| Full name: enoyl-CoA delta isomerase 2 | Alias Symbol: ACBD2|DRS1|HCA88 | ||
| Type: protein-coding gene | Cytoband: 6p25.2 | ||
| Entrez ID: 10455 | HGNC ID: HGNC:14601 | Ensembl Gene: ENSG00000198721 | OMIM ID: 608024 |
| Drug and gene relationship at DGIdb | |||
Expression of ECI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECI2 | 10455 | 218025_s_at | 0.2642 | 0.5465 | |
| GSE20347 | ECI2 | 10455 | 218025_s_at | -0.2783 | 0.3447 | |
| GSE23400 | ECI2 | 10455 | 218025_s_at | 0.0588 | 0.5484 | |
| GSE26886 | ECI2 | 10455 | 218025_s_at | -0.7568 | 0.0119 | |
| GSE29001 | ECI2 | 10455 | 218025_s_at | -0.0370 | 0.9425 | |
| GSE38129 | ECI2 | 10455 | 218025_s_at | -0.4025 | 0.0832 | |
| GSE45670 | ECI2 | 10455 | 218025_s_at | -0.4536 | 0.0594 | |
| GSE53622 | ECI2 | 10455 | 5987 | -0.1695 | 0.0727 | |
| GSE53624 | ECI2 | 10455 | 5987 | -0.0725 | 0.4405 | |
| GSE63941 | ECI2 | 10455 | 218025_s_at | -1.4753 | 0.4024 | |
| GSE77861 | ECI2 | 10455 | 218025_s_at | -0.3532 | 0.2722 | |
| GSE97050 | ECI2 | 10455 | A_23_P156852 | -0.2513 | 0.2395 | |
| SRP007169 | ECI2 | 10455 | RNAseq | 0.4627 | 0.2798 | |
| SRP008496 | ECI2 | 10455 | RNAseq | 0.4115 | 0.1129 | |
| SRP064894 | ECI2 | 10455 | RNAseq | 0.4687 | 0.1101 | |
| SRP133303 | ECI2 | 10455 | RNAseq | -0.2636 | 0.1475 | |
| SRP159526 | ECI2 | 10455 | RNAseq | 0.7768 | 0.0267 | |
| SRP193095 | ECI2 | 10455 | RNAseq | -0.4427 | 0.0073 | |
| SRP219564 | ECI2 | 10455 | RNAseq | -0.4627 | 0.3965 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ECI2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ECI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECI2 | 10455 | 4 | 5 | 21 | |
| GSE20123 | ECI2 | 10455 | 4 | 5 | 21 | |
| GSE43470 | ECI2 | 10455 | 8 | 2 | 33 | |
| GSE46452 | ECI2 | 10455 | 1 | 10 | 48 | |
| GSE47630 | ECI2 | 10455 | 7 | 8 | 25 | |
| GSE54993 | ECI2 | 10455 | 1 | 1 | 68 | |
| GSE54994 | ECI2 | 10455 | 10 | 3 | 40 | |
| GSE60625 | ECI2 | 10455 | 0 | 1 | 10 | |
| GSE74703 | ECI2 | 10455 | 7 | 2 | 27 | |
| GSE74704 | ECI2 | 10455 | 2 | 2 | 16 | |
| TCGA | ECI2 | 10455 | 16 | 29 | 51 |
Total number of gains: 60; Total number of losses: 68; Total Number of normals: 360.
Somatic mutations of ECI2:
Generating mutation plots.
Highly correlated genes for ECI2:
Showing top 20/273 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECI2 | SNX1 | 0.73519 | 3 | 0 | 3 |
| ECI2 | BTBD7 | 0.734036 | 3 | 0 | 3 |
| ECI2 | SUPT4H1 | 0.727863 | 4 | 0 | 4 |
| ECI2 | COPA | 0.720988 | 3 | 0 | 3 |
| ECI2 | CCNDBP1 | 0.715551 | 3 | 0 | 3 |
| ECI2 | GFM2 | 0.711599 | 3 | 0 | 3 |
| ECI2 | CALCOCO2 | 0.70632 | 3 | 0 | 3 |
| ECI2 | ARRDC3 | 0.703696 | 3 | 0 | 3 |
| ECI2 | DOCK7 | 0.703561 | 3 | 0 | 3 |
| ECI2 | HSBP1 | 0.68688 | 3 | 0 | 3 |
| ECI2 | PKN2 | 0.681792 | 3 | 0 | 3 |
| ECI2 | CCDC115 | 0.680284 | 3 | 0 | 3 |
| ECI2 | GBE1 | 0.679436 | 4 | 0 | 3 |
| ECI2 | DYRK3 | 0.678657 | 3 | 0 | 3 |
| ECI2 | GHITM | 0.673727 | 4 | 0 | 4 |
| ECI2 | XYLT1 | 0.672776 | 3 | 0 | 3 |
| ECI2 | SKP1 | 0.671476 | 5 | 0 | 4 |
| ECI2 | HNRNPA0 | 0.666833 | 5 | 0 | 4 |
| ECI2 | ARHGEF40 | 0.663462 | 4 | 0 | 3 |
| ECI2 | CRBN | 0.660977 | 4 | 0 | 3 |
For details and further investigation, click here
