| Full name: TBC1 domain family member 22B | Alias Symbol: FLJ20337|dJ744I24.2 | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 55633 | HGNC ID: HGNC:21602 | Ensembl Gene: ENSG00000065491 | OMIM ID: 616880 |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D22B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D22B | 55633 | 223375_at | 0.2392 | 0.6582 | |
| GSE20347 | TBC1D22B | 55633 | 216549_s_at | -0.0311 | 0.5998 | |
| GSE23400 | TBC1D22B | 55633 | 216549_s_at | -0.0786 | 0.0005 | |
| GSE26886 | TBC1D22B | 55633 | 223375_at | -1.5394 | 0.0000 | |
| GSE29001 | TBC1D22B | 55633 | 216549_s_at | -0.0639 | 0.5614 | |
| GSE38129 | TBC1D22B | 55633 | 216549_s_at | -0.0801 | 0.1257 | |
| GSE45670 | TBC1D22B | 55633 | 223375_at | -0.0768 | 0.5851 | |
| GSE53622 | TBC1D22B | 55633 | 107061 | -0.6031 | 0.0000 | |
| GSE53624 | TBC1D22B | 55633 | 39842 | -0.2398 | 0.0123 | |
| GSE63941 | TBC1D22B | 55633 | 223375_at | 0.4888 | 0.0796 | |
| GSE77861 | TBC1D22B | 55633 | 223375_at | -0.3564 | 0.0248 | |
| GSE97050 | TBC1D22B | 55633 | A_23_P58983 | -0.2315 | 0.2733 | |
| SRP007169 | TBC1D22B | 55633 | RNAseq | -0.9599 | 0.0039 | |
| SRP008496 | TBC1D22B | 55633 | RNAseq | -1.1712 | 0.0000 | |
| SRP064894 | TBC1D22B | 55633 | RNAseq | -0.7145 | 0.0000 | |
| SRP133303 | TBC1D22B | 55633 | RNAseq | -0.4852 | 0.0001 | |
| SRP159526 | TBC1D22B | 55633 | RNAseq | -0.4815 | 0.0358 | |
| SRP193095 | TBC1D22B | 55633 | RNAseq | -0.5204 | 0.0000 | |
| SRP219564 | TBC1D22B | 55633 | RNAseq | -0.5282 | 0.0941 | |
| TCGA | TBC1D22B | 55633 | RNAseq | -0.0401 | 0.4620 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TBC1D22B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D22B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D22B | 55633 | 6 | 0 | 24 | |
| GSE20123 | TBC1D22B | 55633 | 6 | 0 | 24 | |
| GSE43470 | TBC1D22B | 55633 | 6 | 1 | 36 | |
| GSE46452 | TBC1D22B | 55633 | 2 | 9 | 48 | |
| GSE47630 | TBC1D22B | 55633 | 8 | 4 | 28 | |
| GSE54993 | TBC1D22B | 55633 | 3 | 1 | 66 | |
| GSE54994 | TBC1D22B | 55633 | 10 | 5 | 38 | |
| GSE60625 | TBC1D22B | 55633 | 1 | 0 | 10 | |
| GSE74703 | TBC1D22B | 55633 | 6 | 0 | 30 | |
| GSE74704 | TBC1D22B | 55633 | 3 | 0 | 17 | |
| TCGA | TBC1D22B | 55633 | 16 | 14 | 66 |
Total number of gains: 67; Total number of losses: 34; Total Number of normals: 387.
Somatic mutations of TBC1D22B:
Generating mutation plots.
Highly correlated genes for TBC1D22B:
Showing top 20/967 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D22B | ALKBH7 | 0.825685 | 3 | 0 | 3 |
| TBC1D22B | KCTD15 | 0.825662 | 3 | 0 | 3 |
| TBC1D22B | GCDH | 0.800413 | 3 | 0 | 3 |
| TBC1D22B | C2orf76 | 0.795166 | 3 | 0 | 3 |
| TBC1D22B | C5orf51 | 0.792705 | 3 | 0 | 3 |
| TBC1D22B | KCTD6 | 0.78802 | 4 | 0 | 4 |
| TBC1D22B | FBXL5 | 0.785581 | 3 | 0 | 3 |
| TBC1D22B | FEM1A | 0.782186 | 3 | 0 | 3 |
| TBC1D22B | CCNYL1 | 0.781251 | 4 | 0 | 4 |
| TBC1D22B | TRAPPC2 | 0.779429 | 3 | 0 | 3 |
| TBC1D22B | ZNF175 | 0.777519 | 3 | 0 | 3 |
| TBC1D22B | DUSP22 | 0.77528 | 5 | 0 | 5 |
| TBC1D22B | S100A16 | 0.774006 | 4 | 0 | 4 |
| TBC1D22B | EGLN1 | 0.760426 | 3 | 0 | 3 |
| TBC1D22B | P2RY13 | 0.756085 | 3 | 0 | 3 |
| TBC1D22B | TMEM120A | 0.755702 | 6 | 0 | 5 |
| TBC1D22B | TMEM234 | 0.753901 | 3 | 0 | 3 |
| TBC1D22B | UTP3 | 0.753567 | 3 | 0 | 3 |
| TBC1D22B | ARID2 | 0.75091 | 3 | 0 | 3 |
| TBC1D22B | CTTNBP2NL | 0.747974 | 5 | 0 | 5 |
For details and further investigation, click here
