| Full name: lipocalin 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 158062 | HGNC ID: HGNC:17337 | Ensembl Gene: ENSG00000267206 | OMIM ID: 609379 |
| Drug and gene relationship at DGIdb | |||
Expression of LCN6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LCN6 | 158062 | 1559864_at | -0.3337 | 0.0610 | |
| GSE26886 | LCN6 | 158062 | 1559864_at | -0.0175 | 0.8935 | |
| GSE45670 | LCN6 | 158062 | 1559864_at | -0.0524 | 0.5227 | |
| GSE63941 | LCN6 | 158062 | 1559864_at | 0.3996 | 0.0231 | |
| GSE77861 | LCN6 | 158062 | 1559864_at | -0.1965 | 0.0193 | |
| SRP133303 | LCN6 | 158062 | RNAseq | -2.5527 | 0.0000 | |
| SRP159526 | LCN6 | 158062 | RNAseq | -2.8036 | 0.0000 | |
| SRP219564 | LCN6 | 158062 | RNAseq | -0.8728 | 0.3446 | |
| TCGA | LCN6 | 158062 | RNAseq | -4.7851 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by LCN6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LCN6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCN6 | 158062 | 5 | 7 | 18 | |
| GSE20123 | LCN6 | 158062 | 5 | 7 | 18 | |
| GSE43470 | LCN6 | 158062 | 3 | 7 | 33 | |
| GSE46452 | LCN6 | 158062 | 6 | 13 | 40 | |
| GSE47630 | LCN6 | 158062 | 6 | 15 | 19 | |
| GSE54993 | LCN6 | 158062 | 3 | 3 | 64 | |
| GSE54994 | LCN6 | 158062 | 12 | 8 | 33 | |
| GSE60625 | LCN6 | 158062 | 0 | 0 | 11 | |
| GSE74703 | LCN6 | 158062 | 3 | 5 | 28 | |
| GSE74704 | LCN6 | 158062 | 3 | 5 | 12 | |
| TCGA | LCN6 | 158062 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of LCN6:
Generating mutation plots.
Highly correlated genes for LCN6:
Showing top 20/145 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCN6 | RPL29 | 0.804337 | 3 | 0 | 3 |
| LCN6 | TPD52L1 | 0.728956 | 3 | 0 | 3 |
| LCN6 | TSGA13 | 0.727577 | 3 | 0 | 3 |
| LCN6 | AK9 | 0.726416 | 3 | 0 | 3 |
| LCN6 | PADI1 | 0.724078 | 3 | 0 | 3 |
| LCN6 | FAM95B1 | 0.702355 | 3 | 0 | 3 |
| LCN6 | MPP7 | 0.701376 | 3 | 0 | 3 |
| LCN6 | HCG22 | 0.699906 | 3 | 0 | 3 |
| LCN6 | USP54 | 0.698501 | 3 | 0 | 3 |
| LCN6 | FAAH2 | 0.695812 | 3 | 0 | 3 |
| LCN6 | PTK6 | 0.688855 | 3 | 0 | 3 |
| LCN6 | ZNF503-AS1 | 0.683672 | 3 | 0 | 3 |
| LCN6 | CYP4F12 | 0.683458 | 4 | 0 | 3 |
| LCN6 | NEBL | 0.679336 | 3 | 0 | 3 |
| LCN6 | LINC01136 | 0.672492 | 4 | 0 | 4 |
| LCN6 | CD200R1 | 0.671426 | 3 | 0 | 3 |
| LCN6 | MIR4755 | 0.666526 | 4 | 0 | 4 |
| LCN6 | TMEM125 | 0.666442 | 3 | 0 | 3 |
| LCN6 | PNPLA2 | 0.661774 | 3 | 0 | 3 |
| LCN6 | AMHR2 | 0.66118 | 3 | 0 | 3 |
For details and further investigation, click here
