| Full name: kinesin associated protein 3 | Alias Symbol: SMAP|KAP3|FLA3|KAP-1 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 22920 | HGNC ID: HGNC:17060 | Ensembl Gene: ENSG00000075945 | OMIM ID: 601836 |
| Drug and gene relationship at DGIdb | |||
Expression of KIFAP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIFAP3 | 22920 | 203333_at | 0.1597 | 0.7382 | |
| GSE20347 | KIFAP3 | 22920 | 203333_at | 0.0722 | 0.7646 | |
| GSE23400 | KIFAP3 | 22920 | 203333_at | 0.2565 | 0.0010 | |
| GSE26886 | KIFAP3 | 22920 | 203333_at | -0.6136 | 0.0161 | |
| GSE29001 | KIFAP3 | 22920 | 203333_at | 0.1524 | 0.7379 | |
| GSE38129 | KIFAP3 | 22920 | 203333_at | 0.1701 | 0.3780 | |
| GSE45670 | KIFAP3 | 22920 | 203333_at | -0.0303 | 0.9033 | |
| GSE53622 | KIFAP3 | 22920 | 75678 | 0.4547 | 0.0000 | |
| GSE53624 | KIFAP3 | 22920 | 75678 | 0.4803 | 0.0000 | |
| GSE63941 | KIFAP3 | 22920 | 203333_at | -0.8344 | 0.2280 | |
| GSE77861 | KIFAP3 | 22920 | 203333_at | 0.1478 | 0.7936 | |
| GSE97050 | KIFAP3 | 22920 | A_23_P62920 | -0.0011 | 0.9979 | |
| SRP007169 | KIFAP3 | 22920 | RNAseq | 0.0061 | 0.9895 | |
| SRP008496 | KIFAP3 | 22920 | RNAseq | 0.8689 | 0.0331 | |
| SRP064894 | KIFAP3 | 22920 | RNAseq | 0.4075 | 0.0014 | |
| SRP133303 | KIFAP3 | 22920 | RNAseq | 0.5792 | 0.0069 | |
| SRP159526 | KIFAP3 | 22920 | RNAseq | 0.4969 | 0.0049 | |
| SRP193095 | KIFAP3 | 22920 | RNAseq | 0.3040 | 0.0191 | |
| SRP219564 | KIFAP3 | 22920 | RNAseq | 0.2922 | 0.4264 | |
| TCGA | KIFAP3 | 22920 | RNAseq | 0.1426 | 0.0104 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KIFAP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIFAP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIFAP3 | 22920 | 12 | 1 | 17 | |
| GSE20123 | KIFAP3 | 22920 | 12 | 1 | 17 | |
| GSE43470 | KIFAP3 | 22920 | 7 | 2 | 34 | |
| GSE46452 | KIFAP3 | 22920 | 3 | 1 | 55 | |
| GSE47630 | KIFAP3 | 22920 | 14 | 0 | 26 | |
| GSE54993 | KIFAP3 | 22920 | 0 | 6 | 64 | |
| GSE54994 | KIFAP3 | 22920 | 16 | 0 | 37 | |
| GSE60625 | KIFAP3 | 22920 | 0 | 0 | 11 | |
| GSE74703 | KIFAP3 | 22920 | 7 | 2 | 27 | |
| GSE74704 | KIFAP3 | 22920 | 6 | 0 | 14 | |
| TCGA | KIFAP3 | 22920 | 43 | 3 | 50 |
Total number of gains: 120; Total number of losses: 16; Total Number of normals: 352.
Somatic mutations of KIFAP3:
Generating mutation plots.
Highly correlated genes for KIFAP3:
Showing top 20/95 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIFAP3 | CXorf40A | 0.653633 | 5 | 0 | 5 |
| KIFAP3 | FASTKD5 | 0.632388 | 5 | 0 | 4 |
| KIFAP3 | XRN2 | 0.63145 | 3 | 0 | 3 |
| KIFAP3 | ATP6V0D1 | 0.62731 | 6 | 0 | 4 |
| KIFAP3 | TMEM187 | 0.624056 | 4 | 0 | 4 |
| KIFAP3 | AP4M1 | 0.61893 | 3 | 0 | 3 |
| KIFAP3 | VANGL2 | 0.613972 | 3 | 0 | 3 |
| KIFAP3 | ACBD3 | 0.613672 | 4 | 0 | 3 |
| KIFAP3 | SDHC | 0.604981 | 3 | 0 | 3 |
| KIFAP3 | VPS41 | 0.604027 | 7 | 0 | 6 |
| KIFAP3 | TRAPPC2L | 0.598031 | 4 | 0 | 3 |
| KIFAP3 | ECI2 | 0.595789 | 7 | 0 | 6 |
| KIFAP3 | NME7 | 0.59506 | 8 | 0 | 5 |
| KIFAP3 | RPRD1B | 0.59154 | 3 | 0 | 3 |
| KIFAP3 | ZNF607 | 0.590283 | 4 | 0 | 3 |
| KIFAP3 | PPIP5K2 | 0.58402 | 6 | 0 | 4 |
| KIFAP3 | KCTD10 | 0.581728 | 3 | 0 | 3 |
| KIFAP3 | SAMM50 | 0.580636 | 6 | 0 | 4 |
| KIFAP3 | SDF2 | 0.580049 | 4 | 0 | 3 |
| KIFAP3 | CXorf40B | 0.578565 | 5 | 0 | 4 |
For details and further investigation, click here
