| Full name: regulation of nuclear pre-mRNA domain containing 1B | Alias Symbol: dJ1057B20.2|DKFZp434P0735|CREPT|FLJ44520|NET60|Kub5-Hera|K-H | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 58490 | HGNC ID: HGNC:16209 | Ensembl Gene: ENSG00000101413 | OMIM ID: 614694 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPRD1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPRD1B | 58490 | 225024_at | 0.7027 | 0.0983 | |
| GSE26886 | RPRD1B | 58490 | 225024_at | -0.3131 | 0.0665 | |
| GSE45670 | RPRD1B | 58490 | 225024_at | 0.1806 | 0.2189 | |
| GSE53622 | RPRD1B | 58490 | 75860 | 0.3607 | 0.0000 | |
| GSE53624 | RPRD1B | 58490 | 75860 | 0.1746 | 0.0017 | |
| GSE63941 | RPRD1B | 58490 | 225024_at | 0.7435 | 0.0756 | |
| GSE77861 | RPRD1B | 58490 | 225024_at | 0.1999 | 0.1751 | |
| GSE97050 | RPRD1B | 58490 | A_24_P250499 | 0.8130 | 0.2237 | |
| SRP007169 | RPRD1B | 58490 | RNAseq | 0.2281 | 0.5158 | |
| SRP008496 | RPRD1B | 58490 | RNAseq | 0.4300 | 0.0426 | |
| SRP064894 | RPRD1B | 58490 | RNAseq | 0.3374 | 0.0539 | |
| SRP133303 | RPRD1B | 58490 | RNAseq | 0.3780 | 0.0009 | |
| SRP159526 | RPRD1B | 58490 | RNAseq | 0.3040 | 0.1082 | |
| SRP193095 | RPRD1B | 58490 | RNAseq | 0.2300 | 0.0024 | |
| SRP219564 | RPRD1B | 58490 | RNAseq | 0.3310 | 0.1491 | |
| TCGA | RPRD1B | 58490 | RNAseq | 0.0275 | 0.5579 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPRD1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPRD1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPRD1B | 58490 | 14 | 2 | 14 | |
| GSE20123 | RPRD1B | 58490 | 14 | 2 | 14 | |
| GSE43470 | RPRD1B | 58490 | 12 | 0 | 31 | |
| GSE46452 | RPRD1B | 58490 | 29 | 0 | 30 | |
| GSE47630 | RPRD1B | 58490 | 24 | 0 | 16 | |
| GSE54993 | RPRD1B | 58490 | 0 | 17 | 53 | |
| GSE54994 | RPRD1B | 58490 | 23 | 0 | 30 | |
| GSE60625 | RPRD1B | 58490 | 0 | 0 | 11 | |
| GSE74703 | RPRD1B | 58490 | 10 | 0 | 26 | |
| GSE74704 | RPRD1B | 58490 | 10 | 1 | 9 | |
| TCGA | RPRD1B | 58490 | 47 | 4 | 45 |
Total number of gains: 183; Total number of losses: 26; Total Number of normals: 279.
Somatic mutations of RPRD1B:
Generating mutation plots.
Highly correlated genes for RPRD1B:
Showing top 20/454 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPRD1B | TM2D2 | 0.813572 | 3 | 0 | 3 |
| RPRD1B | TTC4 | 0.810412 | 3 | 0 | 3 |
| RPRD1B | AAR2 | 0.800582 | 3 | 0 | 3 |
| RPRD1B | TBK1 | 0.763155 | 3 | 0 | 3 |
| RPRD1B | NSL1 | 0.751255 | 3 | 0 | 3 |
| RPRD1B | RAD21 | 0.742752 | 3 | 0 | 3 |
| RPRD1B | UHMK1 | 0.739524 | 3 | 0 | 3 |
| RPRD1B | PARL | 0.732486 | 3 | 0 | 3 |
| RPRD1B | LSM2 | 0.731362 | 3 | 0 | 3 |
| RPRD1B | FXR1 | 0.726755 | 3 | 0 | 3 |
| RPRD1B | XPO7 | 0.726346 | 4 | 0 | 4 |
| RPRD1B | EARS2 | 0.724892 | 3 | 0 | 3 |
| RPRD1B | RNF34 | 0.718634 | 4 | 0 | 3 |
| RPRD1B | TRIM59 | 0.713394 | 3 | 0 | 3 |
| RPRD1B | KIF15 | 0.708399 | 3 | 0 | 3 |
| RPRD1B | ALG10 | 0.705994 | 3 | 0 | 3 |
| RPRD1B | PLEKHB2 | 0.704192 | 4 | 0 | 4 |
| RPRD1B | DDOST | 0.703067 | 3 | 0 | 3 |
| RPRD1B | SNX30 | 0.702206 | 4 | 0 | 4 |
| RPRD1B | MIS18A | 0.699194 | 3 | 0 | 3 |
For details and further investigation, click here
