UNC119

 

Full name: unc-119 lipid binding chaperone Alias Symbol: HRG4|POC7|POC7A
Type: protein-coding gene Cytoband: 17q11.2
Entrez ID: 9094 HGNC ID: HGNC:12565 Ensembl Gene: ENSG00000109103 OMIM ID: 604011
Drug and gene relationship at DGIdb

 

Expression of UNC119:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UNC119 9094 203271_s_at 0.3431 0.1601
GSE20347 UNC119 9094 203271_s_at 0.3966 0.0001
GSE23400 UNC119 9094 203271_s_at 0.0554 0.1684
GSE26886 UNC119 9094 203271_s_at 0.4245 0.0518
GSE29001 UNC119 9094 203271_s_at 0.0367 0.8511
GSE38129 UNC119 9094 203271_s_at 0.3360 0.0002
GSE45670 UNC119 9094 203271_s_at 0.3653 0.0051
GSE53622 UNC119 9094 19001 0.6356 0.0000
GSE53624 UNC119 9094 19001 0.5650 0.0000
GSE63941 UNC119 9094 203271_s_at 0.3650 0.3615
GSE77861 UNC119 9094 203271_s_at 0.4400 0.0395
GSE97050 UNC119 9094 A_23_P49842 0.1245 0.6195
SRP007169 UNC119 9094 RNAseq -0.1412 0.8052
SRP008496 UNC119 9094 RNAseq 0.0164 0.9618
SRP064894 UNC119 9094 RNAseq 0.5182 0.0386
SRP133303 UNC119 9094 RNAseq 0.3025 0.1325
SRP159526 UNC119 9094 RNAseq 0.7897 0.0002
SRP193095 UNC119 9094 RNAseq 0.4943 0.0002
SRP219564 UNC119 9094 RNAseq 0.2061 0.5599
TCGA UNC119 9094 RNAseq 0.2579 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by UNC119 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of UNC119:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UNC119 9094 9 1 20
GSE20123 UNC119 9094 9 1 20
GSE43470 UNC119 9094 0 1 42
GSE46452 UNC119 9094 33 1 25
GSE47630 UNC119 9094 7 1 32
GSE54993 UNC119 9094 2 3 65
GSE54994 UNC119 9094 7 6 40
GSE60625 UNC119 9094 4 0 7
GSE74703 UNC119 9094 0 1 35
GSE74704 UNC119 9094 7 1 12
TCGA UNC119 9094 21 10 65

Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.  


 

Somatic mutations of UNC119:

 

Generating mutation plots.

 

Highly correlated genes for UNC119:

 

Showing top 20/1156 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UNC119ZCCHC30.764494303
UNC119SENP30.736015606
UNC119ZDHHC40.732027303
UNC119RAB340.725409303
UNC119CATSPER10.721628303
UNC119NF10.717755303
UNC119CUTA0.711749303
UNC119DHX360.708786404
UNC119NUMA10.707064303
UNC119HELZ0.695515303
UNC119ZNF7640.691022303
UNC119XRCC10.68899303
UNC119JPH30.687586303
UNC119LRTOMT0.684194303
UNC119PYCR20.681712403
UNC119ANAPC130.679356404
UNC119PTCD10.678783303
UNC119RELL20.67165303
UNC119OAF0.671624403
UNC119GNS0.668822404

For details and further investigation, click here