| Full name: keratin associated protein 6-2 | Alias Symbol: KAP6.2 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 337967 | HGNC ID: HGNC:18932 | Ensembl Gene: ENSG00000186930 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP6-2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | KRTAP6-2 | 337967 | 20549 | 0.1406 | 0.2356 | |
| GSE53624 | KRTAP6-2 | 337967 | 20549 | 0.2794 | 0.0058 | |
| GSE97050 | KRTAP6-2 | 337967 | A_33_P3263664 | -0.4757 | 0.2237 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP6-2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP6-2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP6-2 | 337967 | 2 | 9 | 19 | |
| GSE20123 | KRTAP6-2 | 337967 | 2 | 9 | 19 | |
| GSE43470 | KRTAP6-2 | 337967 | 2 | 9 | 32 | |
| GSE46452 | KRTAP6-2 | 337967 | 1 | 21 | 37 | |
| GSE47630 | KRTAP6-2 | 337967 | 6 | 17 | 17 | |
| GSE54993 | KRTAP6-2 | 337967 | 9 | 1 | 60 | |
| GSE54994 | KRTAP6-2 | 337967 | 1 | 9 | 43 | |
| GSE60625 | KRTAP6-2 | 337967 | 0 | 0 | 11 | |
| GSE74703 | KRTAP6-2 | 337967 | 2 | 6 | 28 | |
| GSE74704 | KRTAP6-2 | 337967 | 2 | 6 | 12 |
Total number of gains: 27; Total number of losses: 87; Total Number of normals: 278.
Somatic mutations of KRTAP6-2:
Generating mutation plots.
Highly correlated genes for KRTAP6-2:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP6-2 | DEFB110 | 0.808128 | 3 | 0 | 3 |
| KRTAP6-2 | CCIN | 0.732251 | 3 | 0 | 3 |
| KRTAP6-2 | OR1L6 | 0.723751 | 3 | 0 | 3 |
| KRTAP6-2 | OR2T33 | 0.722004 | 3 | 0 | 3 |
| KRTAP6-2 | CDH24 | 0.680837 | 3 | 0 | 3 |
| KRTAP6-2 | FEV | 0.676413 | 3 | 0 | 3 |
| KRTAP6-2 | GRIA4 | 0.672469 | 3 | 0 | 3 |
| KRTAP6-2 | BARHL1 | 0.666407 | 3 | 0 | 3 |
| KRTAP6-2 | KRTAP10-9 | 0.660107 | 3 | 0 | 3 |
| KRTAP6-2 | SLC4A8 | 0.659318 | 3 | 0 | 3 |
| KRTAP6-2 | CTPS2 | 0.650636 | 3 | 0 | 3 |
| KRTAP6-2 | ZNF445 | 0.650354 | 3 | 0 | 3 |
| KRTAP6-2 | NRL | 0.644738 | 3 | 0 | 3 |
| KRTAP6-2 | SPEG | 0.634331 | 4 | 0 | 3 |
| KRTAP6-2 | PRR23C | 0.634221 | 3 | 0 | 3 |
| KRTAP6-2 | USP17L2 | 0.624934 | 3 | 0 | 3 |
| KRTAP6-2 | CELA3A | 0.624685 | 3 | 0 | 3 |
| KRTAP6-2 | RBM17 | 0.613131 | 3 | 0 | 3 |
| KRTAP6-2 | ZC3H18 | 0.61072 | 3 | 0 | 3 |
| KRTAP6-2 | GDPD4 | 0.606705 | 3 | 0 | 3 |
For details and further investigation, click here
