| Full name: NADH:ubiquinone oxidoreductase subunit B4 | Alias Symbol: B15 | ||
| Type: protein-coding gene | Cytoband: 3q13.33 | ||
| Entrez ID: 4710 | HGNC ID: HGNC:7699 | Ensembl Gene: ENSG00000065518 | OMIM ID: 603840 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFB4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFB4 | 4710 | 218226_s_at | 0.1542 | 0.4410 | |
| GSE20347 | NDUFB4 | 4710 | 218226_s_at | 0.1879 | 0.0736 | |
| GSE23400 | NDUFB4 | 4710 | 218226_s_at | 0.2323 | 0.0060 | |
| GSE26886 | NDUFB4 | 4710 | 218226_s_at | 0.6984 | 0.0001 | |
| GSE29001 | NDUFB4 | 4710 | 218226_s_at | -0.1756 | 0.7224 | |
| GSE38129 | NDUFB4 | 4710 | 218226_s_at | 0.1744 | 0.0891 | |
| GSE45670 | NDUFB4 | 4710 | 218226_s_at | 0.1883 | 0.0918 | |
| GSE53622 | NDUFB4 | 4710 | 7186 | -0.2301 | 0.0001 | |
| GSE53624 | NDUFB4 | 4710 | 7186 | 0.2366 | 0.0000 | |
| GSE63941 | NDUFB4 | 4710 | 218226_s_at | 0.3731 | 0.0968 | |
| GSE77861 | NDUFB4 | 4710 | 218226_s_at | -0.1484 | 0.7131 | |
| GSE97050 | NDUFB4 | 4710 | A_23_P69468 | -0.0153 | 0.9706 | |
| SRP007169 | NDUFB4 | 4710 | RNAseq | -0.4256 | 0.3259 | |
| SRP008496 | NDUFB4 | 4710 | RNAseq | -0.4571 | 0.0595 | |
| SRP064894 | NDUFB4 | 4710 | RNAseq | 0.1941 | 0.5087 | |
| SRP133303 | NDUFB4 | 4710 | RNAseq | 0.2796 | 0.2295 | |
| SRP159526 | NDUFB4 | 4710 | RNAseq | -0.0037 | 0.9881 | |
| SRP193095 | NDUFB4 | 4710 | RNAseq | -0.1268 | 0.4424 | |
| SRP219564 | NDUFB4 | 4710 | RNAseq | -0.2949 | 0.1375 | |
| TCGA | NDUFB4 | 4710 | RNAseq | 0.0961 | 0.0625 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFB4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFB4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFB4 | 4710 | 18 | 0 | 12 | |
| GSE20123 | NDUFB4 | 4710 | 18 | 0 | 12 | |
| GSE43470 | NDUFB4 | 4710 | 21 | 1 | 21 | |
| GSE46452 | NDUFB4 | 4710 | 14 | 5 | 40 | |
| GSE47630 | NDUFB4 | 4710 | 16 | 5 | 19 | |
| GSE54993 | NDUFB4 | 4710 | 2 | 6 | 62 | |
| GSE54994 | NDUFB4 | 4710 | 30 | 4 | 19 | |
| GSE60625 | NDUFB4 | 4710 | 0 | 6 | 5 | |
| GSE74703 | NDUFB4 | 4710 | 17 | 1 | 18 | |
| GSE74704 | NDUFB4 | 4710 | 13 | 0 | 7 | |
| TCGA | NDUFB4 | 4710 | 53 | 7 | 36 |
Total number of gains: 202; Total number of losses: 35; Total Number of normals: 251.
Somatic mutations of NDUFB4:
Generating mutation plots.
Highly correlated genes for NDUFB4:
Showing top 20/461 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFB4 | ZNF558 | 0.777033 | 3 | 0 | 3 |
| NDUFB4 | SSBP4 | 0.773176 | 3 | 0 | 3 |
| NDUFB4 | RPS27 | 0.766143 | 4 | 0 | 4 |
| NDUFB4 | NACC1 | 0.763559 | 3 | 0 | 3 |
| NDUFB4 | RIOK1 | 0.75539 | 3 | 0 | 3 |
| NDUFB4 | DHX37 | 0.749003 | 3 | 0 | 3 |
| NDUFB4 | HCFC1R1 | 0.748828 | 3 | 0 | 3 |
| NDUFB4 | B3GALT6 | 0.74527 | 3 | 0 | 3 |
| NDUFB4 | BRD4 | 0.745228 | 3 | 0 | 3 |
| NDUFB4 | RBM38 | 0.733166 | 3 | 0 | 3 |
| NDUFB4 | LZTS2 | 0.730961 | 3 | 0 | 3 |
| NDUFB4 | GRWD1 | 0.727134 | 3 | 0 | 3 |
| NDUFB4 | AGTRAP | 0.725711 | 3 | 0 | 3 |
| NDUFB4 | XAB2 | 0.720223 | 3 | 0 | 3 |
| NDUFB4 | POLRMT | 0.717728 | 3 | 0 | 3 |
| NDUFB4 | NAP1L4 | 0.717631 | 3 | 0 | 3 |
| NDUFB4 | ARID1A | 0.713157 | 4 | 0 | 4 |
| NDUFB4 | RPL19 | 0.71087 | 4 | 0 | 3 |
| NDUFB4 | RPTOR | 0.707956 | 3 | 0 | 3 |
| NDUFB4 | CLASRP | 0.707094 | 3 | 0 | 3 |
For details and further investigation, click here
