| Full name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | Alias Symbol: bA427L11.3|POLYDOM|FLJ13529 | ||
| Type: protein-coding gene | Cytoband: 9q31.3 | ||
| Entrez ID: 79987 | HGNC ID: HGNC:15985 | Ensembl Gene: ENSG00000165124 | OMIM ID: 611691 |
| Drug and gene relationship at DGIdb | |||
Expression of SVEP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SVEP1 | 79987 | 213247_at | -0.9390 | 0.1821 | |
| GSE20347 | SVEP1 | 79987 | 213247_at | 0.3140 | 0.0032 | |
| GSE23400 | SVEP1 | 79987 | 213247_at | -0.1939 | 0.0030 | |
| GSE26886 | SVEP1 | 79987 | 213247_at | 0.2539 | 0.3153 | |
| GSE29001 | SVEP1 | 79987 | 213247_at | 0.2734 | 0.1656 | |
| GSE38129 | SVEP1 | 79987 | 213247_at | -0.3628 | 0.0814 | |
| GSE45670 | SVEP1 | 79987 | 213247_at | -1.6730 | 0.0000 | |
| GSE53622 | SVEP1 | 79987 | 124916 | -0.5021 | 0.0134 | |
| GSE53624 | SVEP1 | 79987 | 124916 | 0.0874 | 0.6603 | |
| GSE63941 | SVEP1 | 79987 | 213247_at | -5.2872 | 0.0000 | |
| GSE77861 | SVEP1 | 79987 | 213247_at | 0.2015 | 0.1861 | |
| GSE97050 | SVEP1 | 79987 | A_23_P216596 | -0.0269 | 0.9535 | |
| SRP007169 | SVEP1 | 79987 | RNAseq | 2.0388 | 0.0001 | |
| SRP008496 | SVEP1 | 79987 | RNAseq | 2.4923 | 0.0000 | |
| SRP064894 | SVEP1 | 79987 | RNAseq | -0.7362 | 0.0564 | |
| SRP133303 | SVEP1 | 79987 | RNAseq | -0.7664 | 0.0206 | |
| SRP159526 | SVEP1 | 79987 | RNAseq | -0.4283 | 0.2762 | |
| SRP193095 | SVEP1 | 79987 | RNAseq | 1.2118 | 0.0003 | |
| SRP219564 | SVEP1 | 79987 | RNAseq | -0.4318 | 0.6579 | |
| TCGA | SVEP1 | 79987 | RNAseq | -0.4641 | 0.0001 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by SVEP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SVEP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SVEP1 | 79987 | 6 | 10 | 14 | |
| GSE20123 | SVEP1 | 79987 | 6 | 9 | 15 | |
| GSE43470 | SVEP1 | 79987 | 4 | 3 | 36 | |
| GSE46452 | SVEP1 | 79987 | 6 | 13 | 40 | |
| GSE47630 | SVEP1 | 79987 | 3 | 16 | 21 | |
| GSE54993 | SVEP1 | 79987 | 3 | 3 | 64 | |
| GSE54994 | SVEP1 | 79987 | 9 | 10 | 34 | |
| GSE60625 | SVEP1 | 79987 | 0 | 0 | 11 | |
| GSE74703 | SVEP1 | 79987 | 4 | 3 | 29 | |
| GSE74704 | SVEP1 | 79987 | 3 | 6 | 11 | |
| TCGA | SVEP1 | 79987 | 25 | 22 | 49 |
Total number of gains: 69; Total number of losses: 95; Total Number of normals: 324.
Somatic mutations of SVEP1:
Generating mutation plots.
Highly correlated genes for SVEP1:
Showing top 20/922 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SVEP1 | AFF3 | 0.884073 | 3 | 0 | 3 |
| SVEP1 | FIBIN | 0.87184 | 4 | 0 | 4 |
| SVEP1 | LINC01279 | 0.857852 | 3 | 0 | 3 |
| SVEP1 | LRRN4CL | 0.82953 | 6 | 0 | 6 |
| SVEP1 | ZNF583 | 0.821111 | 3 | 0 | 3 |
| SVEP1 | MGARP | 0.81129 | 3 | 0 | 3 |
| SVEP1 | CCDC80 | 0.78887 | 6 | 0 | 6 |
| SVEP1 | AGTR1 | 0.785934 | 8 | 0 | 8 |
| SVEP1 | ZBTB16 | 0.780623 | 5 | 0 | 5 |
| SVEP1 | SPATA9 | 0.777373 | 3 | 0 | 3 |
| SVEP1 | STARD9 | 0.776839 | 4 | 0 | 4 |
| SVEP1 | SNX25 | 0.768219 | 3 | 0 | 3 |
| SVEP1 | PLP1 | 0.766795 | 5 | 0 | 5 |
| SVEP1 | MRGPRF | 0.766502 | 6 | 0 | 6 |
| SVEP1 | FAM13C | 0.76455 | 4 | 0 | 4 |
| SVEP1 | SLC4A4 | 0.762504 | 5 | 0 | 4 |
| SVEP1 | DEXI | 0.762123 | 3 | 0 | 3 |
| SVEP1 | DCHS1 | 0.75971 | 6 | 0 | 6 |
| SVEP1 | CYP4V2 | 0.754186 | 4 | 0 | 4 |
| SVEP1 | ADAMTS9-AS2 | 0.753799 | 4 | 0 | 4 |
For details and further investigation, click here
