| Full name: sorcin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q21.12 | ||
| Entrez ID: 6717 | HGNC ID: HGNC:11292 | Ensembl Gene: ENSG00000075142 | OMIM ID: 182520 |
| Drug and gene relationship at DGIdb | |||
Expression of SRI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRI | 6717 | 208921_s_at | 0.1919 | 0.7638 | |
| GSE20347 | SRI | 6717 | 208921_s_at | 0.0698 | 0.7780 | |
| GSE23400 | SRI | 6717 | 208921_s_at | 0.1412 | 0.0548 | |
| GSE26886 | SRI | 6717 | 208921_s_at | 0.4675 | 0.0122 | |
| GSE29001 | SRI | 6717 | 208921_s_at | -0.0816 | 0.8717 | |
| GSE38129 | SRI | 6717 | 208921_s_at | 0.2080 | 0.1956 | |
| GSE45670 | SRI | 6717 | 208921_s_at | -0.0109 | 0.9494 | |
| GSE53622 | SRI | 6717 | 91050 | -0.5283 | 0.0000 | |
| GSE53624 | SRI | 6717 | 91050 | -0.8445 | 0.0000 | |
| GSE63941 | SRI | 6717 | 208921_s_at | 0.0846 | 0.9236 | |
| GSE77861 | SRI | 6717 | 208921_s_at | 0.0429 | 0.9153 | |
| GSE97050 | SRI | 6717 | A_23_P59718 | -0.3056 | 0.2579 | |
| SRP007169 | SRI | 6717 | RNAseq | -0.9319 | 0.0120 | |
| SRP008496 | SRI | 6717 | RNAseq | -0.6739 | 0.0052 | |
| SRP064894 | SRI | 6717 | RNAseq | 0.1491 | 0.4721 | |
| SRP133303 | SRI | 6717 | RNAseq | 0.3173 | 0.1646 | |
| SRP159526 | SRI | 6717 | RNAseq | -0.1834 | 0.5003 | |
| SRP193095 | SRI | 6717 | RNAseq | -0.2525 | 0.2344 | |
| SRP219564 | SRI | 6717 | RNAseq | 0.4989 | 0.0704 | |
| TCGA | SRI | 6717 | RNAseq | 0.0417 | 0.5313 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SRI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SRI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRI | 6717 | 12 | 1 | 17 | |
| GSE20123 | SRI | 6717 | 12 | 1 | 17 | |
| GSE43470 | SRI | 6717 | 5 | 1 | 37 | |
| GSE46452 | SRI | 6717 | 12 | 0 | 47 | |
| GSE47630 | SRI | 6717 | 8 | 2 | 30 | |
| GSE54993 | SRI | 6717 | 2 | 7 | 61 | |
| GSE54994 | SRI | 6717 | 17 | 2 | 34 | |
| GSE60625 | SRI | 6717 | 0 | 0 | 11 | |
| GSE74703 | SRI | 6717 | 4 | 1 | 31 | |
| GSE74704 | SRI | 6717 | 8 | 1 | 11 | |
| TCGA | SRI | 6717 | 53 | 4 | 39 |
Total number of gains: 133; Total number of losses: 20; Total Number of normals: 335.
Somatic mutations of SRI:
Generating mutation plots.
Highly correlated genes for SRI:
Showing top 20/489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRI | PNKD | 0.778132 | 3 | 0 | 3 |
| SRI | ICK | 0.774217 | 3 | 0 | 3 |
| SRI | FNTA | 0.749887 | 3 | 0 | 3 |
| SRI | USP28 | 0.747667 | 3 | 0 | 3 |
| SRI | POLRMT | 0.742748 | 3 | 0 | 3 |
| SRI | WTIP | 0.732523 | 3 | 0 | 3 |
| SRI | RAD18 | 0.729456 | 3 | 0 | 3 |
| SRI | COX6A1 | 0.728632 | 3 | 0 | 3 |
| SRI | SBF2 | 0.723379 | 3 | 0 | 3 |
| SRI | COA5 | 0.720453 | 3 | 0 | 3 |
| SRI | CCNG1 | 0.71733 | 3 | 0 | 3 |
| SRI | RNFT2 | 0.714333 | 3 | 0 | 3 |
| SRI | RPS14 | 0.712884 | 3 | 0 | 3 |
| SRI | WBP11 | 0.71194 | 3 | 0 | 3 |
| SRI | MSRA | 0.704217 | 3 | 0 | 3 |
| SRI | HP1BP3 | 0.703438 | 3 | 0 | 3 |
| SRI | KATNA1 | 0.702621 | 5 | 0 | 5 |
| SRI | HPS3 | 0.702279 | 4 | 0 | 4 |
| SRI | ASH2L | 0.701389 | 4 | 0 | 3 |
| SRI | RERG | 0.699116 | 4 | 0 | 4 |
For details and further investigation, click here
