| Full name: RNA binding motif protein 17 | Alias Symbol: SPF45|MGC14439 | ||
| Type: protein-coding gene | Cytoband: 10p15.1 | ||
| Entrez ID: 84991 | HGNC ID: HGNC:16944 | Ensembl Gene: ENSG00000134453 | OMIM ID: 606935 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBM17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM17 | 84991 | 224781_s_at | 0.2178 | 0.4707 | |
| GSE20347 | RBM17 | 84991 | 221309_at | -0.0410 | 0.5730 | |
| GSE23400 | RBM17 | 84991 | 221309_at | 0.0022 | 0.9414 | |
| GSE26886 | RBM17 | 84991 | 224781_s_at | 0.1356 | 0.4565 | |
| GSE29001 | RBM17 | 84991 | 221309_at | -0.0364 | 0.8232 | |
| GSE38129 | RBM17 | 84991 | 221309_at | -0.1148 | 0.0582 | |
| GSE45670 | RBM17 | 84991 | 224781_s_at | 0.1831 | 0.0572 | |
| GSE53622 | RBM17 | 84991 | 115838 | 0.2743 | 0.0532 | |
| GSE53624 | RBM17 | 84991 | 115838 | 0.3256 | 0.0167 | |
| GSE63941 | RBM17 | 84991 | 224781_s_at | -0.0242 | 0.9510 | |
| GSE77861 | RBM17 | 84991 | 224781_s_at | 0.2305 | 0.2447 | |
| GSE97050 | RBM17 | 84991 | A_23_P35645 | -0.4199 | 0.1760 | |
| SRP007169 | RBM17 | 84991 | RNAseq | 0.9580 | 0.0176 | |
| SRP008496 | RBM17 | 84991 | RNAseq | 0.7094 | 0.0039 | |
| SRP064894 | RBM17 | 84991 | RNAseq | 0.2187 | 0.0542 | |
| SRP133303 | RBM17 | 84991 | RNAseq | 0.0545 | 0.6418 | |
| SRP159526 | RBM17 | 84991 | RNAseq | 0.1890 | 0.4577 | |
| SRP193095 | RBM17 | 84991 | RNAseq | 0.1420 | 0.1319 | |
| SRP219564 | RBM17 | 84991 | RNAseq | -0.0292 | 0.8862 | |
| TCGA | RBM17 | 84991 | RNAseq | 0.0916 | 0.0621 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RBM17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM17 | 84991 | 4 | 8 | 18 | |
| GSE20123 | RBM17 | 84991 | 4 | 7 | 19 | |
| GSE43470 | RBM17 | 84991 | 3 | 6 | 34 | |
| GSE46452 | RBM17 | 84991 | 2 | 14 | 43 | |
| GSE47630 | RBM17 | 84991 | 5 | 15 | 20 | |
| GSE54993 | RBM17 | 84991 | 11 | 0 | 59 | |
| GSE54994 | RBM17 | 84991 | 4 | 10 | 39 | |
| GSE60625 | RBM17 | 84991 | 0 | 0 | 11 | |
| GSE74703 | RBM17 | 84991 | 2 | 4 | 30 | |
| GSE74704 | RBM17 | 84991 | 1 | 7 | 12 | |
| TCGA | RBM17 | 84991 | 20 | 24 | 52 |
Total number of gains: 56; Total number of losses: 95; Total Number of normals: 337.
Somatic mutations of RBM17:
Generating mutation plots.
Highly correlated genes for RBM17:
Showing top 20/315 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM17 | KRTAP12-2 | 0.84403 | 3 | 0 | 3 |
| RBM17 | SPEG | 0.842653 | 3 | 0 | 3 |
| RBM17 | BCL9L | 0.831367 | 3 | 0 | 3 |
| RBM17 | OR1L6 | 0.805743 | 3 | 0 | 3 |
| RBM17 | MRPL32 | 0.795019 | 3 | 0 | 3 |
| RBM17 | WDR5 | 0.789247 | 3 | 0 | 3 |
| RBM17 | ALG11 | 0.7853 | 3 | 0 | 3 |
| RBM17 | SIRPB1 | 0.782192 | 3 | 0 | 3 |
| RBM17 | LTV1 | 0.773657 | 3 | 0 | 3 |
| RBM17 | SLC26A5 | 0.769579 | 3 | 0 | 3 |
| RBM17 | KRTAP10-9 | 0.768967 | 3 | 0 | 3 |
| RBM17 | SOCS4 | 0.75877 | 3 | 0 | 3 |
| RBM17 | KDM6B | 0.758495 | 3 | 0 | 3 |
| RBM17 | TMEM181 | 0.751418 | 3 | 0 | 3 |
| RBM17 | SLC4A8 | 0.750183 | 4 | 0 | 4 |
| RBM17 | ARL5B | 0.744052 | 3 | 0 | 3 |
| RBM17 | TMEM237 | 0.743413 | 3 | 0 | 3 |
| RBM17 | NQO2 | 0.741903 | 4 | 0 | 4 |
| RBM17 | MRPS5 | 0.7394 | 4 | 0 | 3 |
| RBM17 | SLC36A4 | 0.735219 | 4 | 0 | 4 |
For details and further investigation, click here
