| Full name: acid sensing ion channel subunit family member 4 | Alias Symbol: BNAC4 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 55515 | HGNC ID: HGNC:21263 | Ensembl Gene: ENSG00000072182 | OMIM ID: 606715 |
ASIC4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04750 | Inflammatory mediator regulation of TRP channels |
Expression of ASIC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASIC4 | 55515 | 221226_s_at | -0.0790 | 0.7780 | |
| GSE20347 | ASIC4 | 55515 | 221226_s_at | -0.1001 | 0.2462 | |
| GSE23400 | ASIC4 | 55515 | 221226_s_at | -0.2066 | 0.0000 | |
| GSE26886 | ASIC4 | 55515 | 221226_s_at | 0.2236 | 0.1037 | |
| GSE29001 | ASIC4 | 55515 | 221226_s_at | -0.2570 | 0.1319 | |
| GSE38129 | ASIC4 | 55515 | 221226_s_at | -0.1780 | 0.0479 | |
| GSE45670 | ASIC4 | 55515 | 221226_s_at | -0.0219 | 0.8768 | |
| GSE53622 | ASIC4 | 55515 | 107646 | 0.3070 | 0.0050 | |
| GSE53624 | ASIC4 | 55515 | 107646 | 0.2214 | 0.0623 | |
| GSE63941 | ASIC4 | 55515 | 221226_s_at | 0.5187 | 0.0001 | |
| GSE77861 | ASIC4 | 55515 | 221226_s_at | 0.0039 | 0.9750 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASIC4 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ASIC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASIC4 | 55515 | 2 | 14 | 14 | |
| GSE20123 | ASIC4 | 55515 | 2 | 13 | 15 | |
| GSE43470 | ASIC4 | 55515 | 1 | 6 | 36 | |
| GSE46452 | ASIC4 | 55515 | 0 | 5 | 54 | |
| GSE47630 | ASIC4 | 55515 | 4 | 5 | 31 | |
| GSE54993 | ASIC4 | 55515 | 1 | 2 | 67 | |
| GSE54994 | ASIC4 | 55515 | 8 | 9 | 36 | |
| GSE60625 | ASIC4 | 55515 | 0 | 3 | 8 | |
| GSE74703 | ASIC4 | 55515 | 1 | 5 | 30 | |
| GSE74704 | ASIC4 | 55515 | 2 | 7 | 11 | |
| TCGA | ASIC4 | 55515 | 13 | 25 | 58 |
Total number of gains: 34; Total number of losses: 94; Total Number of normals: 360.
Somatic mutations of ASIC4:
Generating mutation plots.
Highly correlated genes for ASIC4:
Showing top 20/1241 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASIC4 | SCGB1D1 | 0.766125 | 3 | 0 | 3 |
| ASIC4 | PHLDB1 | 0.746269 | 4 | 0 | 4 |
| ASIC4 | IRS4 | 0.737615 | 4 | 0 | 4 |
| ASIC4 | SLC9A3 | 0.732673 | 6 | 0 | 6 |
| ASIC4 | MASP2 | 0.72616 | 4 | 0 | 4 |
| ASIC4 | AMN | 0.71384 | 6 | 0 | 6 |
| ASIC4 | MUC3B | 0.707637 | 7 | 0 | 7 |
| ASIC4 | GDF2 | 0.707126 | 8 | 0 | 6 |
| ASIC4 | LRTM1 | 0.704335 | 5 | 0 | 5 |
| ASIC4 | CER1 | 0.702548 | 5 | 0 | 4 |
| ASIC4 | HAND1 | 0.701047 | 4 | 0 | 4 |
| ASIC4 | LINC00598 | 0.699528 | 4 | 0 | 4 |
| ASIC4 | ZMAT4 | 0.698352 | 4 | 0 | 4 |
| ASIC4 | PI16 | 0.695145 | 3 | 0 | 3 |
| ASIC4 | MSH4 | 0.690601 | 3 | 0 | 3 |
| ASIC4 | ABCC2 | 0.689531 | 3 | 0 | 3 |
| ASIC4 | FRMPD4 | 0.688586 | 5 | 0 | 5 |
| ASIC4 | FGF23 | 0.687397 | 4 | 0 | 4 |
| ASIC4 | NEUROD6 | 0.686165 | 6 | 0 | 6 |
| ASIC4 | CNTD1 | 0.684121 | 3 | 0 | 3 |
For details and further investigation, click here
