| Full name: zinc finger protein 577 | Alias Symbol: MGC4400 | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 84765 | HGNC ID: HGNC:28673 | Ensembl Gene: ENSG00000161551 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF577:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF577 | 84765 | 223581_at | 0.3552 | 0.2818 | |
| GSE26886 | ZNF577 | 84765 | 223581_at | -0.1765 | 0.0948 | |
| GSE45670 | ZNF577 | 84765 | 223581_at | -0.0043 | 0.9858 | |
| GSE53622 | ZNF577 | 84765 | 72215 | -0.2877 | 0.0030 | |
| GSE53624 | ZNF577 | 84765 | 72215 | -0.2732 | 0.0001 | |
| GSE63941 | ZNF577 | 84765 | 223581_at | 0.2439 | 0.5182 | |
| GSE77861 | ZNF577 | 84765 | 1556905_at | -0.0229 | 0.8578 | |
| GSE97050 | ZNF577 | 84765 | A_23_P309207 | -0.4443 | 0.1606 | |
| SRP007169 | ZNF577 | 84765 | RNAseq | -0.0401 | 0.9398 | |
| SRP064894 | ZNF577 | 84765 | RNAseq | -0.3071 | 0.2118 | |
| SRP133303 | ZNF577 | 84765 | RNAseq | -0.2452 | 0.1373 | |
| SRP159526 | ZNF577 | 84765 | RNAseq | -0.8506 | 0.0167 | |
| SRP193095 | ZNF577 | 84765 | RNAseq | 0.0574 | 0.6888 | |
| SRP219564 | ZNF577 | 84765 | RNAseq | -0.6691 | 0.2113 | |
| TCGA | ZNF577 | 84765 | RNAseq | -0.5593 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF577 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF577:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF577 | 84765 | 3 | 4 | 23 | |
| GSE20123 | ZNF577 | 84765 | 3 | 3 | 24 | |
| GSE43470 | ZNF577 | 84765 | 2 | 12 | 29 | |
| GSE46452 | ZNF577 | 84765 | 45 | 1 | 13 | |
| GSE47630 | ZNF577 | 84765 | 10 | 6 | 24 | |
| GSE54993 | ZNF577 | 84765 | 17 | 4 | 49 | |
| GSE54994 | ZNF577 | 84765 | 4 | 14 | 35 | |
| GSE60625 | ZNF577 | 84765 | 9 | 0 | 2 | |
| GSE74703 | ZNF577 | 84765 | 2 | 8 | 26 | |
| GSE74704 | ZNF577 | 84765 | 3 | 1 | 16 | |
| TCGA | ZNF577 | 84765 | 14 | 20 | 62 |
Total number of gains: 112; Total number of losses: 73; Total Number of normals: 303.
Somatic mutations of ZNF577:
Generating mutation plots.
Highly correlated genes for ZNF577:
Showing top 20/53 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF577 | KLHL28 | 0.768417 | 3 | 0 | 3 |
| ZNF577 | CRCP | 0.759684 | 3 | 0 | 3 |
| ZNF577 | CIAO1 | 0.737649 | 3 | 0 | 3 |
| ZNF577 | SLC35E1 | 0.730183 | 3 | 0 | 3 |
| ZNF577 | ZNF567 | 0.713904 | 3 | 0 | 3 |
| ZNF577 | TAF15 | 0.705924 | 3 | 0 | 3 |
| ZNF577 | RPL7L1 | 0.696201 | 3 | 0 | 3 |
| ZNF577 | RAB12 | 0.694097 | 3 | 0 | 3 |
| ZNF577 | FAM90A1 | 0.68662 | 3 | 0 | 3 |
| ZNF577 | LRRFIP1 | 0.683835 | 3 | 0 | 3 |
| ZNF577 | HMBOX1 | 0.672017 | 3 | 0 | 3 |
| ZNF577 | KIF27 | 0.667661 | 3 | 0 | 3 |
| ZNF577 | POU2F1 | 0.654984 | 4 | 0 | 3 |
| ZNF577 | IRAK1BP1 | 0.636579 | 3 | 0 | 3 |
| ZNF577 | ZNF345 | 0.635432 | 4 | 0 | 3 |
| ZNF577 | SYAP1 | 0.631383 | 4 | 0 | 3 |
| ZNF577 | DUSP8 | 0.630537 | 3 | 0 | 3 |
| ZNF577 | ZKSCAN1 | 0.626224 | 3 | 0 | 3 |
| ZNF577 | CLK2 | 0.622483 | 3 | 0 | 3 |
| ZNF577 | CHD8 | 0.619429 | 4 | 0 | 3 |
For details and further investigation, click here
