| Full name: erythrocyte membrane protein band 4.1 like 2 | Alias Symbol: 4.1-G | ||
| Type: protein-coding gene | Cytoband: 6q23.1-q23.2 | ||
| Entrez ID: 2037 | HGNC ID: HGNC:3379 | Ensembl Gene: ENSG00000079819 | OMIM ID: 603237 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
EPB41L2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of EPB41L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPB41L2 | 2037 | 201719_s_at | -0.5078 | 0.3321 | |
| GSE20347 | EPB41L2 | 2037 | 201719_s_at | 0.2205 | 0.4344 | |
| GSE23400 | EPB41L2 | 2037 | 201719_s_at | 0.0177 | 0.8991 | |
| GSE26886 | EPB41L2 | 2037 | 201719_s_at | 0.9949 | 0.0142 | |
| GSE29001 | EPB41L2 | 2037 | 201719_s_at | 0.3563 | 0.4370 | |
| GSE38129 | EPB41L2 | 2037 | 201719_s_at | -0.1580 | 0.6641 | |
| GSE45670 | EPB41L2 | 2037 | 201719_s_at | -1.2845 | 0.0001 | |
| GSE53622 | EPB41L2 | 2037 | 37211 | -0.2418 | 0.0257 | |
| GSE53624 | EPB41L2 | 2037 | 37211 | -0.1265 | 0.1528 | |
| GSE63941 | EPB41L2 | 2037 | 201719_s_at | -3.3428 | 0.0022 | |
| GSE77861 | EPB41L2 | 2037 | 242092_at | -0.0944 | 0.5895 | |
| GSE97050 | EPB41L2 | 2037 | A_23_P134109 | -0.4486 | 0.2495 | |
| SRP007169 | EPB41L2 | 2037 | RNAseq | 2.8116 | 0.0000 | |
| SRP008496 | EPB41L2 | 2037 | RNAseq | 2.7424 | 0.0000 | |
| SRP064894 | EPB41L2 | 2037 | RNAseq | 0.0591 | 0.8472 | |
| SRP133303 | EPB41L2 | 2037 | RNAseq | -0.2790 | 0.1636 | |
| SRP159526 | EPB41L2 | 2037 | RNAseq | 0.2811 | 0.4179 | |
| SRP193095 | EPB41L2 | 2037 | RNAseq | 0.1533 | 0.5064 | |
| SRP219564 | EPB41L2 | 2037 | RNAseq | -0.0017 | 0.9981 | |
| TCGA | EPB41L2 | 2037 | RNAseq | -0.2381 | 0.0045 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by EPB41L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPB41L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPB41L2 | 2037 | 1 | 4 | 25 | |
| GSE20123 | EPB41L2 | 2037 | 1 | 3 | 26 | |
| GSE43470 | EPB41L2 | 2037 | 5 | 0 | 38 | |
| GSE46452 | EPB41L2 | 2037 | 2 | 11 | 46 | |
| GSE47630 | EPB41L2 | 2037 | 9 | 4 | 27 | |
| GSE54993 | EPB41L2 | 2037 | 3 | 3 | 64 | |
| GSE54994 | EPB41L2 | 2037 | 9 | 7 | 37 | |
| GSE60625 | EPB41L2 | 2037 | 0 | 1 | 10 | |
| GSE74703 | EPB41L2 | 2037 | 4 | 0 | 32 | |
| GSE74704 | EPB41L2 | 2037 | 0 | 1 | 19 | |
| TCGA | EPB41L2 | 2037 | 11 | 19 | 66 |
Total number of gains: 45; Total number of losses: 53; Total Number of normals: 390.
Somatic mutations of EPB41L2:
Generating mutation plots.
Highly correlated genes for EPB41L2:
Showing top 20/1025 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPB41L2 | FNIP2 | 0.797627 | 3 | 0 | 3 |
| EPB41L2 | RNASE4 | 0.786261 | 5 | 0 | 5 |
| EPB41L2 | TSPAN18 | 0.766015 | 5 | 0 | 5 |
| EPB41L2 | SLIT3 | 0.754557 | 5 | 0 | 4 |
| EPB41L2 | ZEB1 | 0.750577 | 3 | 0 | 3 |
| EPB41L2 | DIXDC1 | 0.745486 | 8 | 0 | 8 |
| EPB41L2 | KIAA1143 | 0.740351 | 3 | 0 | 3 |
| EPB41L2 | MGARP | 0.738014 | 3 | 0 | 3 |
| EPB41L2 | AKT3 | 0.726576 | 11 | 0 | 11 |
| EPB41L2 | INMT | 0.724969 | 6 | 0 | 5 |
| EPB41L2 | PLP1 | 0.720684 | 6 | 0 | 6 |
| EPB41L2 | MRVI1 | 0.715705 | 7 | 0 | 7 |
| EPB41L2 | SLC4A4 | 0.715691 | 5 | 0 | 5 |
| EPB41L2 | MYADM | 0.714594 | 5 | 0 | 5 |
| EPB41L2 | EID3 | 0.71331 | 4 | 0 | 4 |
| EPB41L2 | PEG3 | 0.709767 | 6 | 0 | 6 |
| EPB41L2 | DNAJC18 | 0.708028 | 4 | 0 | 3 |
| EPB41L2 | EDNRB | 0.707586 | 8 | 0 | 8 |
| EPB41L2 | DNM3OS | 0.707522 | 3 | 0 | 3 |
| EPB41L2 | FIBIN | 0.706241 | 5 | 0 | 4 |
For details and further investigation, click here
