| Full name: contactin associated protein 1 | Alias Symbol: p190|Caspr|CNTNAP | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 8506 | HGNC ID: HGNC:8011 | Ensembl Gene: ENSG00000108797 | OMIM ID: 602346 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CNTNAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNTNAP1 | 8506 | 219400_at | -0.1371 | 0.7709 | |
| GSE20347 | CNTNAP1 | 8506 | 219400_at | 0.1260 | 0.2513 | |
| GSE23400 | CNTNAP1 | 8506 | 219400_at | -0.1550 | 0.0025 | |
| GSE26886 | CNTNAP1 | 8506 | 219400_at | 0.1728 | 0.1975 | |
| GSE29001 | CNTNAP1 | 8506 | 219400_at | -0.0961 | 0.7036 | |
| GSE38129 | CNTNAP1 | 8506 | 219400_at | -0.0622 | 0.6843 | |
| GSE45670 | CNTNAP1 | 8506 | 219400_at | -0.0579 | 0.5268 | |
| GSE53622 | CNTNAP1 | 8506 | 11149 | 0.3430 | 0.0001 | |
| GSE53624 | CNTNAP1 | 8506 | 11149 | 0.0421 | 0.6567 | |
| GSE63941 | CNTNAP1 | 8506 | 219400_at | -0.9401 | 0.0100 | |
| GSE77861 | CNTNAP1 | 8506 | 219400_at | 0.0974 | 0.4585 | |
| GSE97050 | CNTNAP1 | 8506 | A_23_P411113 | 0.2081 | 0.4638 | |
| SRP007169 | CNTNAP1 | 8506 | RNAseq | 2.7866 | 0.0113 | |
| SRP064894 | CNTNAP1 | 8506 | RNAseq | 1.0780 | 0.0043 | |
| SRP133303 | CNTNAP1 | 8506 | RNAseq | 0.5346 | 0.1713 | |
| SRP159526 | CNTNAP1 | 8506 | RNAseq | 0.6671 | 0.1434 | |
| SRP193095 | CNTNAP1 | 8506 | RNAseq | 1.1117 | 0.0000 | |
| SRP219564 | CNTNAP1 | 8506 | RNAseq | 0.5815 | 0.5457 | |
| TCGA | CNTNAP1 | 8506 | RNAseq | -0.3452 | 0.0156 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CNTNAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNTNAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNTNAP1 | 8506 | 6 | 2 | 22 | |
| GSE20123 | CNTNAP1 | 8506 | 6 | 2 | 22 | |
| GSE43470 | CNTNAP1 | 8506 | 1 | 2 | 40 | |
| GSE46452 | CNTNAP1 | 8506 | 34 | 0 | 25 | |
| GSE47630 | CNTNAP1 | 8506 | 8 | 1 | 31 | |
| GSE54993 | CNTNAP1 | 8506 | 3 | 4 | 63 | |
| GSE54994 | CNTNAP1 | 8506 | 8 | 5 | 40 | |
| GSE60625 | CNTNAP1 | 8506 | 4 | 0 | 7 | |
| GSE74703 | CNTNAP1 | 8506 | 1 | 1 | 34 | |
| GSE74704 | CNTNAP1 | 8506 | 4 | 1 | 15 | |
| TCGA | CNTNAP1 | 8506 | 23 | 6 | 67 |
Total number of gains: 98; Total number of losses: 24; Total Number of normals: 366.
Somatic mutations of CNTNAP1:
Generating mutation plots.
Highly correlated genes for CNTNAP1:
Showing top 20/672 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNTNAP1 | OR2T12 | 0.831411 | 3 | 0 | 3 |
| CNTNAP1 | TCL1B | 0.790635 | 3 | 0 | 3 |
| CNTNAP1 | SFTPA2 | 0.769117 | 3 | 0 | 3 |
| CNTNAP1 | ZNF469 | 0.764659 | 3 | 0 | 3 |
| CNTNAP1 | SLC26A5 | 0.759783 | 3 | 0 | 3 |
| CNTNAP1 | OR2T33 | 0.752565 | 3 | 0 | 3 |
| CNTNAP1 | CYP4V2 | 0.741676 | 3 | 0 | 3 |
| CNTNAP1 | KIR3DL2 | 0.736234 | 3 | 0 | 3 |
| CNTNAP1 | RCAN1 | 0.730877 | 3 | 0 | 3 |
| CNTNAP1 | FOXC2 | 0.72972 | 3 | 0 | 3 |
| CNTNAP1 | CCDC149 | 0.72971 | 3 | 0 | 3 |
| CNTNAP1 | TCL6 | 0.726832 | 3 | 0 | 3 |
| CNTNAP1 | FAM167B | 0.722776 | 3 | 0 | 3 |
| CNTNAP1 | ZC3H7B | 0.719956 | 3 | 0 | 3 |
| CNTNAP1 | RCBTB1 | 0.717216 | 3 | 0 | 3 |
| CNTNAP1 | KRTAP19-2 | 0.715214 | 3 | 0 | 3 |
| CNTNAP1 | TRIM22 | 0.714058 | 3 | 0 | 3 |
| CNTNAP1 | PPP1R18 | 0.712707 | 3 | 0 | 3 |
| CNTNAP1 | MAP3K19 | 0.710764 | 3 | 0 | 3 |
| CNTNAP1 | KRTAP12-2 | 0.708013 | 3 | 0 | 3 |
For details and further investigation, click here
