| Full name: neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q36.3 | ||
| Entrez ID: 57624 | HGNC ID: HGNC:29291 | Ensembl Gene: ENSG00000144460 | OMIM ID: 615478 |
| Drug and gene relationship at DGIdb | |||
Expression of NYAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NYAP2 | 57624 | 233916_at | -0.0536 | 0.8050 | |
| GSE26886 | NYAP2 | 57624 | 233916_at | -0.1330 | 0.2254 | |
| GSE45670 | NYAP2 | 57624 | 233916_at | 0.3862 | 0.0482 | |
| GSE53622 | NYAP2 | 57624 | 82596 | -0.0964 | 0.4139 | |
| GSE53624 | NYAP2 | 57624 | 82596 | -0.3095 | 0.0008 | |
| GSE63941 | NYAP2 | 57624 | 233916_at | 0.0059 | 0.9765 | |
| GSE77861 | NYAP2 | 57624 | 233916_at | -0.0669 | 0.5524 | |
| SRP133303 | NYAP2 | 57624 | RNAseq | 0.2476 | 0.5652 | |
| SRP159526 | NYAP2 | 57624 | RNAseq | -2.6747 | 0.0009 | |
| SRP193095 | NYAP2 | 57624 | RNAseq | -0.7298 | 0.0333 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NYAP2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NYAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NYAP2 | 57624 | 2 | 12 | 16 | |
| GSE20123 | NYAP2 | 57624 | 2 | 12 | 16 | |
| GSE43470 | NYAP2 | 57624 | 0 | 7 | 36 | |
| GSE46452 | NYAP2 | 57624 | 0 | 5 | 54 | |
| GSE47630 | NYAP2 | 57624 | 4 | 5 | 31 | |
| GSE54993 | NYAP2 | 57624 | 1 | 2 | 67 | |
| GSE54994 | NYAP2 | 57624 | 6 | 10 | 37 | |
| GSE60625 | NYAP2 | 57624 | 0 | 3 | 8 | |
| GSE74703 | NYAP2 | 57624 | 0 | 6 | 30 | |
| GSE74704 | NYAP2 | 57624 | 2 | 6 | 12 | |
| TCGA | NYAP2 | 57624 | 14 | 26 | 56 |
Total number of gains: 31; Total number of losses: 94; Total Number of normals: 363.
Somatic mutations of NYAP2:
Generating mutation plots.
Highly correlated genes for NYAP2:
Showing top 20/79 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NYAP2 | GPR6 | 0.696933 | 3 | 0 | 3 |
| NYAP2 | TMEM169 | 0.693119 | 3 | 0 | 3 |
| NYAP2 | KRT37 | 0.688824 | 3 | 0 | 3 |
| NYAP2 | TECTB | 0.68861 | 4 | 0 | 4 |
| NYAP2 | GPR50 | 0.675949 | 3 | 0 | 3 |
| NYAP2 | CRB2 | 0.674505 | 3 | 0 | 3 |
| NYAP2 | CNR2 | 0.662988 | 4 | 0 | 4 |
| NYAP2 | KRTAP1-5 | 0.65851 | 3 | 0 | 3 |
| NYAP2 | CA1 | 0.651699 | 3 | 0 | 3 |
| NYAP2 | NFIA-AS2 | 0.641942 | 3 | 0 | 3 |
| NYAP2 | DLGAP2 | 0.641569 | 3 | 0 | 3 |
| NYAP2 | LRRC3 | 0.63807 | 3 | 0 | 3 |
| NYAP2 | IL25 | 0.637052 | 3 | 0 | 3 |
| NYAP2 | ARHGAP22-IT1 | 0.625622 | 3 | 0 | 3 |
| NYAP2 | ASB10 | 0.62459 | 3 | 0 | 3 |
| NYAP2 | FANCD2OS | 0.618085 | 4 | 0 | 3 |
| NYAP2 | LINC01118 | 0.617837 | 3 | 0 | 3 |
| NYAP2 | SPACA1 | 0.613019 | 3 | 0 | 3 |
| NYAP2 | SAMD15 | 0.612105 | 3 | 0 | 3 |
| NYAP2 | PCGEM1 | 0.603326 | 4 | 0 | 4 |
For details and further investigation, click here
