| Full name: RNA binding motif protein 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.1-q23.2 | ||
| Entrez ID: 10179 | HGNC ID: HGNC:9904 | Ensembl Gene: ENSG00000076053 | OMIM ID: 612413 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBM7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM7 | 10179 | 218379_at | -0.1756 | 0.6336 | |
| GSE20347 | RBM7 | 10179 | 218379_at | -0.2925 | 0.1403 | |
| GSE23400 | RBM7 | 10179 | 218379_at | 0.0476 | 0.4466 | |
| GSE26886 | RBM7 | 10179 | 218379_at | -1.0915 | 0.0000 | |
| GSE29001 | RBM7 | 10179 | 218379_at | -0.2028 | 0.7225 | |
| GSE38129 | RBM7 | 10179 | 218379_at | -0.2384 | 0.1568 | |
| GSE45670 | RBM7 | 10179 | 218379_at | 0.1312 | 0.3345 | |
| GSE53622 | RBM7 | 10179 | 46588 | -0.2793 | 0.0018 | |
| GSE53624 | RBM7 | 10179 | 46588 | -0.4064 | 0.0113 | |
| GSE63941 | RBM7 | 10179 | 218379_at | -0.0420 | 0.9294 | |
| GSE77861 | RBM7 | 10179 | 218379_at | -0.2450 | 0.4471 | |
| GSE97050 | RBM7 | 10179 | A_23_P138975 | -0.1198 | 0.6270 | |
| SRP007169 | RBM7 | 10179 | RNAseq | -0.5426 | 0.1608 | |
| SRP008496 | RBM7 | 10179 | RNAseq | -0.4673 | 0.0370 | |
| SRP064894 | RBM7 | 10179 | RNAseq | -0.2234 | 0.1918 | |
| SRP133303 | RBM7 | 10179 | RNAseq | -0.0725 | 0.6311 | |
| SRP159526 | RBM7 | 10179 | RNAseq | -0.3306 | 0.3283 | |
| SRP193095 | RBM7 | 10179 | RNAseq | -0.6723 | 0.0000 | |
| SRP219564 | RBM7 | 10179 | RNAseq | -0.5345 | 0.0361 | |
| TCGA | RBM7 | 10179 | RNAseq | -0.1602 | 0.0021 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RBM7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM7 | 10179 | 0 | 13 | 17 | |
| GSE20123 | RBM7 | 10179 | 0 | 13 | 17 | |
| GSE43470 | RBM7 | 10179 | 2 | 7 | 34 | |
| GSE46452 | RBM7 | 10179 | 3 | 26 | 30 | |
| GSE47630 | RBM7 | 10179 | 2 | 19 | 19 | |
| GSE54993 | RBM7 | 10179 | 10 | 0 | 60 | |
| GSE54994 | RBM7 | 10179 | 5 | 19 | 29 | |
| GSE60625 | RBM7 | 10179 | 0 | 3 | 8 | |
| GSE74703 | RBM7 | 10179 | 1 | 5 | 30 | |
| GSE74704 | RBM7 | 10179 | 0 | 9 | 11 | |
| TCGA | RBM7 | 10179 | 6 | 49 | 41 |
Total number of gains: 29; Total number of losses: 163; Total Number of normals: 296.
Somatic mutations of RBM7:
Generating mutation plots.
Highly correlated genes for RBM7:
Showing top 20/863 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM7 | NUP54 | 0.787074 | 3 | 0 | 3 |
| RBM7 | FAM98B | 0.784079 | 3 | 0 | 3 |
| RBM7 | HDAC3 | 0.780296 | 3 | 0 | 3 |
| RBM7 | FBXO9 | 0.769509 | 3 | 0 | 3 |
| RBM7 | PKN2 | 0.768954 | 3 | 0 | 3 |
| RBM7 | ANKRD28 | 0.768385 | 3 | 0 | 3 |
| RBM7 | EIF3I | 0.767658 | 3 | 0 | 3 |
| RBM7 | NSMCE4A | 0.76729 | 4 | 0 | 4 |
| RBM7 | GSPT1 | 0.765563 | 3 | 0 | 3 |
| RBM7 | RNF111 | 0.761106 | 5 | 0 | 5 |
| RBM7 | PPP2R5E | 0.759708 | 3 | 0 | 3 |
| RBM7 | BBS7 | 0.757945 | 3 | 0 | 3 |
| RBM7 | SENP8 | 0.751749 | 5 | 0 | 5 |
| RBM7 | WDR92 | 0.748606 | 3 | 0 | 3 |
| RBM7 | NR2C2 | 0.738676 | 4 | 0 | 4 |
| RBM7 | RHBDD1 | 0.732877 | 3 | 0 | 3 |
| RBM7 | EXOC4 | 0.732433 | 3 | 0 | 3 |
| RBM7 | OGFRL1 | 0.72928 | 4 | 0 | 3 |
| RBM7 | PI4K2B | 0.727967 | 3 | 0 | 3 |
| RBM7 | CUL3 | 0.721549 | 3 | 0 | 3 |
For details and further investigation, click here
