| Full name: 1-acylglycerol-3-phosphate O-acyltransferase 5 | Alias Symbol: FLJ11210|LPAAT-e|LPAAT-epsilon | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 55326 | HGNC ID: HGNC:20886 | Ensembl Gene: ENSG00000155189 | OMIM ID: 614796 |
| Drug and gene relationship at DGIdb | |||
Expression of AGPAT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGPAT5 | 55326 | 218096_at | 0.8571 | 0.1168 | |
| GSE20347 | AGPAT5 | 55326 | 218096_at | 0.4086 | 0.1079 | |
| GSE23400 | AGPAT5 | 55326 | 218096_at | 0.6081 | 0.0000 | |
| GSE26886 | AGPAT5 | 55326 | 218096_at | -0.3703 | 0.0620 | |
| GSE29001 | AGPAT5 | 55326 | 218096_at | 0.4792 | 0.1677 | |
| GSE38129 | AGPAT5 | 55326 | 218096_at | 0.6438 | 0.0022 | |
| GSE45670 | AGPAT5 | 55326 | 218096_at | 0.5288 | 0.0152 | |
| GSE63941 | AGPAT5 | 55326 | 218096_at | 1.1555 | 0.0486 | |
| GSE77861 | AGPAT5 | 55326 | 218096_at | 0.8707 | 0.1036 | |
| GSE97050 | AGPAT5 | 55326 | A_33_P3217218 | 0.1027 | 0.6463 | |
| SRP007169 | AGPAT5 | 55326 | RNAseq | 1.3717 | 0.0155 | |
| SRP008496 | AGPAT5 | 55326 | RNAseq | 1.3036 | 0.0004 | |
| SRP064894 | AGPAT5 | 55326 | RNAseq | 0.2177 | 0.3140 | |
| SRP133303 | AGPAT5 | 55326 | RNAseq | -0.0693 | 0.7040 | |
| SRP159526 | AGPAT5 | 55326 | RNAseq | 0.0698 | 0.8245 | |
| SRP193095 | AGPAT5 | 55326 | RNAseq | -0.1833 | 0.3106 | |
| SRP219564 | AGPAT5 | 55326 | RNAseq | 0.1828 | 0.6875 | |
| TCGA | AGPAT5 | 55326 | RNAseq | 0.0720 | 0.2981 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by AGPAT5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of AGPAT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGPAT5 | 55326 | 4 | 11 | 15 | |
| GSE20123 | AGPAT5 | 55326 | 4 | 11 | 15 | |
| GSE43470 | AGPAT5 | 55326 | 4 | 10 | 29 | |
| GSE46452 | AGPAT5 | 55326 | 12 | 14 | 33 | |
| GSE47630 | AGPAT5 | 55326 | 9 | 7 | 24 | |
| GSE54993 | AGPAT5 | 55326 | 3 | 14 | 53 | |
| GSE54994 | AGPAT5 | 55326 | 9 | 19 | 25 | |
| GSE60625 | AGPAT5 | 55326 | 3 | 0 | 8 | |
| GSE74703 | AGPAT5 | 55326 | 4 | 8 | 24 | |
| GSE74704 | AGPAT5 | 55326 | 3 | 7 | 10 | |
| TCGA | AGPAT5 | 55326 | 13 | 40 | 43 |
Total number of gains: 68; Total number of losses: 141; Total Number of normals: 279.
Somatic mutations of AGPAT5:
Generating mutation plots.
Highly correlated genes for AGPAT5:
Showing top 20/904 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGPAT5 | SMCR8 | 0.80711 | 3 | 0 | 3 |
| AGPAT5 | SLC39A10 | 0.79714 | 3 | 0 | 3 |
| AGPAT5 | CENPBD1 | 0.791359 | 3 | 0 | 3 |
| AGPAT5 | RTTN | 0.765208 | 3 | 0 | 3 |
| AGPAT5 | TMEM170A | 0.758294 | 3 | 0 | 3 |
| AGPAT5 | EFHC1 | 0.748809 | 3 | 0 | 3 |
| AGPAT5 | RIOK1 | 0.744724 | 3 | 0 | 3 |
| AGPAT5 | LRRC58 | 0.744298 | 3 | 0 | 3 |
| AGPAT5 | ZNF778 | 0.730172 | 3 | 0 | 3 |
| AGPAT5 | EARS2 | 0.728216 | 3 | 0 | 3 |
| AGPAT5 | ZDHHC16 | 0.727417 | 4 | 0 | 4 |
| AGPAT5 | ZBTB9 | 0.723895 | 4 | 0 | 4 |
| AGPAT5 | LIPA | 0.722006 | 3 | 0 | 3 |
| AGPAT5 | METTL23 | 0.721945 | 4 | 0 | 4 |
| AGPAT5 | KATNA1 | 0.717738 | 4 | 0 | 3 |
| AGPAT5 | AGMAT | 0.717428 | 3 | 0 | 3 |
| AGPAT5 | COPA | 0.714501 | 3 | 0 | 3 |
| AGPAT5 | C8orf76 | 0.711512 | 4 | 0 | 4 |
| AGPAT5 | PGM3 | 0.708283 | 3 | 0 | 3 |
| AGPAT5 | WDR5 | 0.706363 | 4 | 0 | 4 |
For details and further investigation, click here
