | 0 | 3 |
| CLCF1 | SCUBE1 | 0.677357 | 3 | 0 | 3 |
| CLCF1 | ZNF771 | 0.67509 | 4 | 0 | 4 |
| CLCF1 | HBQ1 | 0.671247 | 4 | 0 | 4 |
| CLCF1 | CDH2 | 0.66461 | 3 | 0 | 3 |
| CLCF1 | ABRA | 0.663031 | 3 | 0 | 3 |
| CLCF1 | JPH3 | 0.662446 | 3 | 0 | 3 |
| CLCF1 | ADAMTS1 | 0.658943 | 3 | 0 | 3 |
| CLCF1 | SOD3 | 0.657185 | 3 | 0 | 3 |
| CLCF1 | NFE4 | 0.656034 | 3 | 0 | 3 |
| CLCF1 | ASCL5 | 0.654624 | 3 | 0 | 3 |
| CLCF1 | BMP15 | 0.653891 | 3 | 0 | 3 |
| CLCF1 | SLC18A3 | 0.652444 | 3 | 0 | 3 |
| CLCF1 | SERINC2 | 0.651117 | 3 | 0 | 3 |
| CLCF1 | TP53I11 | 0.646247 | 4 | 0 | 4 |
| CLCF1 | ADM2 | 0.642232 | 5 | 0 | 5 |
For details and further investigation, click here
