| Full name: glycerophosphodiester phosphodiesterase domain containing 4 | Alias Symbol: GDE6 | ||
| Type: protein-coding gene | Cytoband: 11q13.5 | ||
| Entrez ID: 220032 | HGNC ID: HGNC:24849 | Ensembl Gene: ENSG00000178795 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GDPD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | GDPD4 | 220032 | 5794 | -0.0216 | 0.8460 | |
| GSE53624 | GDPD4 | 220032 | 5794 | 0.1448 | 0.1472 | |
| TCGA | GDPD4 | 220032 | RNAseq | 0.1241 | 0.8833 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GDPD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GDPD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDPD4 | 220032 | 5 | 9 | 16 | |
| GSE20123 | GDPD4 | 220032 | 5 | 8 | 17 | |
| GSE43470 | GDPD4 | 220032 | 3 | 3 | 37 | |
| GSE46452 | GDPD4 | 220032 | 8 | 21 | 30 | |
| GSE47630 | GDPD4 | 220032 | 5 | 16 | 19 | |
| GSE54993 | GDPD4 | 220032 | 8 | 2 | 60 | |
| GSE54994 | GDPD4 | 220032 | 6 | 17 | 30 | |
| GSE60625 | GDPD4 | 220032 | 4 | 3 | 4 | |
| GSE74703 | GDPD4 | 220032 | 2 | 2 | 32 | |
| GSE74704 | GDPD4 | 220032 | 3 | 4 | 13 | |
| TCGA | GDPD4 | 220032 | 20 | 31 | 45 |
Total number of gains: 69; Total number of losses: 116; Total Number of normals: 303.
Somatic mutations of GDPD4:
Generating mutation plots.
Highly correlated genes for GDPD4:
Showing all 17 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDPD4 | DEFB128 | 0.677625 | 3 | 0 | 3 |
| GDPD4 | SPEG | 0.638305 | 3 | 0 | 3 |
| GDPD4 | SEZ6 | 0.617993 | 3 | 0 | 3 |
| GDPD4 | KCTD19 | 0.615585 | 3 | 0 | 3 |
| GDPD4 | LGALS12 | 0.609191 | 3 | 0 | 3 |
| GDPD4 | OR5F1 | 0.608787 | 3 | 0 | 3 |
| GDPD4 | KRTAP6-2 | 0.606705 | 3 | 0 | 3 |
| GDPD4 | SIM1 | 0.597607 | 3 | 0 | 3 |
| GDPD4 | DEFB123 | 0.593386 | 3 | 0 | 3 |
| GDPD4 | WDR87 | 0.586192 | 3 | 0 | 3 |
| GDPD4 | TTLL2 | 0.585055 | 3 | 0 | 3 |
| GDPD4 | CPLX2 | 0.568652 | 3 | 0 | 3 |
| GDPD4 | AQP8 | 0.561965 | 3 | 0 | 3 |
| GDPD4 | CLDN19 | 0.551074 | 3 | 0 | 3 |
| GDPD4 | KCNJ13 | 0.549637 | 3 | 0 | 3 |
| GDPD4 | SLC17A4 | 0.545284 | 3 | 0 | 3 |
| GDPD4 | IFNA21 | 0.52885 | 3 | 0 | 3 |
For details and further investigation, click here
