| Full name: adaptor related protein complex 4 subunit mu 1 | Alias Symbol: MU-ARP2|MU-4|SPG50 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 9179 | HGNC ID: HGNC:574 | Ensembl Gene: ENSG00000221838 | OMIM ID: 602296 |
| Drug and gene relationship at DGIdb | |||
Expression of AP4M1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AP4M1 | 9179 | 209837_at | 0.1568 | 0.8107 | |
| GSE20347 | AP4M1 | 9179 | 209837_at | 0.0934 | 0.5493 | |
| GSE23400 | AP4M1 | 9179 | 209837_at | -0.0831 | 0.1975 | |
| GSE26886 | AP4M1 | 9179 | 209837_at | 0.0583 | 0.8263 | |
| GSE29001 | AP4M1 | 9179 | 209837_at | -0.1250 | 0.4876 | |
| GSE38129 | AP4M1 | 9179 | 209837_at | 0.1419 | 0.2016 | |
| GSE45670 | AP4M1 | 9179 | 209837_at | 0.0180 | 0.9081 | |
| GSE53622 | AP4M1 | 9179 | 81122 | 0.3909 | 0.0000 | |
| GSE53624 | AP4M1 | 9179 | 81122 | 0.1860 | 0.0313 | |
| GSE63941 | AP4M1 | 9179 | 209837_at | 0.0566 | 0.8933 | |
| GSE77861 | AP4M1 | 9179 | 209837_at | -0.0170 | 0.9122 | |
| GSE97050 | AP4M1 | 9179 | A_23_P157051 | 0.0906 | 0.8114 | |
| SRP007169 | AP4M1 | 9179 | RNAseq | -1.0714 | 0.0040 | |
| SRP008496 | AP4M1 | 9179 | RNAseq | -0.6047 | 0.1091 | |
| SRP064894 | AP4M1 | 9179 | RNAseq | 0.5908 | 0.0141 | |
| SRP133303 | AP4M1 | 9179 | RNAseq | 0.4640 | 0.0654 | |
| SRP159526 | AP4M1 | 9179 | RNAseq | 0.1598 | 0.6587 | |
| SRP193095 | AP4M1 | 9179 | RNAseq | 0.3764 | 0.0105 | |
| SRP219564 | AP4M1 | 9179 | RNAseq | 0.0376 | 0.9191 | |
| TCGA | AP4M1 | 9179 | RNAseq | 0.0636 | 0.3346 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AP4M1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AP4M1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AP4M1 | 9179 | 13 | 0 | 17 | |
| GSE20123 | AP4M1 | 9179 | 13 | 0 | 17 | |
| GSE43470 | AP4M1 | 9179 | 6 | 2 | 35 | |
| GSE46452 | AP4M1 | 9179 | 11 | 1 | 47 | |
| GSE47630 | AP4M1 | 9179 | 7 | 3 | 30 | |
| GSE54993 | AP4M1 | 9179 | 1 | 9 | 60 | |
| GSE54994 | AP4M1 | 9179 | 15 | 3 | 35 | |
| GSE60625 | AP4M1 | 9179 | 0 | 0 | 11 | |
| GSE74703 | AP4M1 | 9179 | 6 | 1 | 29 | |
| GSE74704 | AP4M1 | 9179 | 9 | 0 | 11 | |
| TCGA | AP4M1 | 9179 | 52 | 6 | 38 |
Total number of gains: 133; Total number of losses: 25; Total Number of normals: 330.
Somatic mutations of AP4M1:
Generating mutation plots.
Highly correlated genes for AP4M1:
Showing top 20/209 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AP4M1 | STUB1 | 0.735198 | 3 | 0 | 3 |
| AP4M1 | MRPL38 | 0.716228 | 3 | 0 | 3 |
| AP4M1 | CRIP1 | 0.711509 | 3 | 0 | 3 |
| AP4M1 | PTPRU | 0.710171 | 3 | 0 | 3 |
| AP4M1 | ANKIB1 | 0.705763 | 3 | 0 | 3 |
| AP4M1 | TSR2 | 0.6828 | 3 | 0 | 3 |
| AP4M1 | OS9 | 0.677864 | 3 | 0 | 3 |
| AP4M1 | ARHGAP42 | 0.677225 | 3 | 0 | 3 |
| AP4M1 | LSM10 | 0.669547 | 3 | 0 | 3 |
| AP4M1 | NRGN | 0.669071 | 3 | 0 | 3 |
| AP4M1 | B9D2 | 0.668069 | 3 | 0 | 3 |
| AP4M1 | CTDSP1 | 0.666518 | 3 | 0 | 3 |
| AP4M1 | AP2A2 | 0.666152 | 3 | 0 | 3 |
| AP4M1 | LRP6 | 0.658483 | 3 | 0 | 3 |
| AP4M1 | FBXW9 | 0.657265 | 3 | 0 | 3 |
| AP4M1 | AKT1 | 0.65409 | 4 | 0 | 4 |
| AP4M1 | DOCK7 | 0.646863 | 3 | 0 | 3 |
| AP4M1 | SND1 | 0.640822 | 3 | 0 | 3 |
| AP4M1 | ZNF578 | 0.638163 | 3 | 0 | 3 |
| AP4M1 | ATG4C | 0.637416 | 3 | 0 | 3 |
For details and further investigation, click here
