| Full name: zinc finger CCCH-type containing 18 | Alias Symbol: NHN1 | ||
| Type: protein-coding gene | Cytoband: 16q24.2 | ||
| Entrez ID: 124245 | HGNC ID: HGNC:25091 | Ensembl Gene: ENSG00000158545 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZC3H18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZC3H18 | 124245 | 226108_at | 0.5351 | 0.1185 | |
| GSE26886 | ZC3H18 | 124245 | 226108_at | 0.1178 | 0.5819 | |
| GSE45670 | ZC3H18 | 124245 | 226108_at | 0.5825 | 0.0000 | |
| GSE53622 | ZC3H18 | 124245 | 52251 | 0.2666 | 0.0001 | |
| GSE53624 | ZC3H18 | 124245 | 52251 | -0.2291 | 0.0203 | |
| GSE63941 | ZC3H18 | 124245 | 226108_at | 1.2947 | 0.0030 | |
| GSE77861 | ZC3H18 | 124245 | 226108_at | 0.5269 | 0.0044 | |
| GSE97050 | ZC3H18 | 124245 | A_33_P3347465 | -0.1477 | 0.4256 | |
| SRP007169 | ZC3H18 | 124245 | RNAseq | 1.7854 | 0.0061 | |
| SRP064894 | ZC3H18 | 124245 | RNAseq | 0.3105 | 0.0675 | |
| SRP133303 | ZC3H18 | 124245 | RNAseq | 0.7727 | 0.0022 | |
| SRP159526 | ZC3H18 | 124245 | RNAseq | 0.8585 | 0.0098 | |
| SRP193095 | ZC3H18 | 124245 | RNAseq | 0.6278 | 0.0000 | |
| SRP219564 | ZC3H18 | 124245 | RNAseq | 0.1492 | 0.5387 | |
| TCGA | ZC3H18 | 124245 | RNAseq | 0.1204 | 0.0143 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZC3H18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZC3H18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZC3H18 | 124245 | 4 | 3 | 23 | |
| GSE20123 | ZC3H18 | 124245 | 4 | 3 | 23 | |
| GSE43470 | ZC3H18 | 124245 | 1 | 13 | 29 | |
| GSE46452 | ZC3H18 | 124245 | 38 | 1 | 20 | |
| GSE47630 | ZC3H18 | 124245 | 11 | 9 | 20 | |
| GSE54993 | ZC3H18 | 124245 | 3 | 4 | 63 | |
| GSE54994 | ZC3H18 | 124245 | 9 | 11 | 33 | |
| GSE60625 | ZC3H18 | 124245 | 4 | 0 | 7 | |
| GSE74703 | ZC3H18 | 124245 | 1 | 9 | 26 | |
| GSE74704 | ZC3H18 | 124245 | 3 | 2 | 15 | |
| TCGA | ZC3H18 | 124245 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of ZC3H18:
Generating mutation plots.
Highly correlated genes for ZC3H18:
Showing top 20/731 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZC3H18 | SPEG | 0.842111 | 3 | 0 | 3 |
| ZC3H18 | ZCCHC3 | 0.811898 | 3 | 0 | 3 |
| ZC3H18 | CTPS2 | 0.811616 | 3 | 0 | 3 |
| ZC3H18 | OR2T33 | 0.805352 | 3 | 0 | 3 |
| ZC3H18 | KRTAP12-2 | 0.802761 | 3 | 0 | 3 |
| ZC3H18 | KRTAP10-9 | 0.800515 | 3 | 0 | 3 |
| ZC3H18 | CABIN1 | 0.788513 | 3 | 0 | 3 |
| ZC3H18 | IWS1 | 0.781862 | 3 | 0 | 3 |
| ZC3H18 | ATN1 | 0.781827 | 3 | 0 | 3 |
| ZC3H18 | SZT2 | 0.781474 | 3 | 0 | 3 |
| ZC3H18 | MEF2A | 0.774877 | 3 | 0 | 3 |
| ZC3H18 | CUX1 | 0.772033 | 4 | 0 | 4 |
| ZC3H18 | KIR3DL2 | 0.771175 | 3 | 0 | 3 |
| ZC3H18 | RFPL3S | 0.768022 | 3 | 0 | 3 |
| ZC3H18 | COA6 | 0.764268 | 3 | 0 | 3 |
| ZC3H18 | SLC26A5 | 0.759282 | 3 | 0 | 3 |
| ZC3H18 | HNRNPU | 0.754341 | 4 | 0 | 4 |
| ZC3H18 | SPATS2 | 0.753561 | 3 | 0 | 3 |
| ZC3H18 | ALG11 | 0.750056 | 3 | 0 | 3 |
| ZC3H18 | PXN | 0.747834 | 3 | 0 | 3 |
For details and further investigation, click here
