| Full name: potassium channel tetramerization domain containing 10 | Alias Symbol: MSTP028|BTBD28 | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 83892 | HGNC ID: HGNC:23236 | Ensembl Gene: ENSG00000110906 | OMIM ID: 613421 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KCTD10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCTD10 | 83892 | 226518_at | -0.3919 | 0.4424 | |
| GSE26886 | KCTD10 | 83892 | 226518_at | -0.8444 | 0.0001 | |
| GSE45670 | KCTD10 | 83892 | 226518_at | -0.5142 | 0.0007 | |
| GSE53622 | KCTD10 | 83892 | 37810 | -0.3991 | 0.0000 | |
| GSE53624 | KCTD10 | 83892 | 37810 | -0.4275 | 0.0000 | |
| GSE63941 | KCTD10 | 83892 | 226518_at | -1.1160 | 0.0030 | |
| GSE77861 | KCTD10 | 83892 | 223208_at | 0.0273 | 0.8902 | |
| GSE97050 | KCTD10 | 83892 | A_24_P39101 | -0.2361 | 0.4342 | |
| SRP007169 | KCTD10 | 83892 | RNAseq | 0.9506 | 0.0252 | |
| SRP008496 | KCTD10 | 83892 | RNAseq | 0.8879 | 0.0100 | |
| SRP064894 | KCTD10 | 83892 | RNAseq | -0.0324 | 0.8661 | |
| SRP133303 | KCTD10 | 83892 | RNAseq | -0.0270 | 0.8664 | |
| SRP159526 | KCTD10 | 83892 | RNAseq | -0.2592 | 0.3843 | |
| SRP193095 | KCTD10 | 83892 | RNAseq | 0.0138 | 0.9085 | |
| SRP219564 | KCTD10 | 83892 | RNAseq | -0.1779 | 0.7197 | |
| TCGA | KCTD10 | 83892 | RNAseq | -0.0927 | 0.0747 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KCTD10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCTD10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCTD10 | 83892 | 5 | 3 | 22 | |
| GSE20123 | KCTD10 | 83892 | 5 | 4 | 21 | |
| GSE43470 | KCTD10 | 83892 | 2 | 1 | 40 | |
| GSE46452 | KCTD10 | 83892 | 9 | 1 | 49 | |
| GSE47630 | KCTD10 | 83892 | 9 | 1 | 30 | |
| GSE54993 | KCTD10 | 83892 | 0 | 5 | 65 | |
| GSE54994 | KCTD10 | 83892 | 4 | 3 | 46 | |
| GSE60625 | KCTD10 | 83892 | 0 | 0 | 11 | |
| GSE74703 | KCTD10 | 83892 | 2 | 0 | 34 | |
| GSE74704 | KCTD10 | 83892 | 2 | 2 | 16 | |
| TCGA | KCTD10 | 83892 | 21 | 10 | 65 |
Total number of gains: 59; Total number of losses: 30; Total Number of normals: 399.
Somatic mutations of KCTD10:
Generating mutation plots.
Highly correlated genes for KCTD10:
Showing top 20/892 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCTD10 | CCDC25 | 0.80009 | 3 | 0 | 3 |
| KCTD10 | NCS1 | 0.775399 | 3 | 0 | 3 |
| KCTD10 | THAP2 | 0.768949 | 4 | 0 | 4 |
| KCTD10 | ZFC3H1 | 0.766191 | 3 | 0 | 3 |
| KCTD10 | USP16 | 0.757942 | 3 | 0 | 3 |
| KCTD10 | RRAGB | 0.743913 | 3 | 0 | 3 |
| KCTD10 | RHBDF1 | 0.743651 | 3 | 0 | 3 |
| KCTD10 | CDK14 | 0.7412 | 3 | 0 | 3 |
| KCTD10 | MPP5 | 0.740913 | 3 | 0 | 3 |
| KCTD10 | SND1 | 0.738065 | 3 | 0 | 3 |
| KCTD10 | ABLIM2 | 0.736655 | 3 | 0 | 3 |
| KCTD10 | TMEM167B | 0.735658 | 5 | 0 | 5 |
| KCTD10 | CD200 | 0.730641 | 3 | 0 | 3 |
| KCTD10 | NCKAP1L | 0.728052 | 3 | 0 | 3 |
| KCTD10 | ZBTB4 | 0.727967 | 3 | 0 | 3 |
| KCTD10 | KCTD2 | 0.727166 | 3 | 0 | 3 |
| KCTD10 | CCDC159 | 0.722908 | 3 | 0 | 3 |
| KCTD10 | C16orf72 | 0.722356 | 4 | 0 | 4 |
| KCTD10 | MTMR9 | 0.720115 | 5 | 0 | 5 |
| KCTD10 | MAGI1 | 0.719675 | 3 | 0 | 3 |
For details and further investigation, click here
