KRT27

 

Full name: keratin 27 Alias Symbol: 
Type: protein-coding gene Cytoband: 17q21.2
Entrez ID: 342574 HGNC ID: HGNC:30841 Ensembl Gene: ENSG00000171446 OMIM ID: 616676
Drug and gene relationship at DGIdb

 

Expression of KRT27:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KRT27 342574 240388_at 0.0437 0.8977
GSE26886 KRT27 342574 240388_at 0.0826 0.3378
GSE45670 KRT27 342574 240388_at -0.0752 0.5566
GSE53622 KRT27 342574 66620 0.2935 0.0524
GSE53624 KRT27 342574 66620 0.0258 0.8938
GSE63941 KRT27 342574 240388_at -0.0288 0.8658
GSE77861 KRT27 342574 240388_at -0.1034 0.3073
SRP007169 KRT27 342574 RNAseq 1.9253 0.0444
TCGA KRT27 342574 RNAseq 0.1760 0.8978

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by KRT27 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KRT27:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KRT27 342574 7 1 22
GSE20123 KRT27 342574 7 1 22
GSE43470 KRT27 342574 1 2 40
GSE46452 KRT27 342574 34 0 25
GSE47630 KRT27 342574 8 1 31
GSE54993 KRT27 342574 3 4 63
GSE54994 KRT27 342574 8 5 40
GSE60625 KRT27 342574 4 0 7
GSE74703 KRT27 342574 1 1 34
GSE74704 KRT27 342574 5 1 14
TCGA KRT27 342574 22 8 66

Total number of gains: 100; Total number of losses: 24; Total Number of normals: 364.  

 

Somatic mutations of KRT27:

 

Generating mutation plots.

 

Highly correlated genes for KRT27:

 

Showing all 16 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KRT27OR52A10.665117303
KRT27ENDOV0.650379303
KRT27GJA80.598525404
KRT27NAA600.597401303
KRT27ACTL7A0.580357303
KRT27FAM171A20.576437403
KRT27MIOX0.56738403
KRT27RDH80.56307303
KRT27DAO0.543009403
KRT27KCNJ130.540545403
KRT27MPND0.531079503
KRT27OR8D20.524627403
KRT27LDHAL6A0.521294403
KRT27ATP1A30.521007503
KRT27CACNG50.510805403
KRT27LHPP0.505009503

For details and further investigation, click here