| Full name: katanin catalytic subunit A1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 11104 | HGNC ID: HGNC:6216 | Ensembl Gene: ENSG00000186625 | OMIM ID: 606696 |
| Drug and gene relationship at DGIdb | |||
Expression of KATNA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KATNA1 | 11104 | 205526_s_at | 0.3484 | 0.3685 | |
| GSE20347 | KATNA1 | 11104 | 205526_s_at | 0.2191 | 0.1715 | |
| GSE23400 | KATNA1 | 11104 | 205526_s_at | 0.1690 | 0.0088 | |
| GSE26886 | KATNA1 | 11104 | 205526_s_at | 0.3464 | 0.0374 | |
| GSE29001 | KATNA1 | 11104 | 205526_s_at | 0.3089 | 0.3101 | |
| GSE38129 | KATNA1 | 11104 | 205526_s_at | 0.3322 | 0.0084 | |
| GSE45670 | KATNA1 | 11104 | 205526_s_at | 0.0265 | 0.8622 | |
| GSE53622 | KATNA1 | 11104 | 134395 | 0.0236 | 0.7859 | |
| GSE53624 | KATNA1 | 11104 | 134395 | 0.1792 | 0.0075 | |
| GSE63941 | KATNA1 | 11104 | 205526_s_at | -0.3636 | 0.3179 | |
| GSE77861 | KATNA1 | 11104 | 205526_s_at | 0.3160 | 0.1175 | |
| GSE97050 | KATNA1 | 11104 | A_23_P113803 | -0.0676 | 0.7878 | |
| SRP007169 | KATNA1 | 11104 | RNAseq | -0.1441 | 0.6675 | |
| SRP008496 | KATNA1 | 11104 | RNAseq | 0.1724 | 0.4252 | |
| SRP064894 | KATNA1 | 11104 | RNAseq | 0.2059 | 0.1048 | |
| SRP133303 | KATNA1 | 11104 | RNAseq | 0.1625 | 0.2796 | |
| SRP159526 | KATNA1 | 11104 | RNAseq | -0.0217 | 0.9017 | |
| SRP193095 | KATNA1 | 11104 | RNAseq | -0.1633 | 0.0705 | |
| SRP219564 | KATNA1 | 11104 | RNAseq | -0.4193 | 0.0930 | |
| TCGA | KATNA1 | 11104 | RNAseq | 0.1476 | 0.0168 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KATNA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KATNA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KATNA1 | 11104 | 2 | 4 | 24 | |
| GSE20123 | KATNA1 | 11104 | 1 | 3 | 26 | |
| GSE43470 | KATNA1 | 11104 | 4 | 0 | 39 | |
| GSE46452 | KATNA1 | 11104 | 3 | 10 | 46 | |
| GSE47630 | KATNA1 | 11104 | 9 | 4 | 27 | |
| GSE54993 | KATNA1 | 11104 | 3 | 2 | 65 | |
| GSE54994 | KATNA1 | 11104 | 8 | 8 | 37 | |
| GSE60625 | KATNA1 | 11104 | 0 | 1 | 10 | |
| GSE74703 | KATNA1 | 11104 | 4 | 0 | 32 | |
| GSE74704 | KATNA1 | 11104 | 0 | 1 | 19 | |
| TCGA | KATNA1 | 11104 | 11 | 21 | 64 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of KATNA1:
Generating mutation plots.
Highly correlated genes for KATNA1:
Showing top 20/1192 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KATNA1 | CENPBD1 | 0.808035 | 3 | 0 | 3 |
| KATNA1 | ACBD5 | 0.763523 | 3 | 0 | 3 |
| KATNA1 | CYB5D1 | 0.762413 | 3 | 0 | 3 |
| KATNA1 | CPNE8 | 0.761909 | 3 | 0 | 3 |
| KATNA1 | PET117 | 0.758768 | 3 | 0 | 3 |
| KATNA1 | VMA21 | 0.740342 | 3 | 0 | 3 |
| KATNA1 | UHRF1BP1L | 0.724744 | 4 | 0 | 4 |
| KATNA1 | UHRF1BP1 | 0.7229 | 4 | 0 | 3 |
| KATNA1 | CAMKK2 | 0.72162 | 3 | 0 | 3 |
| KATNA1 | CGRRF1 | 0.72071 | 3 | 0 | 3 |
| KATNA1 | SEC22A | 0.720224 | 5 | 0 | 4 |
| KATNA1 | AGPAT5 | 0.717738 | 4 | 0 | 3 |
| KATNA1 | TCP1 | 0.710213 | 3 | 0 | 3 |
| KATNA1 | PRPF38A | 0.708606 | 3 | 0 | 3 |
| KATNA1 | EFNA1 | 0.705895 | 3 | 0 | 3 |
| KATNA1 | SRI | 0.702621 | 5 | 0 | 5 |
| KATNA1 | MAPKAPK2 | 0.702051 | 3 | 0 | 3 |
| KATNA1 | HERPUD2 | 0.700467 | 3 | 0 | 3 |
| KATNA1 | ASF1A | 0.700426 | 4 | 0 | 3 |
| KATNA1 | MRPS26 | 0.69988 | 3 | 0 | 3 |
For details and further investigation, click here
