| Full name: KiSS-1 metastasis suppressor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 3814 | HGNC ID: HGNC:6341 | Ensembl Gene: ENSG00000170498 | OMIM ID: 603286 |
| Drug and gene relationship at DGIdb | |||
Expression of KISS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KISS1 | 3814 | 205563_at | 0.0127 | 0.9739 | |
| GSE20347 | KISS1 | 3814 | 205563_at | -0.0271 | 0.7240 | |
| GSE23400 | KISS1 | 3814 | 205563_at | -0.0633 | 0.2867 | |
| GSE26886 | KISS1 | 3814 | 205563_at | 0.2269 | 0.0658 | |
| GSE29001 | KISS1 | 3814 | 205563_at | -0.1449 | 0.2462 | |
| GSE38129 | KISS1 | 3814 | 205563_at | -0.0764 | 0.2254 | |
| GSE45670 | KISS1 | 3814 | 205563_at | 0.0184 | 0.8785 | |
| GSE53622 | KISS1 | 3814 | 79015 | 0.2672 | 0.0028 | |
| GSE53624 | KISS1 | 3814 | 79015 | 0.2917 | 0.0933 | |
| GSE63941 | KISS1 | 3814 | 205563_at | -0.1418 | 0.5244 | |
| GSE77861 | KISS1 | 3814 | 205563_at | -0.0484 | 0.5188 | |
| GSE97050 | KISS1 | 3814 | A_23_P124892 | -0.0210 | 0.9457 | |
| TCGA | KISS1 | 3814 | RNAseq | -0.7784 | 0.5941 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KISS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KISS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KISS1 | 3814 | 11 | 0 | 19 | |
| GSE20123 | KISS1 | 3814 | 11 | 0 | 19 | |
| GSE43470 | KISS1 | 3814 | 6 | 0 | 37 | |
| GSE46452 | KISS1 | 3814 | 3 | 1 | 55 | |
| GSE47630 | KISS1 | 3814 | 14 | 0 | 26 | |
| GSE54993 | KISS1 | 3814 | 0 | 6 | 64 | |
| GSE54994 | KISS1 | 3814 | 15 | 0 | 38 | |
| GSE60625 | KISS1 | 3814 | 0 | 0 | 11 | |
| GSE74703 | KISS1 | 3814 | 6 | 0 | 30 | |
| GSE74704 | KISS1 | 3814 | 5 | 0 | 15 | |
| TCGA | KISS1 | 3814 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of KISS1:
Generating mutation plots.
Highly correlated genes for KISS1:
Showing top 20/518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KISS1 | FAM222A-AS1 | 0.770711 | 3 | 0 | 3 |
| KISS1 | C16orf82 | 0.722263 | 3 | 0 | 3 |
| KISS1 | CDH23 | 0.700999 | 3 | 0 | 3 |
| KISS1 | TNF | 0.687558 | 3 | 0 | 3 |
| KISS1 | CD1B | 0.685242 | 6 | 0 | 5 |
| KISS1 | FAM71A | 0.673426 | 4 | 0 | 4 |
| KISS1 | ASIC4 | 0.671854 | 6 | 0 | 5 |
| KISS1 | HPX | 0.671073 | 7 | 0 | 7 |
| KISS1 | TMEM179 | 0.669887 | 5 | 0 | 4 |
| KISS1 | KRTAP4-8 | 0.662867 | 3 | 0 | 3 |
| KISS1 | C8A | 0.660102 | 4 | 0 | 3 |
| KISS1 | TMUB1 | 0.657239 | 3 | 0 | 3 |
| KISS1 | RBAKDN | 0.656096 | 4 | 0 | 3 |
| KISS1 | GUCA2B | 0.654779 | 5 | 0 | 4 |
| KISS1 | NR0B1 | 0.654433 | 3 | 0 | 3 |
| KISS1 | IHH | 0.65178 | 5 | 0 | 4 |
| KISS1 | DSCR4 | 0.648229 | 4 | 0 | 3 |
| KISS1 | OBSL1 | 0.647995 | 5 | 0 | 4 |
| KISS1 | LINC01341 | 0.64692 | 3 | 0 | 3 |
| KISS1 | NYX | 0.645364 | 8 | 0 | 8 |
For details and further investigation, click here
