| Full name: kinesin family member 27 | Alias Symbol: DKFZp434D0917 | ||
| Type: protein-coding gene | Cytoband: 9q21.32 | ||
| Entrez ID: 55582 | HGNC ID: HGNC:18632 | Ensembl Gene: ENSG00000165115 | OMIM ID: 611253 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF27 | 55582 | 232514_at | -0.0070 | 0.9879 | |
| GSE26886 | KIF27 | 55582 | 232514_at | 0.0081 | 0.9398 | |
| GSE45670 | KIF27 | 55582 | 232514_at | 0.2719 | 0.1695 | |
| GSE53622 | KIF27 | 55582 | 71658 | -0.3747 | 0.0001 | |
| GSE53624 | KIF27 | 55582 | 71658 | -0.3365 | 0.0000 | |
| GSE63941 | KIF27 | 55582 | 232514_at | 0.2552 | 0.2988 | |
| GSE77861 | KIF27 | 55582 | 232514_at | -0.0175 | 0.8210 | |
| GSE97050 | KIF27 | 55582 | A_24_P109071 | 0.0758 | 0.7685 | |
| SRP007169 | KIF27 | 55582 | RNAseq | -0.5281 | 0.3029 | |
| SRP008496 | KIF27 | 55582 | RNAseq | 0.4421 | 0.2829 | |
| SRP064894 | KIF27 | 55582 | RNAseq | -0.1114 | 0.5665 | |
| SRP133303 | KIF27 | 55582 | RNAseq | -0.3583 | 0.0329 | |
| SRP159526 | KIF27 | 55582 | RNAseq | -0.2042 | 0.6116 | |
| SRP193095 | KIF27 | 55582 | RNAseq | -0.1964 | 0.1186 | |
| SRP219564 | KIF27 | 55582 | RNAseq | -0.2044 | 0.6009 | |
| TCGA | KIF27 | 55582 | RNAseq | -0.1218 | 0.2835 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KIF27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF27 | 55582 | 5 | 10 | 15 | |
| GSE20123 | KIF27 | 55582 | 5 | 10 | 15 | |
| GSE43470 | KIF27 | 55582 | 6 | 3 | 34 | |
| GSE46452 | KIF27 | 55582 | 6 | 14 | 39 | |
| GSE47630 | KIF27 | 55582 | 1 | 18 | 21 | |
| GSE54993 | KIF27 | 55582 | 4 | 2 | 64 | |
| GSE54994 | KIF27 | 55582 | 6 | 12 | 35 | |
| GSE60625 | KIF27 | 55582 | 0 | 0 | 11 | |
| GSE74703 | KIF27 | 55582 | 5 | 3 | 28 | |
| GSE74704 | KIF27 | 55582 | 3 | 7 | 10 | |
| TCGA | KIF27 | 55582 | 20 | 29 | 47 |
Total number of gains: 61; Total number of losses: 108; Total Number of normals: 319.
Somatic mutations of KIF27:
Generating mutation plots.
Highly correlated genes for KIF27:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF27 | ELMOD3 | 0.767942 | 3 | 0 | 3 |
| KIF27 | GPC5 | 0.752359 | 3 | 0 | 3 |
| KIF27 | FOXP4 | 0.715011 | 3 | 0 | 3 |
| KIF27 | HIVEP3 | 0.711884 | 3 | 0 | 3 |
| KIF27 | PIF1 | 0.704393 | 3 | 0 | 3 |
| KIF27 | GNG7 | 0.693766 | 3 | 0 | 3 |
| KIF27 | ZNF470 | 0.693052 | 4 | 0 | 4 |
| KIF27 | NEK8 | 0.691024 | 3 | 0 | 3 |
| KIF27 | NSD1 | 0.681171 | 3 | 0 | 3 |
| KIF27 | ARAF | 0.678618 | 3 | 0 | 3 |
| KIF27 | FAM124A | 0.676833 | 3 | 0 | 3 |
| KIF27 | COL23A1 | 0.668924 | 3 | 0 | 3 |
| KIF27 | ZNF577 | 0.667661 | 3 | 0 | 3 |
| KIF27 | NDUFB4 | 0.663437 | 3 | 0 | 3 |
| KIF27 | LONRF2 | 0.660409 | 3 | 0 | 3 |
| KIF27 | TBC1D22B | 0.65608 | 3 | 0 | 3 |
| KIF27 | PACRGL | 0.653817 | 4 | 0 | 3 |
| KIF27 | TMEM53 | 0.647444 | 4 | 0 | 3 |
| KIF27 | ZNF268 | 0.645537 | 3 | 0 | 3 |
| KIF27 | RNFT2 | 0.644037 | 4 | 0 | 3 |
For details and further investigation, click here
