| Full name: chromosome 19 open reading frame 18 | Alias Symbol: MGC41906 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 147685 | HGNC ID: HGNC:28642 | Ensembl Gene: ENSG00000177025 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C19orf18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C19orf18 | 147685 | 236847_at | 0.3941 | 0.6112 | |
| GSE26886 | C19orf18 | 147685 | 236847_at | -0.0689 | 0.6249 | |
| GSE45670 | C19orf18 | 147685 | 236847_at | -0.2198 | 0.0950 | |
| GSE53622 | C19orf18 | 147685 | 148347 | -0.4377 | 0.0068 | |
| GSE53624 | C19orf18 | 147685 | 148347 | -0.5456 | 0.0003 | |
| GSE63941 | C19orf18 | 147685 | 236847_at | -1.0009 | 0.0000 | |
| GSE77861 | C19orf18 | 147685 | 236847_at | -0.0693 | 0.5560 | |
| GSE97050 | C19orf18 | 147685 | A_23_P303803 | -0.4578 | 0.1316 | |
| SRP133303 | C19orf18 | 147685 | RNAseq | -0.6989 | 0.0935 | |
| TCGA | C19orf18 | 147685 | RNAseq | -1.1835 | 0.0037 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by C19orf18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C19orf18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C19orf18 | 147685 | 2 | 4 | 24 | |
| GSE20123 | C19orf18 | 147685 | 2 | 3 | 25 | |
| GSE43470 | C19orf18 | 147685 | 3 | 9 | 31 | |
| GSE46452 | C19orf18 | 147685 | 45 | 1 | 13 | |
| GSE47630 | C19orf18 | 147685 | 8 | 6 | 26 | |
| GSE54993 | C19orf18 | 147685 | 18 | 4 | 48 | |
| GSE54994 | C19orf18 | 147685 | 5 | 12 | 36 | |
| GSE60625 | C19orf18 | 147685 | 9 | 0 | 2 | |
| GSE74703 | C19orf18 | 147685 | 3 | 6 | 27 | |
| GSE74704 | C19orf18 | 147685 | 2 | 1 | 17 | |
| TCGA | C19orf18 | 147685 | 20 | 15 | 61 |
Total number of gains: 117; Total number of losses: 61; Total Number of normals: 310.
Somatic mutations of C19orf18:
Generating mutation plots.
Highly correlated genes for C19orf18:
Showing top 20/177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C19orf18 | LRP3 | 0.790377 | 3 | 0 | 3 |
| C19orf18 | ANKRD44 | 0.789473 | 3 | 0 | 3 |
| C19orf18 | ZNF225 | 0.783991 | 3 | 0 | 3 |
| C19orf18 | TMEM181 | 0.780984 | 3 | 0 | 3 |
| C19orf18 | SGCD | 0.769355 | 3 | 0 | 3 |
| C19orf18 | SLC26A11 | 0.767351 | 3 | 0 | 3 |
| C19orf18 | MSRB3 | 0.766458 | 3 | 0 | 3 |
| C19orf18 | ZNF449 | 0.764068 | 3 | 0 | 3 |
| C19orf18 | IKZF4 | 0.7623 | 4 | 0 | 4 |
| C19orf18 | ZNF334 | 0.75937 | 3 | 0 | 3 |
| C19orf18 | ANKRD17 | 0.757826 | 3 | 0 | 3 |
| C19orf18 | TSNARE1 | 0.755498 | 3 | 0 | 3 |
| C19orf18 | TP53I11 | 0.754311 | 3 | 0 | 3 |
| C19orf18 | ZNF358 | 0.749724 | 3 | 0 | 3 |
| C19orf18 | NR2F6 | 0.746478 | 3 | 0 | 3 |
| C19orf18 | KBTBD8 | 0.746297 | 3 | 0 | 3 |
| C19orf18 | RBM6 | 0.742209 | 3 | 0 | 3 |
| C19orf18 | DOK1 | 0.740771 | 3 | 0 | 3 |
| C19orf18 | ARL6IP4 | 0.735746 | 3 | 0 | 3 |
| C19orf18 | SCUBE3 | 0.733567 | 3 | 0 | 3 |
For details and further investigation, click here
