| Full name: myo-inositol oxygenase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 55586 | HGNC ID: HGNC:14522 | Ensembl Gene: ENSG00000100253 | OMIM ID: 606774 |
| Drug and gene relationship at DGIdb | |||
Expression of MIOX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIOX | 55586 | 224179_s_at | 0.0614 | 0.8617 | |
| GSE26886 | MIOX | 55586 | 224179_s_at | 0.3763 | 0.0079 | |
| GSE45670 | MIOX | 55586 | 224179_s_at | 0.0001 | 0.9992 | |
| GSE53622 | MIOX | 55586 | 96055 | 0.0418 | 0.7741 | |
| GSE53624 | MIOX | 55586 | 96055 | 0.2931 | 0.0040 | |
| GSE63941 | MIOX | 55586 | 224179_s_at | 0.1798 | 0.3765 | |
| GSE77861 | MIOX | 55586 | 224179_s_at | -0.1691 | 0.2363 | |
| GSE97050 | MIOX | 55586 | A_33_P3355281 | -0.0233 | 0.9379 | |
| SRP133303 | MIOX | 55586 | RNAseq | 0.0708 | 0.7815 | |
| SRP219564 | MIOX | 55586 | RNAseq | 1.0939 | 0.0930 | |
| TCGA | MIOX | 55586 | RNAseq | 1.6184 | 0.1740 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MIOX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MIOX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIOX | 55586 | 3 | 8 | 19 | |
| GSE20123 | MIOX | 55586 | 3 | 8 | 19 | |
| GSE43470 | MIOX | 55586 | 2 | 8 | 33 | |
| GSE46452 | MIOX | 55586 | 31 | 2 | 26 | |
| GSE47630 | MIOX | 55586 | 9 | 4 | 27 | |
| GSE54993 | MIOX | 55586 | 4 | 6 | 60 | |
| GSE54994 | MIOX | 55586 | 11 | 8 | 34 | |
| GSE60625 | MIOX | 55586 | 5 | 0 | 6 | |
| GSE74703 | MIOX | 55586 | 2 | 6 | 28 | |
| GSE74704 | MIOX | 55586 | 1 | 4 | 15 | |
| TCGA | MIOX | 55586 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of MIOX:
Generating mutation plots.
Highly correlated genes for MIOX:
Showing top 20/181 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIOX | CACNA1S | 0.803165 | 3 | 0 | 3 |
| MIOX | RAPGEF3 | 0.702303 | 3 | 0 | 3 |
| MIOX | LINC00917 | 0.694879 | 3 | 0 | 3 |
| MIOX | GAL3ST1 | 0.693997 | 3 | 0 | 3 |
| MIOX | TTC9B | 0.683087 | 3 | 0 | 3 |
| MIOX | UCN3 | 0.681296 | 3 | 0 | 3 |
| MIOX | C10orf62 | 0.679485 | 3 | 0 | 3 |
| MIOX | ATP1A3 | 0.669375 | 4 | 0 | 3 |
| MIOX | C19orf57 | 0.667573 | 3 | 0 | 3 |
| MIOX | ASCL5 | 0.665474 | 3 | 0 | 3 |
| MIOX | ASB12 | 0.662929 | 3 | 0 | 3 |
| MIOX | C1orf127 | 0.661224 | 4 | 0 | 4 |
| MIOX | C16orf86 | 0.660183 | 4 | 0 | 4 |
| MIOX | LINC00886 | 0.649945 | 3 | 0 | 3 |
| MIOX | NT5M | 0.649782 | 3 | 0 | 3 |
| MIOX | PRPS1L1 | 0.645608 | 3 | 0 | 3 |
| MIOX | COL11A2 | 0.640115 | 3 | 0 | 3 |
| MIOX | NEBL-AS1 | 0.638713 | 3 | 0 | 3 |
| MIOX | DCST1 | 0.63864 | 3 | 0 | 3 |
| MIOX | GDF11 | 0.632904 | 4 | 0 | 4 |
For details and further investigation, click here
