| Full name: t-complex 1 | Alias Symbol: D6S230E|CCT1|Ccta | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 6950 | HGNC ID: HGNC:11655 | Ensembl Gene: ENSG00000120438 | OMIM ID: 186980 |
| Drug and gene relationship at DGIdb | |||
Expression of TCP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TCP1 | 6950 | 61837 | 0.3807 | 0.0001 | |
| GSE53624 | TCP1 | 6950 | 61837 | 0.5673 | 0.0000 | |
| GSE97050 | TCP1 | 6950 | A_32_P456537 | 0.5586 | 0.1377 | |
| SRP007169 | TCP1 | 6950 | RNAseq | 0.0862 | 0.7890 | |
| SRP008496 | TCP1 | 6950 | RNAseq | -0.2431 | 0.2908 | |
| SRP064894 | TCP1 | 6950 | RNAseq | 0.3365 | 0.0414 | |
| SRP133303 | TCP1 | 6950 | RNAseq | 0.5452 | 0.0012 | |
| SRP159526 | TCP1 | 6950 | RNAseq | 0.4106 | 0.0510 | |
| SRP193095 | TCP1 | 6950 | RNAseq | 0.1468 | 0.2626 | |
| SRP219564 | TCP1 | 6950 | RNAseq | -0.0041 | 0.9900 | |
| TCGA | TCP1 | 6950 | RNAseq | 0.1216 | 0.0056 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TCP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCP1 | 6950 | 1 | 5 | 24 | |
| GSE20123 | TCP1 | 6950 | 1 | 4 | 25 | |
| GSE43470 | TCP1 | 6950 | 4 | 0 | 39 | |
| GSE46452 | TCP1 | 6950 | 3 | 10 | 46 | |
| GSE47630 | TCP1 | 6950 | 9 | 4 | 27 | |
| GSE54993 | TCP1 | 6950 | 3 | 2 | 65 | |
| GSE54994 | TCP1 | 6950 | 8 | 8 | 37 | |
| GSE60625 | TCP1 | 6950 | 0 | 1 | 10 | |
| GSE74703 | TCP1 | 6950 | 4 | 0 | 32 | |
| GSE74704 | TCP1 | 6950 | 0 | 2 | 18 | |
| TCGA | TCP1 | 6950 | 13 | 22 | 61 |
Total number of gains: 46; Total number of losses: 58; Total Number of normals: 384.
Somatic mutations of TCP1:
Generating mutation plots.
Highly correlated genes for TCP1:
Showing top 20/102 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCP1 | ACD | 0.762262 | 3 | 0 | 3 |
| TCP1 | HAUS1 | 0.737945 | 3 | 0 | 3 |
| TCP1 | DCAF7 | 0.734993 | 3 | 0 | 3 |
| TCP1 | NUDCD1 | 0.732908 | 3 | 0 | 3 |
| TCP1 | CCT8 | 0.720121 | 3 | 0 | 3 |
| TCP1 | TAF6 | 0.715332 | 3 | 0 | 3 |
| TCP1 | NEDD1 | 0.714949 | 3 | 0 | 3 |
| TCP1 | KIF24 | 0.71474 | 3 | 0 | 3 |
| TCP1 | TFAM | 0.710525 | 3 | 0 | 3 |
| TCP1 | TBPL1 | 0.710239 | 4 | 0 | 4 |
| TCP1 | KATNA1 | 0.710213 | 3 | 0 | 3 |
| TCP1 | NUP107 | 0.70702 | 4 | 0 | 3 |
| TCP1 | ATIC | 0.706384 | 3 | 0 | 3 |
| TCP1 | METTL16 | 0.706139 | 3 | 0 | 3 |
| TCP1 | HAUS6 | 0.702609 | 3 | 0 | 3 |
| TCP1 | POLR3F | 0.700737 | 3 | 0 | 3 |
| TCP1 | HDAC2 | 0.698385 | 4 | 0 | 4 |
| TCP1 | LSM2 | 0.698264 | 3 | 0 | 3 |
| TCP1 | TTC26 | 0.694778 | 3 | 0 | 3 |
| TCP1 | MINPP1 | 0.693479 | 3 | 0 | 3 |
For details and further investigation, click here
