| Full name: butyrophilin subfamily 2 member A1 | Alias Symbol: BT2.1|BTF1|BTN2.1 | ||
| Type: protein-coding gene | Cytoband: 6p22.2 | ||
| Entrez ID: 11120 | HGNC ID: HGNC:1136 | Ensembl Gene: ENSG00000112763 | OMIM ID: 613590 |
| Drug and gene relationship at DGIdb | |||
Expression of BTN2A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTN2A1 | 11120 | 203944_x_at | 0.1030 | 0.8596 | |
| GSE20347 | BTN2A1 | 11120 | 203944_x_at | 0.3287 | 0.0464 | |
| GSE23400 | BTN2A1 | 11120 | 203944_x_at | 0.1696 | 0.0037 | |
| GSE26886 | BTN2A1 | 11120 | 203944_x_at | 0.3711 | 0.1936 | |
| GSE29001 | BTN2A1 | 11120 | 203944_x_at | 0.3335 | 0.0758 | |
| GSE38129 | BTN2A1 | 11120 | 203944_x_at | 0.1515 | 0.2586 | |
| GSE45670 | BTN2A1 | 11120 | 203944_x_at | 0.1116 | 0.5527 | |
| GSE53622 | BTN2A1 | 11120 | 5188 | 0.1481 | 0.0472 | |
| GSE53624 | BTN2A1 | 11120 | 71816 | 0.2248 | 0.1426 | |
| GSE63941 | BTN2A1 | 11120 | 203944_x_at | -0.7163 | 0.0583 | |
| GSE77861 | BTN2A1 | 11120 | 203944_x_at | 0.0591 | 0.8202 | |
| GSE97050 | BTN2A1 | 11120 | A_33_P3332885 | 0.1267 | 0.5599 | |
| SRP007169 | BTN2A1 | 11120 | RNAseq | 1.4562 | 0.0085 | |
| SRP008496 | BTN2A1 | 11120 | RNAseq | 1.2749 | 0.0057 | |
| SRP064894 | BTN2A1 | 11120 | RNAseq | 0.1878 | 0.2377 | |
| SRP133303 | BTN2A1 | 11120 | RNAseq | 0.0780 | 0.4967 | |
| SRP159526 | BTN2A1 | 11120 | RNAseq | -0.3567 | 0.0991 | |
| SRP193095 | BTN2A1 | 11120 | RNAseq | 0.1043 | 0.4436 | |
| SRP219564 | BTN2A1 | 11120 | RNAseq | -0.0459 | 0.8947 | |
| TCGA | BTN2A1 | 11120 | RNAseq | -0.0480 | 0.4120 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by BTN2A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTN2A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTN2A1 | 11120 | 4 | 2 | 24 | |
| GSE20123 | BTN2A1 | 11120 | 4 | 2 | 24 | |
| GSE43470 | BTN2A1 | 11120 | 5 | 0 | 38 | |
| GSE46452 | BTN2A1 | 11120 | 1 | 9 | 49 | |
| GSE47630 | BTN2A1 | 11120 | 8 | 5 | 27 | |
| GSE54993 | BTN2A1 | 11120 | 1 | 1 | 68 | |
| GSE54994 | BTN2A1 | 11120 | 10 | 4 | 39 | |
| GSE60625 | BTN2A1 | 11120 | 0 | 1 | 10 | |
| GSE74703 | BTN2A1 | 11120 | 5 | 0 | 31 | |
| GSE74704 | BTN2A1 | 11120 | 0 | 1 | 19 | |
| TCGA | BTN2A1 | 11120 | 15 | 21 | 60 |
Total number of gains: 53; Total number of losses: 46; Total Number of normals: 389.
Somatic mutations of BTN2A1:
Generating mutation plots.
Highly correlated genes for BTN2A1:
Showing top 20/480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTN2A1 | GOLGA3 | 0.781934 | 3 | 0 | 3 |
| BTN2A1 | ZNF397 | 0.740928 | 4 | 0 | 4 |
| BTN2A1 | KBTBD8 | 0.731565 | 3 | 0 | 3 |
| BTN2A1 | VPS41 | 0.723409 | 3 | 0 | 3 |
| BTN2A1 | UBTD2 | 0.719985 | 3 | 0 | 3 |
| BTN2A1 | TMEM200A | 0.719834 | 4 | 0 | 4 |
| BTN2A1 | CEP44 | 0.710042 | 4 | 0 | 4 |
| BTN2A1 | SFR1 | 0.707178 | 4 | 0 | 4 |
| BTN2A1 | CAPZA2 | 0.707018 | 3 | 0 | 3 |
| BTN2A1 | ZC3HAV1 | 0.702321 | 3 | 0 | 3 |
| BTN2A1 | PDCD2L | 0.699956 | 3 | 0 | 3 |
| BTN2A1 | TOMM40L | 0.692903 | 3 | 0 | 3 |
| BTN2A1 | ZNF140 | 0.686728 | 3 | 0 | 3 |
| BTN2A1 | WDR1 | 0.683031 | 3 | 0 | 3 |
| BTN2A1 | C8orf76 | 0.682967 | 3 | 0 | 3 |
| BTN2A1 | KIF16B | 0.679507 | 3 | 0 | 3 |
| BTN2A1 | NEK4 | 0.678858 | 3 | 0 | 3 |
| BTN2A1 | SRSF6 | 0.675185 | 3 | 0 | 3 |
| BTN2A1 | KCTD7 | 0.674365 | 3 | 0 | 3 |
| BTN2A1 | ZBTB34 | 0.673869 | 4 | 0 | 3 |
For details and further investigation, click here
