| Full name: FAST kinase domains 5 | Alias Symbol: FLJ13149 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 60493 | HGNC ID: HGNC:25790 | Ensembl Gene: ENSG00000215251 | OMIM ID: 614272 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FASTKD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FASTKD5 | 60493 | 219016_at | 0.1846 | 0.7172 | |
| GSE20347 | FASTKD5 | 60493 | 219016_at | 0.3029 | 0.0105 | |
| GSE23400 | FASTKD5 | 60493 | 219016_at | 0.1436 | 0.0039 | |
| GSE26886 | FASTKD5 | 60493 | 219016_at | -0.7958 | 0.0440 | |
| GSE29001 | FASTKD5 | 60493 | 219016_at | 0.2176 | 0.2468 | |
| GSE38129 | FASTKD5 | 60493 | 219016_at | 0.3682 | 0.0022 | |
| GSE45670 | FASTKD5 | 60493 | 219016_at | 0.3159 | 0.1043 | |
| GSE53622 | FASTKD5 | 60493 | 36936 | 0.1100 | 0.1312 | |
| GSE53624 | FASTKD5 | 60493 | 36936 | 0.1462 | 0.0671 | |
| GSE63941 | FASTKD5 | 60493 | 219016_at | 0.0357 | 0.9371 | |
| GSE77861 | FASTKD5 | 60493 | 219016_at | 0.3885 | 0.1346 | |
| GSE97050 | FASTKD5 | 60493 | A_23_P380724 | 0.0426 | 0.8853 | |
| SRP007169 | FASTKD5 | 60493 | RNAseq | -0.0193 | 0.9602 | |
| SRP008496 | FASTKD5 | 60493 | RNAseq | 0.3783 | 0.1256 | |
| SRP064894 | FASTKD5 | 60493 | RNAseq | -0.2017 | 0.3716 | |
| SRP133303 | FASTKD5 | 60493 | RNAseq | 0.1619 | 0.1289 | |
| SRP159526 | FASTKD5 | 60493 | RNAseq | 0.3154 | 0.2480 | |
| SRP193095 | FASTKD5 | 60493 | RNAseq | -0.0203 | 0.8433 | |
| SRP219564 | FASTKD5 | 60493 | RNAseq | 0.1656 | 0.6618 | |
| TCGA | FASTKD5 | 60493 | RNAseq | 0.0179 | 0.7519 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FASTKD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FASTKD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FASTKD5 | 60493 | 12 | 3 | 15 | |
| GSE20123 | FASTKD5 | 60493 | 13 | 3 | 14 | |
| GSE43470 | FASTKD5 | 60493 | 10 | 1 | 32 | |
| GSE46452 | FASTKD5 | 60493 | 26 | 1 | 32 | |
| GSE47630 | FASTKD5 | 60493 | 18 | 4 | 18 | |
| GSE54993 | FASTKD5 | 60493 | 2 | 14 | 54 | |
| GSE54994 | FASTKD5 | 60493 | 24 | 2 | 27 | |
| GSE60625 | FASTKD5 | 60493 | 0 | 0 | 11 | |
| GSE74703 | FASTKD5 | 60493 | 9 | 1 | 26 | |
| GSE74704 | FASTKD5 | 60493 | 8 | 1 | 11 | |
| TCGA | FASTKD5 | 60493 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of FASTKD5:
Generating mutation plots.
Highly correlated genes for FASTKD5:
Showing top 20/322 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FASTKD5 | SNAPIN | 0.786823 | 3 | 0 | 3 |
| FASTKD5 | NIT1 | 0.752318 | 3 | 0 | 3 |
| FASTKD5 | PSMC3 | 0.742688 | 3 | 0 | 3 |
| FASTKD5 | GPBP1 | 0.722305 | 3 | 0 | 3 |
| FASTKD5 | ATP6V1B2 | 0.717659 | 3 | 0 | 3 |
| FASTKD5 | HSDL1 | 0.713016 | 3 | 0 | 3 |
| FASTKD5 | KDSR | 0.707263 | 3 | 0 | 3 |
| FASTKD5 | ANKRD13C | 0.703287 | 3 | 0 | 3 |
| FASTKD5 | CSNK1G3 | 0.690974 | 3 | 0 | 3 |
| FASTKD5 | NUDCD2 | 0.688117 | 3 | 0 | 3 |
| FASTKD5 | PAK1 | 0.685501 | 4 | 0 | 4 |
| FASTKD5 | KIF3A | 0.684968 | 3 | 0 | 3 |
| FASTKD5 | ATP9A | 0.680371 | 3 | 0 | 3 |
| FASTKD5 | CMC1 | 0.680331 | 3 | 0 | 3 |
| FASTKD5 | LGALSL | 0.677036 | 3 | 0 | 3 |
| FASTKD5 | TRMT6 | 0.676991 | 7 | 0 | 7 |
| FASTKD5 | PITPNA | 0.674676 | 3 | 0 | 3 |
| FASTKD5 | TADA1 | 0.674442 | 3 | 0 | 3 |
| FASTKD5 | FYTTD1 | 0.672457 | 3 | 0 | 3 |
| FASTKD5 | MED17 | 0.666145 | 4 | 0 | 3 |
For details and further investigation, click here
