| Full name: MPN domain containing | Alias Symbol: FLJ14981 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 84954 | HGNC ID: HGNC:25934 | Ensembl Gene: ENSG00000008382 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MPND:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPND | 84954 | 233651_s_at | -0.1593 | 0.7192 | |
| GSE26886 | MPND | 84954 | 233651_s_at | -0.3086 | 0.1625 | |
| GSE45670 | MPND | 84954 | 233651_s_at | -0.1470 | 0.2357 | |
| GSE53622 | MPND | 84954 | 53728 | -0.1238 | 0.0065 | |
| GSE53624 | MPND | 84954 | 53728 | -0.1902 | 0.0000 | |
| GSE63941 | MPND | 84954 | 233651_s_at | 0.4404 | 0.3627 | |
| GSE77861 | MPND | 84954 | 233651_s_at | -0.2164 | 0.2046 | |
| GSE97050 | MPND | 84954 | A_24_P44931 | -0.0050 | 0.9830 | |
| SRP007169 | MPND | 84954 | RNAseq | -0.9986 | 0.0188 | |
| SRP008496 | MPND | 84954 | RNAseq | -0.7995 | 0.0020 | |
| SRP064894 | MPND | 84954 | RNAseq | 0.1035 | 0.7528 | |
| SRP133303 | MPND | 84954 | RNAseq | -0.7082 | 0.0005 | |
| SRP159526 | MPND | 84954 | RNAseq | -0.2134 | 0.3205 | |
| SRP193095 | MPND | 84954 | RNAseq | -0.7841 | 0.0000 | |
| SRP219564 | MPND | 84954 | RNAseq | -0.1696 | 0.5990 | |
| TCGA | MPND | 84954 | RNAseq | -0.1666 | 0.0173 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPND expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPND:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPND | 84954 | 5 | 3 | 22 | |
| GSE20123 | MPND | 84954 | 4 | 2 | 24 | |
| GSE43470 | MPND | 84954 | 1 | 8 | 34 | |
| GSE46452 | MPND | 84954 | 47 | 1 | 11 | |
| GSE47630 | MPND | 84954 | 5 | 7 | 28 | |
| GSE54993 | MPND | 84954 | 16 | 3 | 51 | |
| GSE54994 | MPND | 84954 | 6 | 16 | 31 | |
| GSE60625 | MPND | 84954 | 9 | 0 | 2 | |
| GSE74703 | MPND | 84954 | 1 | 5 | 30 | |
| GSE74704 | MPND | 84954 | 1 | 2 | 17 | |
| TCGA | MPND | 84954 | 10 | 19 | 67 |
Total number of gains: 105; Total number of losses: 66; Total Number of normals: 317.
Somatic mutations of MPND:
Generating mutation plots.
Highly correlated genes for MPND:
Showing top 20/163 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPND | UBE2NL | 0.82136 | 3 | 0 | 3 |
| MPND | ZNF862 | 0.787311 | 3 | 0 | 3 |
| MPND | SIK2 | 0.765498 | 3 | 0 | 3 |
| MPND | ERCC2 | 0.764347 | 3 | 0 | 3 |
| MPND | PPP1R11 | 0.763967 | 3 | 0 | 3 |
| MPND | HDAC6 | 0.740758 | 3 | 0 | 3 |
| MPND | RABL3 | 0.738068 | 3 | 0 | 3 |
| MPND | RABEP2 | 0.736408 | 3 | 0 | 3 |
| MPND | RNFT2 | 0.72961 | 3 | 0 | 3 |
| MPND | BLOC1S1 | 0.727436 | 4 | 0 | 4 |
| MPND | CDC37 | 0.723945 | 3 | 0 | 3 |
| MPND | ALKBH7 | 0.707623 | 5 | 0 | 5 |
| MPND | HSD17B10 | 0.703937 | 3 | 0 | 3 |
| MPND | WHAMM | 0.70108 | 3 | 0 | 3 |
| MPND | PPP1R9A | 0.699478 | 3 | 0 | 3 |
| MPND | FBXW9 | 0.696439 | 3 | 0 | 3 |
| MPND | CHCHD6 | 0.69507 | 3 | 0 | 3 |
| MPND | CRADD | 0.692543 | 4 | 0 | 4 |
| MPND | ZNF837 | 0.690415 | 4 | 0 | 3 |
| MPND | DNAJB12 | 0.689011 | 3 | 0 | 3 |
For details and further investigation, click here
