| Full name: diphosphoinositol pentakisphosphate kinase 2 | Alias Symbol: KIAA0433|VIP2|CFAP160 | ||
| Type: protein-coding gene | Cytoband: 5q21.1 | ||
| Entrez ID: 23262 | HGNC ID: HGNC:29035 | Ensembl Gene: ENSG00000145725 | OMIM ID: 611648 |
| Drug and gene relationship at DGIdb | |||
Expression of PPIP5K2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPIP5K2 | 23262 | 203253_s_at | 0.1468 | 0.7348 | |
| GSE20347 | PPIP5K2 | 23262 | 203253_s_at | -0.4477 | 0.0034 | |
| GSE23400 | PPIP5K2 | 23262 | 203253_s_at | -0.0540 | 0.4683 | |
| GSE26886 | PPIP5K2 | 23262 | 203253_s_at | -0.8748 | 0.0122 | |
| GSE29001 | PPIP5K2 | 23262 | 203253_s_at | -0.3253 | 0.3485 | |
| GSE38129 | PPIP5K2 | 23262 | 203253_s_at | -0.2264 | 0.0798 | |
| GSE45670 | PPIP5K2 | 23262 | 203253_s_at | -0.2594 | 0.0707 | |
| GSE53622 | PPIP5K2 | 23262 | 120258 | -0.0854 | 0.3516 | |
| GSE53624 | PPIP5K2 | 23262 | 120258 | -0.2545 | 0.0000 | |
| GSE63941 | PPIP5K2 | 23262 | 203253_s_at | -1.6891 | 0.0007 | |
| GSE77861 | PPIP5K2 | 23262 | 203253_s_at | -0.8163 | 0.0163 | |
| GSE97050 | PPIP5K2 | 23262 | A_23_P213661 | 0.1480 | 0.5553 | |
| SRP007169 | PPIP5K2 | 23262 | RNAseq | -0.1332 | 0.7242 | |
| SRP008496 | PPIP5K2 | 23262 | RNAseq | 0.1437 | 0.5216 | |
| SRP064894 | PPIP5K2 | 23262 | RNAseq | -0.2339 | 0.3487 | |
| SRP133303 | PPIP5K2 | 23262 | RNAseq | -0.0067 | 0.9546 | |
| SRP159526 | PPIP5K2 | 23262 | RNAseq | -0.4823 | 0.0934 | |
| SRP193095 | PPIP5K2 | 23262 | RNAseq | -0.4493 | 0.0000 | |
| SRP219564 | PPIP5K2 | 23262 | RNAseq | -0.1866 | 0.5126 | |
| TCGA | PPIP5K2 | 23262 | RNAseq | -0.1599 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PPIP5K2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPIP5K2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPIP5K2 | 23262 | 1 | 13 | 16 | |
| GSE20123 | PPIP5K2 | 23262 | 1 | 13 | 16 | |
| GSE43470 | PPIP5K2 | 23262 | 3 | 9 | 31 | |
| GSE46452 | PPIP5K2 | 23262 | 0 | 28 | 31 | |
| GSE47630 | PPIP5K2 | 23262 | 0 | 20 | 20 | |
| GSE54993 | PPIP5K2 | 23262 | 8 | 1 | 61 | |
| GSE54994 | PPIP5K2 | 23262 | 1 | 17 | 35 | |
| GSE60625 | PPIP5K2 | 23262 | 0 | 0 | 11 | |
| GSE74703 | PPIP5K2 | 23262 | 2 | 7 | 27 | |
| GSE74704 | PPIP5K2 | 23262 | 1 | 7 | 12 | |
| TCGA | PPIP5K2 | 23262 | 2 | 43 | 51 |
Total number of gains: 19; Total number of losses: 158; Total Number of normals: 311.
Somatic mutations of PPIP5K2:
Generating mutation plots.
Highly correlated genes for PPIP5K2:
Showing top 20/874 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPIP5K2 | GPBP1 | 0.816595 | 3 | 0 | 3 |
| PPIP5K2 | TMEM167A | 0.814665 | 3 | 0 | 3 |
| PPIP5K2 | COPA | 0.794253 | 3 | 0 | 3 |
| PPIP5K2 | HSPA4 | 0.782212 | 4 | 0 | 4 |
| PPIP5K2 | IARS2 | 0.775862 | 3 | 0 | 3 |
| PPIP5K2 | TMEM117 | 0.770211 | 3 | 0 | 3 |
| PPIP5K2 | NSFL1C | 0.75941 | 3 | 0 | 3 |
| PPIP5K2 | PLIN2 | 0.756545 | 3 | 0 | 3 |
| PPIP5K2 | ZNF92 | 0.754759 | 3 | 0 | 3 |
| PPIP5K2 | SAMM50 | 0.752189 | 3 | 0 | 3 |
| PPIP5K2 | TTC39B | 0.751167 | 3 | 0 | 3 |
| PPIP5K2 | ZNF274 | 0.751066 | 4 | 0 | 4 |
| PPIP5K2 | MRPS18B | 0.747322 | 3 | 0 | 3 |
| PPIP5K2 | CTTNBP2NL | 0.742202 | 4 | 0 | 4 |
| PPIP5K2 | SRP9 | 0.741118 | 3 | 0 | 3 |
| PPIP5K2 | LRP11 | 0.738167 | 3 | 0 | 3 |
| PPIP5K2 | NDFIP2 | 0.735832 | 4 | 0 | 4 |
| PPIP5K2 | ZDHHC21 | 0.73058 | 3 | 0 | 3 |
| PPIP5K2 | ZNF441 | 0.729938 | 4 | 0 | 3 |
| PPIP5K2 | RAB18 | 0.728338 | 3 | 0 | 3 |
For details and further investigation, click here
