| Full name: stromal cell derived factor 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 6388 | HGNC ID: HGNC:10675 | Ensembl Gene: ENSG00000132581 | OMIM ID: 602934 |
| Drug and gene relationship at DGIdb | |||
Expression of SDF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDF2 | 6388 | 203090_at | 0.0050 | 0.9896 | |
| GSE20347 | SDF2 | 6388 | 203090_at | 0.1413 | 0.1792 | |
| GSE23400 | SDF2 | 6388 | 203090_at | 0.0685 | 0.1033 | |
| GSE26886 | SDF2 | 6388 | 203090_at | 0.3644 | 0.0536 | |
| GSE29001 | SDF2 | 6388 | 203090_at | 0.1489 | 0.4658 | |
| GSE38129 | SDF2 | 6388 | 203090_at | 0.2429 | 0.0537 | |
| GSE45670 | SDF2 | 6388 | 203090_at | 0.2754 | 0.0277 | |
| GSE53622 | SDF2 | 6388 | 1327 | 0.2718 | 0.0000 | |
| GSE53624 | SDF2 | 6388 | 1327 | 0.3039 | 0.0000 | |
| GSE63941 | SDF2 | 6388 | 203090_at | -1.1366 | 0.0155 | |
| GSE77861 | SDF2 | 6388 | 203090_at | 0.4213 | 0.0899 | |
| GSE97050 | SDF2 | 6388 | A_23_P107313 | 0.2178 | 0.3701 | |
| SRP007169 | SDF2 | 6388 | RNAseq | -0.6162 | 0.1212 | |
| SRP008496 | SDF2 | 6388 | RNAseq | -0.4242 | 0.0548 | |
| SRP064894 | SDF2 | 6388 | RNAseq | 0.3061 | 0.2317 | |
| SRP133303 | SDF2 | 6388 | RNAseq | 0.2228 | 0.1259 | |
| SRP159526 | SDF2 | 6388 | RNAseq | 0.2079 | 0.2783 | |
| SRP193095 | SDF2 | 6388 | RNAseq | -0.0382 | 0.7719 | |
| SRP219564 | SDF2 | 6388 | RNAseq | -0.1261 | 0.6801 | |
| TCGA | SDF2 | 6388 | RNAseq | 0.0248 | 0.6373 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SDF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDF2 | 6388 | 9 | 1 | 20 | |
| GSE20123 | SDF2 | 6388 | 9 | 1 | 20 | |
| GSE43470 | SDF2 | 6388 | 0 | 1 | 42 | |
| GSE46452 | SDF2 | 6388 | 33 | 1 | 25 | |
| GSE47630 | SDF2 | 6388 | 7 | 1 | 32 | |
| GSE54993 | SDF2 | 6388 | 2 | 3 | 65 | |
| GSE54994 | SDF2 | 6388 | 7 | 6 | 40 | |
| GSE60625 | SDF2 | 6388 | 4 | 0 | 7 | |
| GSE74703 | SDF2 | 6388 | 0 | 1 | 35 | |
| GSE74704 | SDF2 | 6388 | 7 | 1 | 12 | |
| TCGA | SDF2 | 6388 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of SDF2:
Generating mutation plots.
Highly correlated genes for SDF2:
Showing top 20/210 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDF2 | SMG8 | 0.671866 | 5 | 0 | 5 |
| SDF2 | RANBP1 | 0.649606 | 8 | 0 | 8 |
| SDF2 | FKBP10 | 0.644045 | 4 | 0 | 3 |
| SDF2 | CCDC77 | 0.639446 | 5 | 0 | 4 |
| SDF2 | PSEN2 | 0.627714 | 3 | 0 | 3 |
| SDF2 | MRPL51 | 0.615599 | 5 | 0 | 5 |
| SDF2 | DNAJB11 | 0.614708 | 5 | 0 | 5 |
| SDF2 | PRDX3 | 0.60893 | 5 | 0 | 4 |
| SDF2 | NLK | 0.607352 | 8 | 0 | 6 |
| SDF2 | LSM8 | 0.605145 | 6 | 0 | 5 |
| SDF2 | CAPRIN2 | 0.59629 | 3 | 0 | 3 |
| SDF2 | FOXM1 | 0.594665 | 7 | 0 | 6 |
| SDF2 | LAMTOR5 | 0.591214 | 3 | 0 | 3 |
| SDF2 | MOGS | 0.590267 | 7 | 0 | 6 |
| SDF2 | RCN2 | 0.588248 | 9 | 0 | 7 |
| SDF2 | RRAGB | 0.587129 | 5 | 0 | 3 |
| SDF2 | PDIA4 | 0.585509 | 7 | 0 | 6 |
| SDF2 | KIFAP3 | 0.580049 | 4 | 0 | 3 |
| SDF2 | KIAA0100 | 0.579571 | 8 | 0 | 5 |
| SDF2 | PSMD14 | 0.576307 | 6 | 0 | 5 |
For details and further investigation, click here
