COL23A1

 

Full name: collagen type XXIII alpha 1 chain Alias Symbol: DKFZp434K0621
Type: protein-coding gene Cytoband: 5q35.3
Entrez ID: 91522 HGNC ID: HGNC:22990 Ensembl Gene: ENSG00000050767 OMIM ID: 610043
Drug and gene relationship at DGIdb

 

Expression of COL23A1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 COL23A1 91522 229168_at 0.0168 0.9698
GSE26886 COL23A1 91522 229168_at 0.2991 0.0242
GSE45670 COL23A1 91522 229168_at 0.0519 0.6203
GSE53622 COL23A1 91522 118134 0.0061 0.9628
GSE53624 COL23A1 91522 118134 0.3387 0.0009
GSE63941 COL23A1 91522 229168_at 0.5139 0.1413
GSE77861 COL23A1 91522 229168_at -0.2039 0.0643
GSE97050 COL23A1 91522 A_33_P3341722 0.3764 0.1637
SRP064894 COL23A1 91522 RNAseq 1.2246 0.0002
SRP133303 COL23A1 91522 RNAseq 0.8524 0.1033
SRP219564 COL23A1 91522 RNAseq 1.2472 0.1215
TCGA COL23A1 91522 RNAseq -0.6486 0.0265

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by COL23A1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of COL23A1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 COL23A1 91522 2 13 15
GSE20123 COL23A1 91522 2 13 15
GSE43470 COL23A1 91522 1 11 31
GSE46452 COL23A1 91522 0 27 32
GSE47630 COL23A1 91522 1 20 19
GSE54993 COL23A1 91522 10 2 58
GSE54994 COL23A1 91522 2 17 34
GSE60625 COL23A1 91522 1 0 10
GSE74703 COL23A1 91522 1 7 28
GSE74704 COL23A1 91522 1 6 13
TCGA COL23A1 91522 9 34 53

Total number of gains: 30; Total number of losses: 150; Total Number of normals: 308.  


 

Somatic mutations of COL23A1:

 

Generating mutation plots.

 

Highly correlated genes for COL23A1:

 

Showing top 20/135 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
COL23A1IRF80.801926303
COL23A1ATG130.801558303
COL23A1BTLA0.745774303
COL23A1SIT10.734818303
COL23A1BEGAIN0.729575303
COL23A1DNAJC120.724602303
COL23A1ANGPTL60.716462303
COL23A1TNFSF80.715518303
COL23A1GNGT20.712494403
COL23A1GRIN3B0.700963303
COL23A1DOCK100.697379303
COL23A1RAB370.696289303
COL23A1EBF30.688511303
COL23A1TRHR0.688068303
COL23A1FBXO100.687673303
COL23A1SLC43A20.685878303
COL23A1ARHGEF60.681521303
COL23A1H6PD0.681366303
COL23A1SCML40.678514303
COL23A1COL4A40.674338303

For details and further investigation, click here