ACTL7A

 

Full name: actin like 7A Alias Symbol: 
Type: protein-coding gene Cytoband: 9q31.3
Entrez ID: 10881 HGNC ID: HGNC:161 Ensembl Gene: ENSG00000187003 OMIM ID: 604303
Drug and gene relationship at DGIdb

 

Expression of ACTL7A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ACTL7A 10881 220501_at -0.0036 0.9927
GSE20347 ACTL7A 10881 220501_at 0.0161 0.8819
GSE23400 ACTL7A 10881 220501_at -0.1466 0.0001
GSE26886 ACTL7A 10881 220501_at 0.0909 0.5145
GSE29001 ACTL7A 10881 220501_at -0.1497 0.2901
GSE38129 ACTL7A 10881 220501_at -0.0770 0.2989
GSE45670 ACTL7A 10881 220501_at 0.0808 0.4371
GSE53622 ACTL7A 10881 25437 0.4688 0.0000
GSE53624 ACTL7A 10881 25437 0.8994 0.0000
GSE63941 ACTL7A 10881 220501_at 0.3002 0.0760
GSE77861 ACTL7A 10881 220501_at -0.1856 0.1492

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ACTL7A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ACTL7A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ACTL7A 10881 4 9 17
GSE20123 ACTL7A 10881 5 8 17
GSE43470 ACTL7A 10881 7 3 33
GSE46452 ACTL7A 10881 6 13 40
GSE47630 ACTL7A 10881 3 16 21
GSE54993 ACTL7A 10881 3 3 64
GSE54994 ACTL7A 10881 9 10 34
GSE60625 ACTL7A 10881 0 0 11
GSE74703 ACTL7A 10881 6 3 27
GSE74704 ACTL7A 10881 2 6 12
TCGA ACTL7A 10881 27 21 48

Total number of gains: 72; Total number of losses: 92; Total Number of normals: 324.  


 

Somatic mutations of ACTL7A:

 

Generating mutation plots.

 

Highly correlated genes for ACTL7A:

 

Showing top 20/605 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ACTL7AIFT1220.684392403
ACTL7AVGLL20.669442404
ACTL7ASLC22A120.660353303
ACTL7AOVCH1-AS10.655114303
ACTL7AWNT60.650955706
ACTL7APTPRN20.650433504
ACTL7AASB170.641574303
ACTL7ARABEP20.640201403
ACTL7ATULP10.640014404
ACTL7AOPTC0.637638403
ACTL7ACRHR20.633346605
ACTL7ATAC30.631564706
ACTL7ACASC170.631478403
ACTL7ASCNN1G0.631371505
ACTL7APRAMEF110.626849908
ACTL7AGP90.626748908
ACTL7AOVGP10.626311504
ACTL7AKRT370.625694404
ACTL7AABCC20.62356404
ACTL7AMIOX0.621821504

For details and further investigation, click here