| Full name: retinol dehydrogenase 8 | Alias Symbol: PRRDH|SDR28C2 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 50700 | HGNC ID: HGNC:14423 | Ensembl Gene: | OMIM ID: 608575 |
| Drug and gene relationship at DGIdb | |||
Expression of RDH8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RDH8 | 50700 | 220683_at | -0.1360 | 0.6005 | |
| GSE20347 | RDH8 | 50700 | 220683_at | -0.0021 | 0.9794 | |
| GSE23400 | RDH8 | 50700 | 220683_at | -0.1442 | 0.0000 | |
| GSE26886 | RDH8 | 50700 | 220683_at | -0.0541 | 0.6862 | |
| GSE29001 | RDH8 | 50700 | 220683_at | -0.1868 | 0.0893 | |
| GSE38129 | RDH8 | 50700 | 220683_at | -0.0058 | 0.9327 | |
| GSE45670 | RDH8 | 50700 | 220683_at | 0.0401 | 0.7261 | |
| GSE63941 | RDH8 | 50700 | 220683_at | -0.1046 | 0.4887 | |
| GSE77861 | RDH8 | 50700 | 220683_at | -0.1131 | 0.3972 | |
| GSE97050 | RDH8 | 50700 | A_23_P50291 | -0.3465 | 0.3790 | |
| TCGA | RDH8 | 50700 | RNAseq | 1.2191 | 0.2641 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RDH8 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RDH8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RDH8 | 50700 | 4 | 2 | 24 | |
| GSE20123 | RDH8 | 50700 | 3 | 1 | 26 | |
| GSE43470 | RDH8 | 50700 | 3 | 6 | 34 | |
| GSE46452 | RDH8 | 50700 | 47 | 1 | 11 | |
| GSE47630 | RDH8 | 50700 | 4 | 7 | 29 | |
| GSE54993 | RDH8 | 50700 | 16 | 3 | 51 | |
| GSE54994 | RDH8 | 50700 | 7 | 13 | 33 | |
| GSE60625 | RDH8 | 50700 | 9 | 0 | 2 | |
| GSE74703 | RDH8 | 50700 | 3 | 4 | 29 | |
| GSE74704 | RDH8 | 50700 | 0 | 1 | 19 | |
| TCGA | RDH8 | 50700 | 12 | 17 | 67 |
Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.
Somatic mutations of RDH8:
Generating mutation plots.
Highly correlated genes for RDH8:
Showing top 20/659 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RDH8 | CABP1 | 0.743719 | 3 | 0 | 3 |
| RDH8 | GRID2 | 0.685442 | 3 | 0 | 3 |
| RDH8 | PPP1R3F | 0.680299 | 3 | 0 | 3 |
| RDH8 | MYOM3 | 0.674938 | 3 | 0 | 3 |
| RDH8 | LCN8 | 0.672794 | 3 | 0 | 3 |
| RDH8 | LIPF | 0.671248 | 3 | 0 | 3 |
| RDH8 | CASQ1 | 0.658556 | 3 | 0 | 3 |
| RDH8 | ZG16 | 0.656855 | 4 | 0 | 4 |
| RDH8 | DPEP1 | 0.655851 | 5 | 0 | 4 |
| RDH8 | CER1 | 0.65501 | 4 | 0 | 4 |
| RDH8 | OVGP1 | 0.649648 | 4 | 0 | 4 |
| RDH8 | TMEM105 | 0.649573 | 3 | 0 | 3 |
| RDH8 | IQCJ-SCHIP1-AS1 | 0.645934 | 3 | 0 | 3 |
| RDH8 | KCNMB2 | 0.645422 | 4 | 0 | 4 |
| RDH8 | FGF21 | 0.642267 | 5 | 0 | 4 |
| RDH8 | TSSK2 | 0.64154 | 5 | 0 | 4 |
| RDH8 | BARHL1 | 0.641202 | 4 | 0 | 3 |
| RDH8 | ANKRD1 | 0.639259 | 3 | 0 | 3 |
| RDH8 | GAS8 | 0.638535 | 5 | 0 | 4 |
| RDH8 | CAV3 | 0.636219 | 5 | 0 | 4 |
For details and further investigation, click here
