| Full name: glypican 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q31.3 | ||
| Entrez ID: 2262 | HGNC ID: HGNC:4453 | Ensembl Gene: ENSG00000179399 | OMIM ID: 602446 |
| Drug and gene relationship at DGIdb | |||
Expression of GPC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPC5 | 2262 | 207174_at | 0.0103 | 0.9740 | |
| GSE20347 | GPC5 | 2262 | 207174_at | -0.0342 | 0.4518 | |
| GSE23400 | GPC5 | 2262 | 207174_at | -0.0067 | 0.7882 | |
| GSE26886 | GPC5 | 2262 | 207174_at | 0.0826 | 0.4207 | |
| GSE29001 | GPC5 | 2262 | 207174_at | -0.0940 | 0.5995 | |
| GSE38129 | GPC5 | 2262 | 207174_at | -0.0352 | 0.5904 | |
| GSE45670 | GPC5 | 2262 | 207174_at | 0.1686 | 0.5018 | |
| GSE53622 | GPC5 | 2262 | 87806 | 0.0050 | 0.9848 | |
| GSE53624 | GPC5 | 2262 | 87806 | 0.3047 | 0.0595 | |
| GSE63941 | GPC5 | 2262 | 207174_at | 0.0856 | 0.9044 | |
| GSE77861 | GPC5 | 2262 | 207174_at | -0.0347 | 0.7303 | |
| TCGA | GPC5 | 2262 | RNAseq | 0.1027 | 0.9211 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPC5 | 2262 | 3 | 12 | 15 | |
| GSE20123 | GPC5 | 2262 | 3 | 11 | 16 | |
| GSE43470 | GPC5 | 2262 | 2 | 12 | 29 | |
| GSE46452 | GPC5 | 2262 | 0 | 32 | 27 | |
| GSE47630 | GPC5 | 2262 | 3 | 27 | 10 | |
| GSE54993 | GPC5 | 2262 | 11 | 3 | 56 | |
| GSE54994 | GPC5 | 2262 | 3 | 14 | 36 | |
| GSE60625 | GPC5 | 2262 | 0 | 3 | 8 | |
| GSE74703 | GPC5 | 2262 | 2 | 10 | 24 | |
| GSE74704 | GPC5 | 2262 | 1 | 10 | 9 | |
| TCGA | GPC5 | 2262 | 11 | 37 | 48 |
Total number of gains: 39; Total number of losses: 171; Total Number of normals: 278.
Somatic mutations of GPC5:
Generating mutation plots.
Highly correlated genes for GPC5:
Showing top 20/407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPC5 | KIF27 | 0.752359 | 3 | 0 | 3 |
| GPC5 | CBLN1 | 0.702771 | 4 | 0 | 4 |
| GPC5 | FOXN3-AS2 | 0.702722 | 3 | 0 | 3 |
| GPC5 | MUC19 | 0.700383 | 3 | 0 | 3 |
| GPC5 | NXPE4 | 0.695184 | 3 | 0 | 3 |
| GPC5 | ZKSCAN8 | 0.692559 | 3 | 0 | 3 |
| GPC5 | SLC10A2 | 0.684016 | 3 | 0 | 3 |
| GPC5 | IL17A | 0.683968 | 3 | 0 | 3 |
| GPC5 | ART4 | 0.672652 | 3 | 0 | 3 |
| GPC5 | SULT2A1 | 0.671269 | 5 | 0 | 5 |
| GPC5 | SLC18A1 | 0.665155 | 3 | 0 | 3 |
| GPC5 | FLRT1 | 0.663004 | 3 | 0 | 3 |
| GPC5 | NEUROD1 | 0.662397 | 5 | 0 | 4 |
| GPC5 | SLC13A3 | 0.6568 | 3 | 0 | 3 |
| GPC5 | TBR1 | 0.655938 | 4 | 0 | 3 |
| GPC5 | IL5RA | 0.65291 | 3 | 0 | 3 |
| GPC5 | GPR22 | 0.649022 | 4 | 0 | 4 |
| GPC5 | SLC34A2 | 0.647339 | 3 | 0 | 3 |
| GPC5 | C2orf88 | 0.647277 | 3 | 0 | 3 |
| GPC5 | FGF23 | 0.645991 | 5 | 0 | 4 |
For details and further investigation, click here
